Abstract: A valve assembly for a medical device including a container including a first region and a second region, a first fluid inlet fluidly coupled to the first region, a second fluid inlet fluidly coupled to the second region, and a piston assembly disposed within the container. The container is configured to house an agent within the second region, the first fluid inlet is configured to deliver a first portion of pressurized fluid to the first region at a first pressure level, and the second fluid inlet is configured to deliver a second portion of pressurized fluid to the second region at a second pressure level that is less than the first pressure level. The piston assembly includes a valve configured to move from a first position to a second position in response to the piston assembly moving relative to the container.

Abstract: The present disclosure pertains to a syringe comprising: a syringe barrel having an open proximal end that opens into an interior having a cylindrical wall and an angled distal surface terminating at an outlet; a plunger rod; and a plunger seal, a proximal end of the plunger seal configured to be attached to a distal end of the plunger rod, and a distal end of the plunger seal configured to be inserted into the interior of the syringe barrel through the open proximal end, the plunger seal forming a seal with the cylindrical wall of the interior of the syringe barrel, and the distal end of the plunger seal terminating at an angled distal surface, wherein the angled distal surface of the syringe barrel is more acute than the angled distal surface of the plunger seal. The present disclosure also pertains to kits containing such a syringe.

Abstract: An elevator of a medical device may comprise: a plurality of segments joined together by at least one hinge, and a control element coupled to at least one segment of the plurality of segments. A first segment of the plurality of segments may be a discrete structure. Proximal or distal movement of the control element may be configured to move the at least one segment of the plurality of segments relative to another of the plurality of segments.

Abstract: A medical device system may include a control unit comprising one or more processors that implement an algorithm to enhance images obtained by a medical device. The one or more processing boards perform the steps of: receiving a first image from the first viewing element; determining a current illumination value of the first image; determining a first difference between the current illumination value and a target high illumination value if the current illumination value is greater than the target high illumination value; determining a second difference between the current illumination value and a target low illumination value if the current illumination value is less than the target low illumination value; generating a new illumination value, using at least one of the first difference and the second difference; and converting the new illumination value to a first voltage value for application to one or more illuminators of the medical device.

Abstract: An example medical device includes a container and tube set arranged and configured to couple to an endoscope, a first gas supply, and a second gas supply for use in an endoscopic procedure. The container and tube set includes a container having an interior volume configured to contain a fluid, a gas supply tube having a first end and a second end in fluid communication with the interior volume of the container, and a coupling mechanism having a first end and a second end, wherein the first end of the coupling mechanism is configured to engage with the second end of the gas supply tube and the second end of the coupling mechanism is configured to engage with both the first gas supply and the second gas supply interchangeably.

Abstract: A method for evaluating a gastrointestinal tract may include receiving an electrical signal that includes data pertaining to motility in the gastrointestinal tract of a patient and analyzing one or more characteristics of the electrical signal relative to one or more respective thresholds indicative of an occurrence or an imminence of a condition of the gastrointestinal tract.

Abstract: The present disclosure relates generally to the field of medical devices for accessing body lumens. In particular, the present disclosure relates to medical devices, systems and methods for enlarging an opening of a body lumen. In an embodiment, a device may include a flexible elongate tube. A distal end of the tube may be configured to access an opening of a body lumen. A plurality of wire lumens may extend from the distal end of the tube toward a proximal end of the tube that are radially offset from and substantially parallel with a longitudinal axis. At least a portion of the plurality of wire lumens may be exposed to an outer surface of the tube along a distal portion. A plurality of wires may each extend along a respective wire lumen. A portion of each wire may extend externally to the wire lumens exposed to the outer surface.

Abstract: The present disclosure relates to injectable compositions sterile injectable fluid compositions comprising a polysaccharide having a color in the visible spectrum, methods of forming the same, kits containing the same, and methods for performing agent-assisted procedures in a patient using the same.

Abstract: Embodiments of the invention include a medical device for accessing a patient's body portion and used for diagnosis and treatment of medical conditions. Embodiments of the invention may include a particular endoscopic positioning mechanism for placing an endoscope and an additional treatment device within desired body portions in order to assist in diagnosis and treatment of anatomical diseases and disorders. In particular, a medical device according to an embodiment of the invention may include an outer flexible tube and a positioning mechanism configured for rotating one portion of the flexible tube relative to another portion of the flexible tube.

Abstract: Aspects of stone identification methods and systems are described. According to one aspect, an exemplary method comprises: transmitting to a processing unit, with an imaging element mounted on a distal end of a scope, image data about a stone object inside a body cavity; generating from the image data, with the processing unit, a visual representation of the stone object and the body cavity; establishing from a user input, with the processing unit, a scale for the visual representation; determining from the visual representation, with the processing unit, a size of the stone object on the scale; comparing, with the processing unit, the size of the stone object with a predetermined maximum size to determine a removal status; and augmenting, with the processing unit, the visual representation to include an indicator responsive to the removal status. Associated systems are also described.

Abstract: A guidewire assembly may include a handle assembly including: a handle body; a shaft extending through the handle body; and an actuator. The guidewire assembly may further include a tube extending distally from the handle assembly and including a proximal portion and a distal portion; and an interior body extending from the handle assembly through the tube to the distal portion of the tube, wherein the interior body is coupled to the shaft. The shaft may be configured to move longitudinally through the handle body as the actuator is rotated to move interior body longitudinally through the tube.

Abstract: The present invention relates to a device for endoscopy or endosonography-guided transluminal interventions whereby two luminal structures in the body may be drawn toward each other and a fluid conduit formed in between. The device may have a hollow central member to which is coupled a distal retention member and in one embodiment a proximal retention member. The retention members may each be positioned inside one of the luminal structures and expanded from a first condition to an expanded second condition having an increased radius. The length of the central member may be shortened and its diameter expanded to approximate the two retention members and thereby the luminal structures.

Abstract: A system may include an expandable member, and a plurality of sensors disposed on an outer surface of the expandable member and circumferentially spaced apart from one another, wherein each of the plurality of sensors includes a first emitter configured to emit light of a first wavelength, and a detector configured to detect light, and a controller coupled to the plurality of sensors.

Abstract: A fluid management system includes a pump configured to pump fluid through the system at a fluid flow rate. The system includes a processor including a user interface, the user interface allowing a user to input a set of system operating parameters, the processor being configured to control the pump to maintain a target fluid flow rate based on the set of system operating parameters. The system further includes a scope device coupled to the pump to deliver fluid to a target surgical site, the scope device including an elongated shaft extending from a distal end thereof, the elongated shaft including at least one sensor, the sensor transmitting sensor data relating to target surgical site to the processor. The processor automatically signals to the pump to adjust the fluid flow rate based on the sensor data.

Abstract: Aspiration medical device as well as methods for making and using aspiration medical devices are disclosed. An example aspiration medical device may include a tubular member having a distal end region and defining an inflow orifice adjacent to the distal end region. An aspiration member may be disposed within the tubular member. The aspiration member may have a plurality of axially-spaced fluid jets formed therein.

Abstract: A delivery device may be configured to deliver an agent to a target tissue through a channel of a medical device, the delivery device may include a body including (a) a coupling region configured to removably attach to a handle of the medical device, and (b) a coupler including an exit port for aligning with a port of the channel, wherein the coupler is configured to mate with the port of the channel; a source of an agent; and a source of pressurized fluid. The body, the source of agent, and the source of pressurized fluid may be arranged to deliver agent and pressurized fluid to the exit port for delivery through the channel.

Abstract: A handle of a medical device may comprise an actuator; a lock movable relative to the actuator and having a feature movable relative to the actuator; and a rack having plurality of teeth separated from one another by a plurality of gaps. The lock may be configured to move the feature from (a) a first configuration, in which the feature is disposed in the gap, between two of the plurality of teeth, such that the two teeth inhibit the actuator from rotating; to (b) a second configuration, in which the feature is disposed outside of the gap, such that the actuator is rotatable. In the second configuration, the teeth may be disposed between the feature and the actuator.

Abstract: Systems, devices, and methods for electroporation ablation therapy are disclosed, with a protection device for isolating electronic circuitry, devices, and/or other components from a set of electrodes during a cardiac ablation procedure. A system can include a first set of electrodes disposable near cardiac tissue of a heart and a second set of electrodes disposable in contact with patient anatomy. The system can further include a signal generator configured to generate a pulse waveform, where the signal generator coupled to the first set of electrodes and configured to repeatedly deliver the pulse waveform to the first set of electrodes. The system can further include a protection device configured to selectively couple and decouple an electronic device to the second set of electrodes.

Abstract: An example introducer is disclosed. An example introducer includes an inner liner including a lumen, a distal region and at least one folded portion extending along the distal region. The introducer also includes a reinforcing member having a length and including at least one spine extending along the length of the reinforcing member. The introducer also includes a sheath disposed along at least a portion of the introducer, wherein the sheath includes at least one perforation, wherein material adjacent to the at least one folded portion is removed from a distal portion of the introducer to form a tip region. The introducer also includes a tip member disposed along the tip region.

Abstract: A catheter includes a handle and an elongate member extending from the handle. The catheter may also include steering system coupled to the handle. The steering system may be configured to deflect at least a portion of the elongate member in at least one direction. The catheter may also include a locking mechanism configured to lock the portion of the elongate member in a deflected configuration, and a lever coupled to the handle. The lever may be configured to move from a first position to a second position to engage the locking mechanism. The lever may also be configured to be separably retained at least at one of the first position or the second position to prevent movement therebetween.