Patents Assigned to SCIPHER MEDICINE CORPORATION
  • Methods of treating a subject with an alternative to anti-TNF therapy
    Patent number: 11987620
    Abstract: Methods of treating a subject suffering from an autoimmune disease, disorder, or condition with an alternative to anti-TNF therapy.
    Type: Grant
    Filed: November 2, 2021
    Date of Patent: May 21, 2024
    Assignee: SCIPHER MEDICINE CORPORATION
    Inventors: Keith J. Johnson, Susan Ghiassian
  • Methods of treating a subject suffering from rheumatoid arthritis with alternative to anti-TNF therapy based in part on a trained machine learning classifier
    Patent number: 11783913
    Abstract: Presented herein are systems and methods for developing classifiers useful for predicting response to particular treatments. For example, in some embodiments, the present disclosure provides a method of treating subjects suffering from an autoimmune disorder, the method comprising administering an alternative to anti-TNF therapy to subjects who have been determined to be non-responsive via a classifier established to distinguish between responsive and non-responsive prior subjects in a cohort who have received the anti-TNF therapy.
    Type: Grant
    Filed: August 4, 2022
    Date of Patent: October 10, 2023
    Assignee: SCIPHER MEDICINE CORPORATION
    Inventors: Susan Ghiassian, Theodore R. Mellors, Marc Santolini, Asher Ameli, Nancy Schoenbrunner, Viatcheslav R. Akmaev, Keith J. Johnson
  • Methods of treating a subject suffering from rheumatoid arthritis based in part on a trained machine learning classifier
    Patent number: 11456056
    Abstract: Presented herein are systems and methods for developing classifiers useful for predicting response to particular treatments. For example, in some embodiments, the present disclosure provides a method of treating subjects suffering from an autoimmune disorder, the method comprising a step of: administering an anti-TNF therapy to subjects who have been determined to be responsive via a classifier established to distinguish between responsive and non-responsive prior subjects in a cohort who have received the anti-TNF therapy.
    Type: Grant
    Filed: November 2, 2021
    Date of Patent: September 27, 2022
    Assignee: SCIPHER MEDICINE CORPORATION
    Inventors: Susan Ghiassian, Theodore R. Mellors, Marc Santolini, Asher Ameli, Nancy Schoenbrunner, Viatcheslav R. Akmaev, Keith J. Johnson
  • Methods and systems for predicting response to anti-TNF therapies
    Patent number: 11198727
    Abstract: Methods and systems for administering anti-TNF therapy to subjects who have been determined to display a gene expression response signature established to distinguish between responsive and non-responsive prior subjects who have received the anti-TNF therapy.
    Type: Grant
    Filed: April 25, 2019
    Date of Patent: December 14, 2021
    Assignee: SCIPHER MEDICINE CORPORATION
    Inventors: Keith J. Johnson, Susan Dina Ghiassian
  • Method of treating a subject suffering from rheumatoid arthritis with anti-TNF therapy based on a trained machine learning classifier
    Patent number: 11195595
    Abstract: Presented herein are systems and methods for developing classifiers useful for predicting response to particular treatments. For example, in some embodiments, the present disclosure provides a method of treating subjects suffering from an autoimmune disorder, the method comprising a step of: administering an anti-TNF therapy to subjects who have been determined to be responsive via a classifier established to distinguish between responsive and non-responsive prior subjects in a cohort who have received the anti-TNF therapy.
    Type: Grant
    Filed: May 10, 2021
    Date of Patent: December 7, 2021
    Assignee: SCIPHER MEDICINE CORPORATION
    Inventors: Susan Dina Ghiassian, Theodore R. Mellors, Marc Santolini, Asher Ameli, Nancy Schoenbrunner, Viatcheslav R. Akmaev, Keith J. Johnson