Abstract: A heat exchanger system includes a shell-side manifold including a plurality of shell-side ports spaced along the shell-side manifold, a tube-side manifold including a plurality of tube-side ports spaced along the tube-side manifold, a plurality of shell-and-tube heat exchangers fluidically connected in parallel between the shell-side manifold and the tube-side manifold, wherein each of the plurality of shell-and-tube heat exchangers includes a tube bundle coupled between a header and a shell and including a plurality of tubes extending through the shell and in fluid communication with a header inlet port and a header discharge port and sealed from a shell inlet port and a shell discharge port.