Patents Assigned to scPharmaceuticals Inc.
  • Concentrated liquid pharmaceutical formulations of furosemide
    Patent number: 11571434
    Abstract: Disclosed herein, in part, are liquid pharmaceutical formulations comprising furosemide or a pharmaceutically acceptable salt thereof, one or more pharmaceutically acceptable excipients, and a pharmaceutically acceptable buffer. Methods of treating congestion, edema, fluid overload, or hypertension in a patient in need thereof are also provided.
    Type: Grant
    Filed: August 2, 2022
    Date of Patent: February 7, 2023
    Assignee: scPharmaceuticals Inc.
    Inventors: Alfredo Grossi, Britt Kostraba, Olatokumbo O. Luca Ogunleye, Shannon Terry, Franciscus Koppenhagen
  • Concentrated liquid pharmaceutical formulations of furosemide
    Patent number: 11559535
    Abstract: Disclosed herein, in part, are liquid pharmaceutical formulations comprising furosemide or a pharmaceutically acceptable salt thereof, one or more pharmaceutically acceptable excipients, and a pharmaceutically acceptable buffer. Methods of treating congestion, edema, fluid overload, or hypertension in a patient in need thereof are also provided.
    Type: Grant
    Filed: August 5, 2022
    Date of Patent: January 24, 2023
    Assignee: scPharmaceuticals Inc.
    Inventors: Alfredo Grossi, Britt Kostraba, Olatokumbo O. Luca Ogunleye, Shannon Terry, Franciscus Koppenhagen
  • Concentrated liquid pharmaceutical formulations of furosemide
    Patent number: 11497755
    Abstract: Disclosed herein, in part, are liquid pharmaceutical formulations comprising furosemide or a pharmaceutically acceptable salt thereof, one or more pharmaceutically acceptable excipients, and a pharmaceutically acceptable buffer. Methods of treating congestion, edema, fluid overload, or hypertension in a patient in need thereof are also provided.
    Type: Grant
    Filed: February 18, 2022
    Date of Patent: November 15, 2022
    Assignee: scPharmaceuticals Inc.
    Inventors: Alfredo Grossi, Britt Kostraba, Olatokumbo O. Luca Ogunleye, Shannon Terry, Franciscus Koppenhagen
  • Pharmaceutical formulations for subcutaneous administration of furosemide
    Patent number: 11433044
    Abstract: The present teachings relate to liquid pharmaceutical formulations of furosemide, where the pharmaceutical formulations include a molar excess of tris(hydroxymethyl)aminomethane to furosemide, have a pH in the range of 7 to 8.5, and a concentration of tris(hydroxymethyl)aminomethane greater than or equal to about 50 mM. The present teachings can improve the stability of liquid pharmaceutical formulations including furosemide and the suitability of such pharmaceutical formulations for subcutaneous administration or delivery.
    Type: Grant
    Filed: March 7, 2019
    Date of Patent: September 6, 2022
    Assignee: scPharmaceuticals Inc.
    Inventors: Scott A. Michaels, Pieter Muntendam, Glenn R. Larsen
  • Pharmaceutical formulations for subcutaneous administration of furosemide
    Patent number: 10272064
    Abstract: The present teachings relate to liquid pharmaceutical formulations of furosemide, where the pharmaceutical formulations include a molar excess of tris(hydroxymethyl)aminomethane to furosemide, have a pH in the range of 7 to 8.5, and a concentration of tris(hydroxymethyl)aminomethane greater than or equal to about 50 mM. The present teachings can improve the stability of liquid pharmaceutical formulations including furosemide and the suitability of such pharmaceutical formulations for subcutaneous administration or delivery.
    Type: Grant
    Filed: January 23, 2018
    Date of Patent: April 30, 2019
    Assignee: scPharmaceuticals Inc.
    Inventors: Scott A. Michaels, Pieter Muntendam, Glenn R. Larsen
  • Pharmaceutical formulations for subcutaneous administration of furosemide
    Patent number: 9884039
    Abstract: The present teachings relate to liquid pharmaceutical formulations of furosemide, where the pharmaceutical formulations include a molar excess of tris(hydroxymethyl)aminomethane to furosemide, have a pH in the range of 7 to 8.5, and a concentration of tris(hydroxymethyl)aminomethane greater than or equal to about 50 mM. The present teachings can improve the stability of liquid pharmaceutical formulations including furosemide and the suitability of such pharmaceutical formulations for subcutaneous administration or delivery.
    Type: Grant
    Filed: April 3, 2014
    Date of Patent: February 6, 2018
    Assignee: scPharmaceuticals Inc.
    Inventors: Scott A. Michaels, Pieter Muntendam, Glenn R. Larsen
  • Combination Therapy for Subcutaneous Administration of Glycopeptide Antibiotics
    Publication number: 20160082075
    Abstract: A combination drug therapy is disclosed for the treatment of a patient, such as a human, with a glycopeptide antibiotic. The methods can include subcutaneous administration to a patient of a therapeutically effective amount of a glycopeptide antibiotic, for example, vancomycin, and a compound belonging to the cromones class of anti-inflammatory agents such as cromolyn sodium. The present teachings also provide a therapeutic combination and a kit including the therapeutic combination.
    Type: Application
    Filed: March 25, 2014
    Publication date: March 24, 2016
    Applicant: scPharmaceuticals Inc.
    Inventor: Pieter Muntendam
  • Pharmaceutical Formulations for Subcutaneous Administration of Furosemide
    Publication number: 20160051507
    Abstract: The present teachings relate to liquid pharmaceutical formulations of furosemide, where the pharmaceutical formulations include a molar excess of tris(hydroxymethyl)aminomethane to furosemide, have a pH in the range of 7 to 8.5, and a concentration of tris(hydroxymethyl)aminomethane greater than or equal to about 50 mM. The present teachings can improve the stability of liquid pharmaceutical formulations including furosemide and the suitability of such pharmaceutical formulations for subcutaneous administration or delivery.
    Type: Application
    Filed: April 3, 2014
    Publication date: February 25, 2016
    Applicant: scPharmaceuticals Inc.
    Inventors: Scott A. Michaels, Pieter Muntendam, Glenn R. Larsen