Abstract: A determination of supramolecular organization in a substance includes target molecules and nanocarriers at least one of which is luminescent, based on a step of collecting of lifetime decay data of at least a standard substance pure or substantially pure where a known organization state of the target molecules and the nanocarriers is pure or substantially pure; and a step of comparing the standard data and test data from a test substance.
Type:
Grant
Filed:
November 8, 2021
Date of Patent:
February 27, 2024
Assignees:
SCUOLA NORMALE SUPERIORE, UNIVERSITÀ DEGLI STUDI DI ROMA “LA SAPIENZA”, FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
Inventors:
Francesco Cardarelli, Fabio Beltram, Paolo Maria Tentori, Giulio Caracciolo, Daniela Pozzi
Abstract: A determination of supramolecular organization in a substance includes target molecules and nanocarriers at least one of which is luminescent, based on a step of collecting of lifetime decay data of at least a standard substance pure or substantially pure where a known organization state of the target molecules and the nanocarriers is pure or substantially pure; and a step of comparing the standard data and test data from a test substance.
Type:
Application
Filed:
November 8, 2021
Publication date:
October 26, 2023
Applicants:
SCUOLA NORMALE SUPERIORE, UNIVERSITÀ DEGLI STUDI DI ROMA "LA SAPIENZA", FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
Inventors:
Francesco CARDARELLI, Fabio BELTRAM, Paolo Maria TENTORI, Giulio CARACCIOLO, Daniela POZZI
Abstract: The present invention refers to a method for determining the ability of an immunoglobulin to bind to a post-translationally modified target in an intracellular environment, which folds and it is post-translationally modified as a native protein intracellularly. The present invention also refers to antibodies obtained by the above method and uses thereof.
Abstract: The present invention refers to a method for determining the ability of an immunoglobulin to bind to a post-translationally modified target in an intracellular environment, which folds and it is post-translationally modified as a native protein intracellularly. The present invention also refers to antibodies obtained by the above method and uses thereof.
Abstract: A three-dimensional nanoresonator structure has a stack of laterally confined layers including at least a first layer and a second layer of different conductive materials between which a dielectric layer is interposed. The layers have at least a respective accessible surface area exposed to an environment in which the structure is immersed. Multiple three-dimensional nanoresonators that can be dispersed in an environment are formed from an array of nanoresonators fixed to a sacrificial substrate. The nanoresonators are subsequently separated from the substrate and conjugated with a chemical agent adapted to promote the formation of a stable colloidal suspension of nanoresonators in a liquid medium.
Type:
Grant
Filed:
December 31, 2013
Date of Patent:
June 14, 2016
Assignees:
FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA, SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA, SCUOLA NORMALE SUPERIORE
Abstract: A method for analyzing data from the web that determine the importance that a chosen subject has in society, e.g., subject matter relating a concert, a scientific discovery, a football match, a person, a corporation, a brand, or a car, and analyze such data that can represent the entire society better than the known techniques. The method according to the invention can avoid malicious alterations and is able to measure and detect the temporal relations among all the web resources that talk about a particular topic or subject matter.
Abstract: A method for analyzing data from the web that determine the importance that a chosen subject has in society, e.g., subject matter relating a concert, a scientific discovery, a football match, a person, a corporation, a brand, or a car, and analyze such data that can represent the entire society better than the known techniques. The method according to the invention can avoid malicious alterations and is able to measure and detect the temporal relations among all the web resources that talk about a particular topic or subject matter.
Abstract: A semiconductor laser includes a laser resonator (1) having a planar active region (3), a first (2) and a second (6) wave-guide layer that define the active region (3). The resonator (1) has a shape that is defined by a perimeter, along which the first layer (2) radiation guide has a plurality of cuts (4) forming a lattice. The cuts are made as at least two adjacent slits (4a, 4b) and a zone between the slits in which an uncut portion (5a) of wave-guiding layer is present. In the case of a circular semiconductor laser, the number of cuts (4) is a prime number, or an odd number that is a multiple of a prime number, the prime number being greater than or equal to five. This way, it is avoided that resonance modes evolve outside of the zone with the cuts, or in any case with a component that is different from zero of the wave vector in a radial direction, and a pure whispering gallery operating mode is obtained, with maximum of the emitted radiation that evolves in a vertical direction, i.e.
Type:
Application
Filed:
November 5, 2010
Publication date:
April 7, 2011
Applicant:
SCUOLA NORMALE SUPERIORE
Inventors:
Alessandro TREDICUCCI, Fabio BELTRAM, Lucas MAHLER