Abstract: The present disclosure relates to a complementary double-stranded oligo, in which, for the amplification of a particular gene sequence, an inosine linker is linked to the 5?-terminus of a primer for the corresponding sequence, a sequence complementary to the primer is linked to the inosine linker, and at least one mis-matched nucleotide is included in the complementary sequence to form a bubble structure; in which, depending on the treatment temperature, at a predetermined temperature or lower, a single stranded oligo is turned into a double-stranded form to exist in an inactivation form, and at a predetermined temperature or higher, the oligo is activated into a single-stranded oligo; and in which, a fluorescent substance (reporter dye) and a quenching material (quencher molecule) are attached to the oligo, so that the oligo can be applied as a primer or a probe, and thus only two oligos can realize the gene amplification and fluorescent signal real-time measurement with high specificity, and to a measuring
Type:
Grant
Filed:
June 22, 2021
Date of Patent:
August 4, 2026
Assignee:
SD BIOSENSOR, INC.
Inventors:
Yoo Deok Won, Hae Joon Park, Hyo Jin Seong, Sun Young Lee
Abstract: Provided is a genome extraction device including a flow cover, more particularly a genome extraction device which includes a base plate, thereby forming a closed flow path inside and preventing a problem of narrowing of the flow path according to close contact coupling between components.
Type:
Grant
Filed:
November 18, 2021
Date of Patent:
January 13, 2026
Assignee:
SD BIOSENSOR, INC.
Inventors:
Young-Shik Cho, Sunyoung Lee, Kwanhun Lim, In-Ae Kim, Dong-Hun Kim, Hae-Joon Park, Hyo-Lim Park
Abstract: The present invention relates to a glucose diffusion control layer solution for a continuous blood glucose-measuring biosensor, a glucose diffusion control layer for a continuous blood glucose-measuring biosensor, comprising the same, and a continuous blood glucose-measuring biosensor comprising the same. More specifically, the present invention relates to: a glucose diffusion control layer solution for a continuous blood glucose-measuring biosensor, in which, by using only a substance of which biocompatibility has been verified, stability can be ensured even when injected into the human body, and glucose permeability and water absorbance can be controlled; a glucose diffusion control layer for a continuous blood glucose-measuring biosensor, comprising the same; and a continuous blood glucose-measuring biosensor comprising the same.
Type:
Application
Filed:
February 1, 2023
Publication date:
May 15, 2025
Applicant:
SD BIOSENSOR, INC.
Inventors:
Jaewook BAEK, Gyeongwan YU, Indon OH, Geunhoe KIM
Abstract: Provided is a genome extraction device to which a dual chamber structure of an outer chamber and an inner chamber is applied, more particularly a genome extraction device to which the above-described dual chamber structure is applied so that the genome extraction device can be stored stably for a long time without the risk of reagent leakage.
Type:
Grant
Filed:
November 18, 2021
Date of Patent:
March 4, 2025
Assignee:
SD BIOSENSOR, INC.
Inventors:
Young-Shik Cho, Hae-Joon Park, Sunyoung Lee, Kwanhun Lim, In-Ae Kim, Dong-Hun Kim
Abstract: Provided is an amplification module with a gas moving passage and an extract moving passage, more particularly an amplification module in which, when an extract is input from a genome extraction device in which the amplification module is installed, a quantitative amount of the extract is input to each accommodating portion so that the accuracy of detection can be increased.
Type:
Grant
Filed:
November 18, 2021
Date of Patent:
July 16, 2024
Assignee:
SD BIOSENSOR, INC.
Inventors:
Young-Shik Cho, Hae-Joon Park, Sunyoung Lee, Kwanhun Lim, Dong-Hun Kim, In-Ae Kim, Hyo-Lim Park