Abstract: The present invention relates to relates to a pharmaceutical composition comprising a combination of N-acetylcysteine with at least one inhibitor of regulated necrotic cell death, such as necroptosis and/or ferroptosis.
Type:
Application
Filed:
December 4, 2023
Publication date:
September 10, 2026
Applicants:
Seabelife, Universite de Rennes, Institut National de la Santé et de la Recherche Médicale, Ecole des Hautes Études en Santé Publique (EHESP)
Inventors:
Mélanie SIMOES EUGENIO, Marie-Thérèse DIMANCHE-BOITREL, Sophie BELAL, Morgane ROUSSELOT
Abstract: The present invention relates to a compound of the following general formula (I) or a pharmaceutically acceptable salt and/or solvate thereof, for use as drug for inhibiting ferroptosis.
Type:
Application
Filed:
January 25, 2022
Publication date:
April 11, 2024
Applicants:
Seabelife, Centre National de la Recherche Scientifique (CNRS), Sorbonne Universite, Institut National de la Santé et de la Recherche Médicale (INSERM), Université Claude Bernard Lyon 1, Universite de Rennes 1