Abstract: Methods and compositions for preparation of frozen fermented food products using antifreeze polypeptide-expressing microorganisms are provided. In particular the invention provides for use of fish antifreeze polypeptide-expressing microorganisms in fermentation of milk to produce and store frozen yogurt.

Abstract: Novel medicinally-useful compounds are provided herein. These compounds include isomeric cyclic tetramers of formaldehyde and 1-naphthol, and the derivatives or analogues of such cyclic tetramers, and linear oligomers of chromotropic acid, or its derivatives or analogues with naphthalene.

Abstract: A method, and mediating agents are provided for mediating the physiological effects of hormones, neurotransmitters, calcium-channel antagonists, chemotactic peptides or chemotactic proteins. The mediating agents provided herein are bioactive conformations of peptide hormones, neurotransmitters, calcium-channel antagonist drugs or chemotatic peptides, or analogues, agonists or antagonists thereof, or synthetic analogue substances, having Ca.sup.2+ and/or Mg.sup.2+ ions optimally and optimally-conformationally bound to the respective compound. The Ca.sup.2+ antagonist/agonist may bind Mg.sup.2+ and thus may also block calcium-channel. In the one method, the concentration of intracellular Ca.sup.2+ is raised by means of such mediating agents. A second method is also provided for delivering Ca.sup.2+ and/or Mg.sup.2+ to a membrane-bound receptor by transporting Ca.sup.2+ and/or Mg.sup.2+ through a cell membrane using the above-described mediating agents.