Abstract: The present invention relates to a nucleic acid complex having a novel structure, which can introduce a bioactive nucleic acid into cells, a composition for treating and diagnosing disease, which comprises the same, and a method of regulating expression of a target gene using the same, and more particularly to a nucleic acid complex comprising a bioactive nucleic acid complementarily bound to a carrier peptide nucleic acid modified to be generally positively charged, a composition for treating and diagnosing disease, which comprises the same, and a method of regulating expression of a target gene using the same.
Type:
Grant
Filed:
August 9, 2017
Date of Patent:
August 18, 2020
Assignee:
SEASUN THERAPEUTICS
Inventors:
Goonho Jeo, Hye Joo Kim, Ji-Yeon Yu, Chinbayar Batochir, Deokhwe Hur, Hee Kyung Park