Abstract: Cyclic peptide antibiotics including the loloatins are effective in the treatment of rosacea, particularly when administered in conjunction with an antibiotic such as metronidazole that is effective against anaerobic bacteria.
Abstract: Several cyclic decapeptides having antibiotic activity are disclosed. The decapeptides are active against both gram positive and gram negative bacteria.
Type:
Grant
Filed:
September 29, 1998
Date of Patent:
September 14, 2004
Assignees:
SeaTek Marine Biotechnology, Inc., University of British Columbia
Inventors:
Michael T. Kelly, Raymond J. Andersen, Jeff Gerard