Abstract: Pharmaceutical composition comprises of Chlorophyllin or salts thereof and its utilities including method of treatment, enabling the absorption of Copper-isochlorin e4 into human blood that results in an increase in lymphocyte count and decrease in the abundance of hematopoietic stem and progenitor cells (HPSCs) in human blood. The invention is directed to the treatment of conditions including corona-virus infection, immunosuppression, leucopenia and lymphopenia. The composition disclosed in the invention is thus useful for the treatment of corona virus disease caused by SARS-CoV-2 infection by decreasing viral infection, reducing cytokine storm and pro-inflammatory chemokines, reducing epithelial-cell oxidative-stress in the lungs and increasing the production of leukocytes.

Abstract: The present invention describes the method of using a synthetic organoselenium compound, DSePA for management of non-small cell lung carcinoma (NSCLC) and chronic myelogenous leukemia (CML). The method comprises administering DSePA orally at a dosage of 1 mg/Kg body weight daily for inhibiting the growth of A549 (representative of NSCLC) and K562 (representative of CML) tumor in mice models. Additionally, the said compound also inhibits the proliferation of other cancer cells of NSCLC (HOP-62 and H460), breast (MDA-MB-231), white blood cells (JURKAT and U-937), oral (SCC-40), colon (HT-29), kidney (A498) and cervix (SiHA) origins in cellular models at a much lower concentration than that needed to inhibit the growth of normal cells.

Abstract: The present invention discloses single crystal based phoswich detector for discriminating various kinds of radiations. The invented phoswich detector comprises a single crystal based scintillator having at least a pair of single crystals with identical refractive indices and different scintillation kinetics and a photo-sensor coupled to the single crystal based scintillator to detect a scintillation light pulse generated through interaction of radiation elements with the pair of the single crystals for discrimination of different kinds of radiation elements based on a dissimilarity in the scintillation light pulse shapes generated through the interactions.

Abstract: A method of treatment of disease condition resulting from deficiency of hematopoietic stem and progenitor cells and/or epidermal stem cells in skin comprising: administering to the subject suffering from said disease conditions, an effective amount of Jack bean lectin or a pharmaceutically acceptable salt thereof for increasing the abundance of hematopoietic stem cells and progenitor cells in bone marrow and/or epidermal stem cells in skin in vivo. Method of treating said conditions in a subject involves administering a single injection of lectin in a dose range of 0.5-2.0 mg/kg body weight to mouse leading to 2.815 to 3.55 fold increase in the abundance of epidermal stem cells in skin and a dose range of 8.0-10.0 mg/Kg body weight to a mouse leading to 2.36 to 6.67-fold increase in the abundance of hematopoietic stem and progenitor cells in bone marrow.

Abstract: The present invention discloses single crystal based phoswich detector for discriminating various kinds of radiations. The invented phoswich detector comprises a single crystal based scintillator having at least a pair of single crystals with identical refractive indices and different scintillation kinetics and a photo-sensor coupled to the single crystal based scintillator to detect a scintillation light pulse generated through interaction of radiation elements with the pair of the single crystals for discrimination of different kinds of radiation elements based on a dissimilarity in the scintillation light pulse shapes generated through the interactions.

Abstract: An arrangement of coaxial windings is provided. The arrangement includes primary and secondary windings as air-core pulse transformers having insulation and winding arrangement for efficient energy transfer to the secondary winding. The secondary winding is wound with a central metallic core to include a coaxial transmission line with it and is configured to deliver a rectangular pulse across its terminals. The arrangement also includes a coaxial feeding arrangement for the primary winding with a central coaxial terminal connecting to one end of an adjustable primary closing switch electrode so as to have variable voltage feed input corresponding to its load requirement.

Abstract: In one implementation, a passive core decay heat transport system comprising of a device in the reactor core and an assembly of heat dissipating fins is disclosed. The device comprises at least one coolant channel 2 containing the fuel assembly 3; at least one collect joint 4 connecting the fuel in the assembly to shield plug 6; at least one liquid metal thermo-siphon 5 for transporting of decay heat from fuel; at least one other liquid metal thermo-siphon 7 for transport of heat from thermo-siphon 5; and at least an assembly of heat dissipating fins 10 for transport of heat from thermo-siphon 7 to ultimate sink. The thermal expansion of the liquid metal by melting establishes the conductive and convective heat transfer paths and transfers the heat from the fuel assembly 3 to the thermo-siphon 5, which transports the heat to other thermo-siphon 7 and then to the assembly of fin 10, which dissipates the heat by natural circulation of air to atmospheric air.

Abstract: Provided herein is a process for removal of 99Tc from liquid intermediate level waste (ILW) of spent fuel reprocessing including the steps of: adding HNO3 to ILW till the pH is 2 to destroy the carbonates, transferring the ILW derived of carbonates to a tank containing mild steel wool (msw) for 4 to 48 hrs, subjecting the ILW and MS Wool to the step of separation, discharging the supernatant solution free of 99Tc and retaining the corrosion products (goethite(FeOOH/magnetite), subjecting the said corrosion products to the step of vitrification, and storing the said vitrified 99Tc bearing waste.

Abstract: The present invention relates to method and device invention made in SS316LN for tuning single-cell or multi-cell SCRF cavity for precise slow and fast tuning with low hysteresis. The tuning mechanism (device) for SCRF cavity consists of two thick square flanges connected to each other through two parallel sets of X-link levers pivoted in between such that the motion of top end of flange and bottom end of flange equalizes; wherein the top end of X-link connects one square flange to the bottom end of the other square flange and vice-versa using thin flat flexure plates; wherein the flexure plates are joined on X-link and square flange by bolts having spring locks; the square flanges have platform on the top that transfer motion and these are connected through power screw mechanism; wherein the power screw for linear actuation is rotated using worm-wheel.

Abstract: A method of increasing abundance of hematopoietic stem cells and progenitor cells and an adjuvant method of radiotherapy based treatment for radioprotection of the subject against ?-radiation toxicity and/or IR-induced death of cancer cells involving pharmaceutically effective dosages of chlorophyllin or a pharmaceutically acceptable salt thereof. The advancement is directed to selectively protect normal hematopoietic stem cells and/or sensitizes radio-resistant cancer cells to gamma radiation thereby lowering the risk of normal tissue radiation toxicity. The effective dose of the CHL formulation synergistically improves the outcome of radiotherapy for cancer when administered to the subject prior the radiotherapy for treating cancer. Also disclosed is kit having chlorophyllin containing therapeutic preparation for treating indications selected from reduction in hematopoietic stem cells and progenitor cells (HSPCs) and/or protection against whole body irradiation induced mortality.

Abstract: This invention relates to a sensor device consisting of long period gratings made of rare-earth doped double clad fiber, which is written by CO2 laser irradiation while the fiber is held static, for gamma dose measurement in the range of 150 Gy-2.5 kGy, extendable to 20 kGy, which measurements are real-time and can be from remote locations. The sensor device has high wavelength dip shift sensitivity of at least 2.8 nm/kGy, and its radiation-induced changes are near permanent. The gratings demonstrate negligible temperature sensitivity and the shifts recorded show negligible annealing at room temperature.

Abstract: The present invention provides a high voltage regulated DC power supply with full range 24 pulse input for ripple free output for high power RF amplifier, comprising: full range 24 pulse 3 phase 11 kV input system configured to provide uncontrolled low voltage DC bus, low input harmonics and high input power factor; a plurality of DC-DC power modules having their output connected in a series and coupled to the said DC bus voltage; each power module comprising a DC source, an inverter bridge IGBTs operating at predefined duty cycle and staggered to reduce the output ripple and output stored energy; and a combination of feed forward and feedback control circuit adapted to regulate the variations in the input line voltage and the variation in output at various load current to finally obtain ripple free high voltage output.

Abstract: A system for on-line detection of incipient cracks in turbine blades to serve as early warning system for turbine blade failure. The system of non-intrusive detection of turbine blade condition of the invention is simple and cost effective and would enable assessing the health of the turbine blade during plant operation, which is extremely important for the safe operation of the turbine in an operating power plant. The present method and system of identifying the presence of modulated blade passing frequency (BPF) for blade vibration that is not correlatable to the change in the operating condition and would thus be indicative of presence of cracked blades with incipient cracking. It is capable for verifying the Campbell diagram and ascertain the margin available between the natural frequency of the blade/stage and the steam excitation frequencies/engine orders.

Abstract: A method for the synthesis of OSL grade polycrystalline mass of ceramic materials with dopant C involving source ceramic material preferably in its readily available powder form comprising the steps of melting of the said ceramic material in graphite environment including a graphite crucible/container in vacuum; and obtaining there from polycrystalline aggregate by rapid solidification of said melt to thereby provide said polycrystalline mass of ceramic materials with dopant C of optically stimulated luminescence grade. The said powder form of the ceramic material is compacted and formed into pellets before subjecting to melting.

Abstract: The present disclosure relates to ceramic fillers and methods for preparing said ceramic fillers. The present disclosure further relates to dielectric resonator, fluoropolymer-ceramic filler compositions and their corresponding laminates along with their respective methods for preparing the same from the ceramic fillers. The present disclosure further provides a dielectric resonator and fluoropolymer-ceramic filler laminates having enhanced dielectric properties. The present disclosure also relates to various microwave applications of such fillers, resonators and laminates including microwave devices and circuits.

Abstract: Niobium or its alloy based Superconducting Radio Frequency (SCRF) Cavities involving atleast one laser beam welded components in the SCRF cavity welded from inside surface of the wall of cavity directed to achieving more than half the thickness to full depth penetration with minimum HAZ, minimizing distortion and shrinkage. The method ensures improved weld quality and surface finish substantially free of any weld defects. Also disclosed is the welding nozzle system and welding rigs adapted to facilitate such laser welding of the Niobium or its alloy based Superconducting Radio Frequency (SCRF) Cavities. The invention is thus directed to enhancing productivity, ensuring consistent quality and reliability, enhanced weld penetration with minimum HAZ, smooth finish of weld joints at possible reduced costs.

Abstract: An improved process for the preparation of high purity rare metal compounds such as oxides utilizing TBP (Tri-Butyl Phosphate)-nitrate solvent extraction technique adapted to manufacture nuclear grade rare metal compounds such as zirconium oxide wherein the said process substantially aids in reducing the specific generation of ammonium nitrate effluent volume thereby increasing its concentration when the said effluent comprising ammonium nitrate and ammonium sulphate are utilized for stripping of the said rare metal compound from the organic solvent in the said process of production of high purity rare metal oxide powder.

Abstract: The present disclosure relates to ceramic fillers and methods for preparing said ceramic fillers. The present disclosure further relates to dielectric resonator, fluoropolymer-ceramic filler compositions and their corresponding laminates along with their respective methods for preparing the same from the ceramic fillers. The present disclosure further provides a dielectric resonator and fluoropolymer-ceramic filler laminates having enhanced dielectric properties. The present disclosure also relates to various microwave applications of such fillers, resonators and laminates including microwave devices and circuits.

Abstract: A polymer composite with superior granulometric properties for the extraction of active and non-active cesium from high level acidic radioactive nuclear waste and/or other inorganic wastes/solutions that is particularly useful to nuclear industry. The void volumes of the said polymer composite is varied to obtain the desired Cs ion exchange kinetics wherein the composite material is radiation resistant and stable in highly acidic and alkaline medium.

Abstract: The novel lipophilic metal extractants of the class dialkyldiaza-tetraalkyloctanediamide (DADA) useful to selectively separate trivalent americium (sup. 241 Am) from trivalent lanthanides are represented by the formula 1: Wherein R is a C1 to C5 normal alkyl and R? is a C4 to C8 normal and branched alkyl group. The compounds are synthesized at high yield and purity by the reaction of corresponding N,N?-dialkylethylenediamine and N,N-dialkyl-2-chloroacetamide. The separation is achieved by utilizing the soft-soft interaction between the trivalent actinides and ‘N’ atoms of the extractant. Both soft donor “n” and hard donor ‘O’ sites are incorporated in the molecule for better extraction of trivalent actinides over trivalent lanthanides. Thus, this molecule can be used as selective extractant to separate trivalent actinides from trivalent lanthanides.