Abstract: The invention relates to an antimicrobial surface, in particular a surface functionalised with a peptide comprising an antimicrobial moiety. The invention comprises a surface functionalised with a peptide comprising an antimicrobial moiety and a binder moiety, wherein the peptide is immobilized on the surface by electrostatic interactions between the binder moiety and the surface. Further provided is a medical device, a peptide and a method for the immobilization of a peptide.
Type:
Grant
Filed:
February 25, 2015
Date of Patent:
December 10, 2019
Assignees:
The University of Birmingham, The Secretary of State for Defence of the United Kingdom of Great Britain and Northern Ireland
Inventors:
Artemis Stamboulis, Felicity Jane de Cogan, Robert Scott, Anna Frances Acushia Peacock
Abstract: The invention relates to an antimicrobial surface, in particular a surface functionalised with a peptide comprising an antimicrobial moiety. The invention comprises a surface functionalised with a peptide comprising an antimicrobial moiety and a binder moiety, wherein the peptide is immobilized on the surface by electrostatic interactions between the binder moiety and the surface. Further provided is a medical device, a peptide and a method for the immobilization of a peptide.
Type:
Application
Filed:
February 25, 2015
Publication date:
March 2, 2017
Applicants:
The University of Birmingham, The Secretary of State for Defence of the United Kingdom of Great Britain and Northern Ireland
Inventors:
Artemis Stamboulis, Felicity Jane de Cogan, Robert Scott, Anna Frances Acushia Peacock
Abstract: Method of extracting dinitrogen pentoxide (N.sub.2 O.sub.5) from its mixture in nitric acid, which consists of providing a solution of the mixture in an inert organic solvent, stripping out the N.sub.2 O.sub.5 from solution in a carrier gas stream containing ozone, and subsequently condensing the N.sub.2 O.sub.5 out of the gas stream by contact with further inert organic solvent. The presence of ozone suppresses the dissociation of the N.sub.2 O.sub.5 transferred to the gas stream into dinitrogen tetroxide (N.sub.2 O.sub.4). In a preferred embodiment the stripping and absorbing steps take place continuously in adjacent stripping and absorbing columns respectively having organic solvent recirculating through each.
Type:
Grant
Filed:
April 16, 1992
Date of Patent:
November 30, 1993
Assignee:
Secretary of State for Defence in the United Kingdom