Abstract: Compositions, methods, and systems for analyzing the protein corona are described herein, as well as its application in the discovery of advanced diagnostic tools as well as therapeutic targets.
Type:
Grant
Filed:
September 1, 2023
Date of Patent:
April 29, 2025
Assignee:
Seer, Inc.
Inventors:
Hongwei Xia, Lyndal Hesterberg, Michael Figa, Xiaoyan Zhao, Gregory Troiano, William Manning, John Blume, Omid Farokhzad, Matthew McLean, Craig Stolarczyk, Marwin Ko, Theodore Platt
Abstract: Disclosed herein are compositions and methods for assaying for proteins and nucleic acids, in parallel.
Type:
Grant
Filed:
February 24, 2023
Date of Patent:
April 15, 2025
Assignee:
Seer, Inc.
Inventors:
Daniel Hornburg, Michael Figa, Xiaoyan Zhao, Asim S. Siddiqui, Philip Ma, Sangtae Kim, Omid C. Farokhzad, Margaret Donovan, John E. Blume, Theodore Platt, Martin Goldberg, Damian Harris
Abstract: Systems and methods for automated sample preparation and processing of protein corona are described herein, as well as its application in the discovery of advanced diagnostic tools as well as therapeutic agents.
Type:
Grant
Filed:
March 3, 2023
Date of Patent:
March 4, 2025
Assignee:
Seer, Inc.
Inventors:
William Manning, Young Kim, Brandon Kwan-Leong, Hope Liou, Xiaoyan Zhao, Daniel Hornburg, Martin Goldberg
Abstract: Compositions, methods, and systems for analyzing the protein corona are described herein, as well as its application in the discovery of advanced diagnostic tools as well as therapeutic targets.
Type:
Grant
Filed:
March 29, 2021
Date of Patent:
February 11, 2025
Assignee:
Seer, Inc.
Inventors:
Hongwei Xia, Lyndal Hesterberg, Michael Figa, Xiaoyan Zhao, Gregory Troiano, William Manning, John Blume, Omid Farokhzad, Matthew McLean, Craig Stolarczyk, Marwin Ko, Theodore Platt
Abstract: Systems and methods for automated sample preparation and processing of protein corona are described herein, as well as its application in the discovery of advanced diagnostic tools as well as therapeutic agents.
Type:
Grant
Filed:
August 4, 2023
Date of Patent:
July 30, 2024
Assignee:
Seer, Inc.
Inventors:
William Manning, Young Kim, Brandon Kwan-Leong, Hope Liou, Xiaoyan Zhao, Daniel Hornburg, Martin Goldberg
Abstract: Systems and methods for automated sample preparation and processing of protein corona are described herein, as well as its application in the discovery of advanced diagnostic tools as well as therapeutic agents.
Type:
Grant
Filed:
August 4, 2023
Date of Patent:
February 20, 2024
Assignee:
SEER, INC.
Inventors:
William Manning, Young Kim, Brandon Kwan-Leong, Hope Liou, Xiaoyan Zhao, Daniel Hornburg, Martin Goldberg
Abstract: Systems and methods for automated sample preparation and processing of protein corona are described herein, as well as its application in the discovery of advanced diagnostic tools as well as therapeutic agents.
Type:
Grant
Filed:
March 29, 2021
Date of Patent:
April 18, 2023
Assignee:
SEER, INC.
Inventors:
William Manning, Young Kim, Brandon Kwan-Leong, Hope Liou, Xiaoyan Zhao, Daniel Hornburg, Martin Goldberg
Abstract: Compositions, methods, and systems for analyzing the protein corona are described herein, as well as its application in the discovery of advanced diagnostic tools as well as therapeutic targets.
Type:
Grant
Filed:
March 29, 2021
Date of Patent:
August 30, 2022
Assignee:
SEER, INC.
Inventors:
Hongwei Xia, Lyndal Hesterberg, Michael Figa, Xiaoyan Zhao, Gregory Troiano, William Manning, John Blume, Omid Farokhzad, Matthew McLean, Craig Stolarczyk, Marwin Ko, Theodore Platt
Abstract: A business method for use in classifying patient samples. The method includes steps of collecting case samples representing a clinical phenotypic state and control samples representing patients without said clinical phenotypic state. Preferably the system uses a mass spectrometry platform system to identify patterns of polypeptides in said case samples and in the control samples without regard to the specific identity of at least some of said polypeptides. Based on identified representative patterns of the state, the business method provides for the marketing of diagnostic products using representative patterns. The present invention relates to systems and methods for identifying new markers, diagnosing patients with a biological state of interest, and marketing/commercializing such diagnostics. The present invention relates to systems and methods of greater sensitivity, specificity, and/or cost effectiveness.
Type:
Grant
Filed:
September 14, 2018
Date of Patent:
November 5, 2019
Assignee:
Seer, Inc.
Inventors:
John T. Stults, Alfred Greenquist, Alexander Sassi