Patents Assigned to Sekhsaria Chemicals Limited
  • Process for the manufacture of citalopram hydrobromide from 5-bromophthalide
    Patent number: 6812355
    Abstract: A process for the preparation of 1-(4′-fluorophenyl)-1-(3-dimethylamino-propyl)-5-phthalanecarbonitrile of formula (I), or a pharmaceutically acceptable salt thereof, comprising performing two successive Grignard reactions on 5-bromophthalide, wherein the 5-bromophthalide is reacted with the first Grignard reagent in the presence of a Lewis acid, so reducing by-product formation and improving yields.
    Type: Grant
    Filed: October 22, 2002
    Date of Patent: November 2, 2004
    Assignee: Sekhsaria Chemicals Limited
    Inventors: Nandkumar Chodankar, Ajit Bhobhe, Ganesh Mukund Oak, Philip Eappen
  • PROCESS FOR THE MANUFACTURE OF CITALOPRAM HYDROBROMIDE FROM 5-BROMOPHTHALIDE
    Publication number: 20040077870
    Abstract: A process for the preparation of 1-(4′-fluorophenyl)-1-(3-dimethylamino-propyl)-5-phthalanecarbonitrile of formula (I), or a pharmaceutically acceptable salt thereof, 1
    Type: Application
    Filed: October 22, 2002
    Publication date: April 22, 2004
    Applicant: Sekhsaria Chemicals Limited
    Inventors: Nandkumar Chodankar, Ajit Bhobe, G.M. Oak, Philip Eappan