Abstract: Provided are compounds of Formula I: and pharmaceutically acceptable salts and esters thereof. The compounds, compositions, and methods provided are useful for the treatment of virus infections, particularly hepatitis C infections.
Type:
Grant
Filed:
May 21, 2015
Date of Patent:
May 9, 2017
Assignees:
Gilead Sciences, Inc., Selcia Limited
Inventors:
Caroline Aciro, Jean Yves Chiva, David Kenneth Dean, Adrian John Highton, Petr Jansa, Andrew John Keats, Linos Lazarides, Richard Mackman, Karine G. Poullennec, Adam James Schrier, Dustin Scott Siegel, Victoria Alexandra Steadman, Greg Watt
Abstract: Provided are compounds of Formula I: and pharmaceutically acceptable salts and esters thereof. The compounds, compositions, and methods provided are useful for the treatment of Flaviviridae virus infections, particularly hepatitis C infections.
Type:
Grant
Filed:
July 15, 2013
Date of Patent:
January 13, 2015
Assignees:
Gilead Sciences, Inc., Selcia Limited
Inventors:
Todd Appleby, Hans G. Fliri, Andrew J. Keats, Linos Lazarides, Richard L. Mackman, Simon N. Pettit, Karine G. Poullennec, Jonathan Sanvoisin, Victoria A. Steadman, Gregory M. Watt
Abstract: Provided are compounds of Formula I: and pharmaceutically acceptable salts and esters thereof. The compounds, compositions, and methods provided are useful for the treatment of Flaviviridae virus infections, particularly hepatitis C infections.
Type:
Application
Filed:
July 15, 2013
Publication date:
January 23, 2014
Applicants:
Selcia Limited, Gilead Sciences, Inc.
Inventors:
Todd Appleby, Hans G. Fliri, Andrew J. Kaets, Linos Lazarides, Richard L. Mackman, Simon N. Pettit, Karine G. Poullennec, Jonathan Sanvoisin, Victoria A. Steadman, Gregory M. Watt
Abstract: Provided are compounds of Formula I: and pharmaceutically acceptable salts and esters thereof. The compounds, compositions, and methods provided are useful for the treatment of Flaviviridae virus infections, particularly hepatitis C infections.
Type:
Grant
Filed:
December 8, 2011
Date of Patent:
August 20, 2013
Assignees:
Gilead Sciences, Inc., Selcia Limited
Inventors:
Todd Appleby, Hans G. Fliri, Andrew J. Keats, Linos Lazarides, Richard L. Mackman, Simon N. Pettit, Karine G. Poullennec, Jonathan Sanvoisin, Victoria A. Steadman, Gregory M. Watt
Abstract: Provided are compounds of Formula I: and pharmaceutically acceptable salts and esters thereof. The compounds, compositions, and methods provided are useful for the treatment of Flaviviridae virus infections, particularly hepatitis C infections.
Type:
Application
Filed:
December 8, 2011
Publication date:
January 24, 2013
Applicants:
Selcia Limited, Gilead Sciences, Inc.
Inventors:
Todd Appleby, Hans G. Fliri, Andrew J. Keats, Linos Lazarides, Richard L. Mackman, Simon N. Pettit, Karine G. Poullennec, Jonathan Sanvoisin, Victoria A. Steadman, Gregory M. Watt
Abstract: The present invention relates to new therapeutic and prophylactic applications of known compounds of general formula (Ia), novel compounds of formula (Ia) wherein R3 is methyl, and to compositions comprising them, useful as a medication for the topical therapeutic and prophylactic treatment of dermatological and ophthalmic disorders, rheumatoid arthritis and osteoarthritis.
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