Patents Assigned to Selexis SA
  • EXPRESSION SYSTEMS, RECOMBINANT CELLS AND USES THEREOF
    Publication number: 20230193341
    Abstract: A transcriptomic analysis of genes consistently upregulated in high producer clones were each evaluated for their ability to increase the production of a protein of interest. The products of these genes (metabolism influencing products (MIP)), such as actin, Erp27, Erp57, Foxa1, PPAR, Ca3, and Tagap, could be sub-categorized into different functional categories such as signaling, protein folding, cytoskeleton organization and cell survival.
    Type: Application
    Filed: October 23, 2019
    Publication date: June 22, 2023
    Applicant: Selexis SA
    Inventors: Lucille Pourcel, Audrey Berger, Valerie Le Fourn, Severine Fagete, David Calabrese, Alexandre Regamey, Nicolas Mermod, Fabien Palazzoli, Pierre-Alain Girod
  • Matrix attachment regions and methods for use thereof
    Patent number: 7129062
    Abstract: The present invention relates to compositions and methods for transfecting eukaryotic cells with nucleic acid vectors. In particular, the invention relates to the uses of Matrix Attachment Region (MAR) elements to increase stable and transient transfection efficiency.
    Type: Grant
    Filed: January 28, 2002
    Date of Patent: October 31, 2006
    Assignee: Selexis SA
    Inventors: Nicolas Mermod, Monique Zahn-Zabal, Markus Imhof, Philippe Chatellard, Pierre-Alain Girod