Abstract: The invention provides recombinant plasmids containing in DNA sequences coding for human preproparathyroid hormone. The invention further provides microorganisms, for example E. coli, transformed by these plasmids. Finally, the invention also provides a plasmid for insertion into yeast and a transformed yeast in which the plasmid contains DNA coding for parathyroid hormone. Parathyroid hormone is then secreted by the transformed yeast.
Type:
Grant
Filed:
August 14, 1989
Date of Patent:
April 23, 1991
Assignee:
Selmer-Sande, A.S.
Inventors:
Kaare M. Gautvik, Peter Alestrom, Tordis B. Oven, Odd S. Gabrielsen