Abstract: The present invention provides a pharmaceutical composition containing a selenite-containing compound and a pharmaceutically acceptable acid, selected from citric acid, acetic acid, malic acid, carbonic acid, sulfuric acid, nitric acid, hydrochloric acid, fruit acids and mixtures thereof, for use in reducing progression of cervical cell abnormalities in a female patient, wherein the patient is p16-positive and Ki-67-positive at least in a region of the cervix uteri. The composition is applied intravaginally.
Abstract: The invention relates to compositions containing selenite-containing compounds and pharmaceutically acceptable acids, selected from citric acid, acetic acid, malic acid, carbonic acid, sulphuric acid, nitric acid, hydrochloric acid, fruit acids or mixtures thereof, for use for treating cervical inflammations, dysplasia and/or carcinomas. The invention further relates to methods of using such compositions.
Abstract: The use of selenite- or selenate-containing preparations supplemented with pharmaceutically acceptable or food-compatible acids for the preparation of an agent intended for topical or buccal application or mucosal administration is described.
Type:
Grant
Filed:
October 5, 2017
Date of Patent:
March 19, 2019
Assignee:
SELO MEDICAL GMBH
Inventors:
Bodo Kuklinski, Peter Kössler, Norbert Fuchs
Abstract: The use of selenite- or selenate-containing preparations supplemented with pharmaceutically acceptable or food-compatible acids for the preparation of an agent intended for topical or buccal application or mucosal administration is described.
Type:
Grant
Filed:
October 5, 2017
Date of Patent:
March 19, 2019
Assignee:
SELO MEDICAL GMBH
Inventors:
Bodo Kuklinski, Peter Kössler, Norbert Fuchs
Abstract: The invention relates to compositions containing selenite-containing compounds and pharmaceutically acceptable acids, selected from citric acid, acetic acid, malic acid, carbonic acid, sulphuric acid, nitric acid, hydrochloric acid, fruit acids or mixtures thereof, for use for treating cervical inflammations, dysplasia and/or carcinomas. The invention further relates to methods of using such compositions.
Abstract: The use of selenite- or selenate-containing preparations supplemented with pharmaceutically acceptable or food-compatible acids for the preparation of an agent intended for topical or buccal application or mucosal administration is described.
Type:
Application
Filed:
October 5, 2017
Publication date:
February 1, 2018
Applicant:
SELO MEDICAL GMBH
Inventors:
Bodo KUKLINSKI, Peter KÖSSLER, Norbert FUCHS
Abstract: The use of selenite- or selenate-containing preparations supplemented with pharmaceutically acceptable or food-compatible acids for the preparation of an agent intended for topical or buccal application or mucosal administration is described.
Type:
Application
Filed:
October 5, 2017
Publication date:
February 1, 2018
Applicant:
SELO MEDICAL GMBH
Inventors:
Bodo KUKLINSKI, Peter KÖSSLER, Norbert FUCHS
Abstract: The use of selenite- or selenate-containing preparations supplemented with pharmaceutically acceptable or food-compatible acids for the preparation of an agent intended for topical or buccal application or mucosal administration is described.
Type:
Grant
Filed:
October 27, 2010
Date of Patent:
October 31, 2017
Assignee:
SELO MEDICAL GMBH
Inventors:
Bodo Kuklinski, Peter Kössler, Norbert Fuchs
Abstract: The invention relates to compositions containing selenite-containing compounds and pharmaceutically acceptable acids, selected from citric acid, acetic acid, malic acid, carbonic acid, sulphuric acid, nitric acid, hydrochloric acid, fruit acids or mixtures thereof, for use for treating cervical inflammations, dysplasia and/or carcinomas.