Abstract: A peripheral arterial flow obstruction detection system for providing a predictive diagnosis correlating to the diagnosis peripheral arterial disease. The system includes a host computer and a sensor used to detect and measure a physiological signal from a subject's finger or toe, such as the measurement of a signal using photoplethysmography using a PPG sensor. Sensor data is processed and filtered before being used to calculate a number of time-domain and frequency-domain calculations corresponding to the signal waveform. The calculations are used in a predictive model using a multi-faceted algorithm to provide a predictive diagnosis that is displayed on an indicator such as a monitor.

Abstract: Method and apparatus for diagnosing heart failure are disclosed. They include monitoring a subject's pulsatile blood flow with a non-invasive probe during a Valsalva maneuver (VM), processing data therefrom to calculate fall in flow, hear rate changes, Rebound, and heart stroke volume during the VM. Monitored and calculated results are compared to defined thresholds and interpreted and reported. The apparatus takes the form of a pulsatile blood flow probe on a finger or toe or in a mouthpiece facilitating the VM, the mouthpiece optionally including a pressure transducer or digital monometer to ensure that the subject is performing the VM within required pressure and time ranges. The method and apparatus include a controller or digital processor for processing and reporting the results of the monitoring, calculations, comparisons, interpretation, and reporting of the diagnostic results.

Abstract: A lightweight portable probe or transducer containing a transmissive or reflective electro-optical emitter and receptor in the infrared spectrum is fitted on a subject's finger or toe. Associated electronics energize and monitor the probe, detect cardio-rhythmic fluctuations therefrom, and process digital data over a prescribed window to produce a non-invasive, qualitative or quantitative measure of the subject's circulation. In accordance with one embodiment of the invention, a simple tri-color LED array is used to indicate the subject's circulation as being normal, reduced, or borderline.