Patents Assigned to Semorex Inc.
  • Publication number: 20160313356
    Abstract: Methods and kits which utilize a conjugate, preferably an adduct, of ergosterol for determining the presence or level of a broad spectrum of ergosterol-containing organisms (e.g., fungi) in various substrates are disclosed. These methods and kits can be used to accurately and efficiently diagnose a subject having a fungal infection, particularly invasive fungal infection, and to accurately and efficiently detect the presence of fungi and other ergosterol-containing organisms in other substrates. Antibodies and other compounds (e.g., molecularly imprinted polymers) that are capable of selectively binding to ergosterol or to an ergosterol-containing conjugate and methods of producing same are also disclosed.
    Type: Application
    Filed: July 4, 2016
    Publication date: October 27, 2016
    Applicant: Semorex Inc.
    Inventors: Bernard S. GREEN, Inna TZOMIK, Rina ARAD-YELLIN
  • Patent number: 9383373
    Abstract: Methods and kits which utilize a conjugate, preferably an adduct, of ergosterol for determining the presence or level of a broad spectrum of ergosterol-containing organisms (e.g., fungi) in various substrates are disclosed. These methods and kits can be used to accurately and efficiently diagnose a subject having a fungal infection, particularly invasive fungal infection, and to accurately and efficiently detect the presence of fungi and other ergosterol-containing organisms in other substrates. Antibodies and other compounds (e.g., molecularly imprinted polymers) that are capable of selectively binding to ergosterol or to an ergosterol-containing conjugate and methods of producing same are also disclosed.
    Type: Grant
    Filed: November 15, 2006
    Date of Patent: July 5, 2016
    Assignee: Semorex Inc.
    Inventors: Bernard S. Green, Inna Tzomik, Rina Arad-Yellin
  • Publication number: 20090111129
    Abstract: Methods and kits which utilize a conjugate, preferably an adduct, of ergosterol for determining the presence or level of a broad spectrum of ergosterol-containing organisms (e.g., fungi) in various substrates are disclosed. These methods and kits can be used to accurately and efficiently diagnose a subject having a fungal infection, particularly invasive fungal infection, and to accurately and efficiently detect the presence of fungi and other ergosterol-containing organisms in other substrates. Antibodies and other compounds (e.g., molecularly imprinted polymers) that are capable of selectively binding to ergosterol or to an ergosterol-containing conjugate and methods of producing same are also disclosed.
    Type: Application
    Filed: November 15, 2006
    Publication date: April 30, 2009
    Applicant: Semorex Inc.
    Inventors: Bernard S. Green, Inna Tzomik, Rina Arad-Yellin
  • Patent number: 6638498
    Abstract: Improved molecularly imprinted polymers (MIPs) with both higher and more specific binding capacity for particular bile acids and/or salts, including the synthesis of such MIPs, the compounds themselves, and specific applications thereof. As an example of a particularly preferred specific application of these compounds, the present invention encompasses the use of the MIPs as sequestrants in the gastrointestinal tract, particularly in order to bind and therefore remove toxins from the gastrointestinal tract. In addition, the present invention is also useful for treatment of various diseases which are related to, and/or characterized by, an effect of bile acids and salts, such as atherosclerosis, liver disease and various diseases of the gastrointestinal tract. The MIP compounds of the present invention are also useful for combination therapy with other medications and for diagnosis and monitoring of diseases.
    Type: Grant
    Filed: June 29, 2001
    Date of Patent: October 28, 2003
    Assignee: Semorex Inc.
    Inventors: Bernard S. Green, Morris Priwler