Patents Assigned to SENDA BIOSCIENCES, INC.
  • PYRIDOPYRIMIDINONE DERIVATIVES AS AHR ANTAGONISTS
    Publication number: 20230295152
    Abstract: The present disclosure relates to compounds of formula (Ia) and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising the same, methods of preparing the same, intermediate compounds useful for preparing the same, and methods for treating or prophylaxis of diseases, in particular cancer or conditions with dysregulated immune responses or other disorders associated with aberrant AHR signaling. These compounds may also be useful in treating cancer when administered in combination with at least one additional therapy.
    Type: Application
    Filed: November 20, 2020
    Publication date: September 21, 2023
    Applicant: SENDA BIOSCIENCES, INC.
    Inventors: Alessandra BARTOLOZZI, John Robert PROUDFOOT, Timothy BRIGGS, John MANCUSO, Karunakar Reddy BONEPALLY, Patrick BUREAU, Tianlin GUO, Maxence BOS, Anna BLOIS, Bernard LANTER, Steven John TAYLOR, Leonard BUCKBINDER, Francesca BARONE