Patents Assigned to Senex Biotechnology
  • CDKI pathway inhibitors and uses thereof
    Patent number: 8598344
    Abstract: The invention relates to compounds for inhibiting the Cyclin-Dependent Kinase Inhibitor (CDKI) pathway. More particularly, the invention relates to compounds for inhibiting the CDKI pathway for studies of and intervention in senescence-related and other CDKI-related diseases.
    Type: Grant
    Filed: November 30, 2010
    Date of Patent: December 3, 2013
    Assignee: Senex Biotechnology
    Inventors: Donald C. Porter, Igor B. Roninson, Mark P. Wentland
  • High-content screening for drugs against cancer and age-related diseases
    Patent number: 8592147
    Abstract: The invention relates to methods for high-throughput screening for compounds that modulate cell growth or promoter activity. The invention provides the use of cell lines with properly regulated promoter-reporter expression, suitable for high-throughput screening. More particularly, the invention relates to such screening to identify compounds that affect cell growth and/or that modulate the effect of cell cycle arrest on the function of a promoter that is responsive to cell cycle inhibition.
    Type: Grant
    Filed: January 12, 2006
    Date of Patent: November 26, 2013
    Assignee: Senex Biotechnology
    Inventors: Bey-Dih Chang, Igor B. Roninson