Patents Assigned to SenoRx, Inc.
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Patent number: 9237937Abstract: A method of marking a biopsy site within a patient's body includes providing a delivery tube having a plunger; carrying a quantity of an ultrasound-detectable bio-resorbable particulate material in the delivery tube distal to the plunger, the ultrasound-detectable bio-resorbable particulate material having a particle size between about 200 microns and about 500 microns and having internal bubble cavities having a size of at least 50 microns; and depressing the plunger for depositing the quantity of the ultrasound-detectable bio-resorbable particulate material at the biopsy site.Type: GrantFiled: February 20, 2015Date of Patent: January 19, 2016Assignee: SenoRX, Inc.Inventors: Fred H. Burbank, Paul Lubock, Michael L. Jones
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Patent number: 9216012Abstract: A medical device for localization of tissue at a target site in a patient's body includes a tube having a distal end, a proximal end, and a longitudinal axis. The medical device is configured for placement of the distal end at the target site. A fixation device is disposed on the distal end. The affixation device is configured to mechanically fix the distal end of the medical device to tissue at the target site.Type: GrantFiled: July 6, 2012Date of Patent: December 22, 2015Assignee: SenoRx, IncInventors: Fred H. Burbank, Paul Lubock, Michael L. Jones, Richard L. Quick
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Patent number: 9204866Abstract: The invention is directed to a system and device for separating and collecting a tissue specimen from a target site within a patient. The device includes a probe component with an elongated tubular section, a penetrating distal tip and a tissue receiving aperture in the distal end of the tubular section proximal to the distal tip, and a tissue cutting member which is slidably disposed within the probe member to cut a tissue specimen drawn into the interior of the device through the aperture by applying a vacuum to the inner lumen of the tissue cutting member. The device also has a driver component to which the probe component is releasably secured. The driver has a drive member for adjusting the orientation of the tubular section and thus the aperture therein and one or more drive members for moving the tissue cutting member within the tubular section to sever a tissue specimen from tissue extending into the interior of the tubular section through the aperture.Type: GrantFiled: June 4, 2010Date of Patent: December 8, 2015Assignee: SenoRx, Inc.Inventors: Martin V. Shabaz, Richard L. Quick, Frank R. Louw, Paul Lubock, Jason H. Safabash
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Patent number: 9149341Abstract: A method for treating a site within a patient from which tissue has been removed includes providing at least one press-formed marker body formed of polysaccharide and a suitable binder; and placing the at least one of the press-formed marker body within the site where tissue has been removed so as to provide hemostasis therein.Type: GrantFiled: November 21, 2011Date of Patent: October 6, 2015Assignee: SenoRx, IncInventors: Michael L. Jones, Paul Lubock
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Patent number: 9095325Abstract: The invention is directed to tissue cutting members and biopsy devices with such tissue cutting member for separating a tissue specimen from a patient's body at a target site. The tissue cutting member is slidably disposed within an inner lumen of an elongated probe member of the biopsy device to cut a tissue specimen drawn into the interior of an outer cannula of the biopsy device through a tissue receiving aperture in the probe. The tissue cutting member has a tubular distal portion with a distal tip having an outer tissue cutting edge, an inner tissue receiving aperture, and a longitudinally oriented opening with a closed proximal end and open distal end which opens to the inner tissue receiving aperture to facilitate flaring of the distal tubular portion. The cutting member has at least one opening in a wall of the tubular portion to maintain a vacuum during use.Type: GrantFiled: May 22, 2006Date of Patent: August 4, 2015Assignee: SENORX, INC.Inventors: Paul Lubock, Frank R. Louw, Richard L. Quick
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Patent number: 9055926Abstract: One embodiment having features of the invention is directed to a guide block for an MRI device which has a block body with a proximal face, a distal face, and four parallel passageways extending between the two faces. The first passageway is centrally disposed, the second passageway is disposed vertical or horizontal to the first, the third passageway is located diagonal to the first and has a longitudinal opening in fluid communication with the first passageway, and the fourth passageway is diagonal to the first and in an opposite side of the body from the third passageway. In an alternative embodiment the guide block has at least one passageway that is not parallel to the longitudinal axis.Type: GrantFiled: May 14, 2010Date of Patent: June 16, 2015Assignee: SenoRx, Inc.Inventor: Martin V. Shabaz
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Patent number: 9044215Abstract: The invention is directed to a system and device for separating and collecting a tissue specimen from a target site within a patient. The device includes a probe component with an elongated tubular section, a penetrating distal tip and a tissue receiving aperture in the distal end of the tubular section proximal to the distal tip, and a tissue cutting member which is slidably disposed within the probe member to cut a tissue specimen drawn into the interior of the device through the aperture by applying a vacuum to the inner lumen of the tissue cutting member. The device also has a driver component to which the probe component is releasably secured. The driver has a drive member for adjusting the orientation of the tubular section and thus the aperture therein and one or more drive members for moving the tissue cutting member within the tubular section to sever a tissue specimen from tissue extending into the interior of the tubular section through the aperture.Type: GrantFiled: August 25, 2008Date of Patent: June 2, 2015Assignee: SenoRx, Inc.Inventors: Martin V. Shabaz, Richard L. Quick, Frank R. Louw, Paul Lubock, Jason H. Safabash
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Patent number: 9044162Abstract: A marker delivery device includes an elongated delivery cannula which has a distal end section, an inner lumen and a discharge opening in the distal end section in communication with the inner lumen. At least one elongated fibrous marker body is slidably disposed within the inner lumen of the elongated delivery cannula. The at least one elongated fibrous marker body includes a plurality of bioabsorbable polymeric strands. The strands are compressed to a compressed configuration and bound together in the compressed configuration with a polymer binding agent prior to insertion into the elongated delivery cannula.Type: GrantFiled: January 25, 2013Date of Patent: June 2, 2015Assignee: SenoRx, Inc.Inventors: Michael L. Jones, Paul Lubock, John Merritt
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Patent number: 9039763Abstract: An implant for marking an area within a living body includes a matrix material and a marking material. The implant is formable to fit the shape and size of a cavity in the human body. The implant is configured to support tissue surrounding the cavity and to allow in-growth of fibrous tissue into and replace at least a portion of the matrix material.Type: GrantFiled: January 28, 2014Date of Patent: May 26, 2015Assignee: SenoRx, Inc.Inventor: John D. Corbitt, Jr.
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Patent number: 8965486Abstract: The invention provides materials, devices and methods for marking biopsy sites for a limited time. The biopsy-marking materials are ultrasound-detectable bio-resorbable powders, with powder particles typically between about 20 microns and about 800 microns in maximum dimension, more preferably between about 300 microns and about 500 microns. The powders may be formed of polymeric materials containing cavities sized between about 10 microns and about 500 microns, and may also contain binding agents, anesthetic agents, hemostatic agents, and radiopaque markers. Devices for delivering the powders include tubes configured to contain the powders and to fit within a biopsy cannula, the powders being ejected by action of a syringe. Systems may include a tube containing powder, and a syringe containing sterile saline. The tube may be configured to fit within a biopsy cannula such as a Mammotome® or SenoCor 360™ cannula.Type: GrantFiled: December 6, 2013Date of Patent: February 24, 2015Assignee: SenoRx, Inc.Inventors: Fred H. Burbank, Paul Lubock, Michael L. Jones
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Patent number: 8915864Abstract: The invention is directed to a system and method for separating and collecting one or more tissue specimens from a target site within a patient and flushing the specimen to remove blood, debris and the like before the specimen is removed from the biopsy device. The flow of flushing fluid to the tissue collector is preferably controlled to coincide with delivery of one or more specimens to the collecting tray or basket of the device or after the receipt of the specimen within the tissue collector to ensure that the fluid is applied to a fresh specimen. The tissue tray or basket within the tissue collector has an open or foraminous portion to facilitate removal of fluid, such as the applied fluid and blood, and other debris from the tissue specimens on the tray. Vacuum is provided within the tissue collector, preferably under the tray to remove fluid and debris from the collector interior.Type: GrantFiled: November 21, 2012Date of Patent: December 23, 2014Assignee: SenoRx, Inc.Inventors: Richard L. Quick, Martin V. Shabaz, Frank R. Louw, Paul Lubock, Jason H. Safabash
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Patent number: 8882760Abstract: A medical device system and method provide an RF electrosurgical generator coupled to an electrosurgical electrode via a patient box disposed in close proximity to the patient. An RF signal is delivered from the generator to the patient box where signal power is increased and the RF signal delivered to the electrosurgical electrode. The patient box is coupled to the electrosurgical electrode by a short cable capable of carrying an HV, high frequency 5 MHz signal without leakage. An electrical characteristic associated with the electrosurgical electrode is monitored and a desired RF power output and duty cycle maintained by adjusting DC input voltage applied to an RF amplifier, responsive to the monitoring. The system determines when the electrosurgical cutting electrode has started cutting and switches from a start mode to a run mode having a different RF duty cycle and a reduced RF power output controlled by a servo system.Type: GrantFiled: August 27, 2008Date of Patent: November 11, 2014Assignee: SenoRx, Inc.Inventors: Derek Daw, James Huntington Dabney
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Patent number: 8880154Abstract: An intracorporeal marker includes a fibrous unitary marker body having bioabsorbable fibers compressed into a compressed configuration, and bound in the compressed configuration by a polymer binding agent. The intracorporeal marker may be incorporated into an intracorporeal marker delivery device having a delivery cannula which has a distal tip, an inner lumen and a discharge opening in communication with the inner lumen. The compression and binding occur prior to insertion of the fibrous unitary marker body into the inner lumen of the delivery cannula. The fibrous unitary marker body is slidably disposed within and pushable through the inner lumen of the elongated delivery cannula proximal to the discharge opening.Type: GrantFiled: July 19, 2013Date of Patent: November 4, 2014Assignee: SenoRx, Inc.Inventors: Michael L. Jones, Paul Lubock, Lloyd H. Malchow
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Publication number: 20140303515Abstract: A guide block configured to be inserted into an opening of a grid-like breast receiving pressure plate to guide a tissue-removing device to a desired location within a patient's breast. The guide block includes a body having a body length between a proximal face and a distal face. The body length has a plurality of sides configured in a polygonal arrangement that corresponds to a shape of the opening in the grid-like breast receiving pressure plate. Each of a first guide passageway and a second guide passageway extends within the polygonal arrangement. The second guide passageway is coextensive with and configured to overlap the first guide passageway in a direction of extent of the plurality of sides to form a longitudinal opening between the first guide passageway and the second guide passageway that extends from the proximal face to the distal face.Type: ApplicationFiled: May 12, 2014Publication date: October 9, 2014Applicant: SenoRx, Inc.Inventor: Martin V. Shabaz
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Publication number: 20140239528Abstract: In one form, the invention is directed to a method for forming a porous implant suitable for a cavity from which tissue has been removed, including mixing soluble alginate and a radiopaque imaging agent with water; incorporating a gas or a pore forming agent into the alginate-water mixture; transferring the alginate-water mixture with the gas or the pore forming agent into a mold to form the mixture into a solid body of desired shape; removing the water from the body; and converting at least part of the soluble alginate to a less soluble alginate. In another form, the invention includes forming a mixture by mixing about 0.5 percent to about 4 percent by weight chitosan into an acidified aqueous solution containing 1 percent to 25 percent by weight acetic acid, along with about 0.5 percent to about 5 percent by weight of a powdered radiopaque imaging agent.Type: ApplicationFiled: May 7, 2014Publication date: August 28, 2014Applicant: SenoRx, Inc.Inventors: Amit Govil, Michael L. Jones, Paul Lubock
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Publication number: 20140243675Abstract: The invention is directed biopsy site markers and methods of marking a biopsy site, so that the location of the biopsy cavity is readily visible by conventional imaging methods, particularly by ultrasonic imaging. The biopsy site markers of the invention have high ultrasound reflectivity, presenting a substantial acoustic signature from a small marker, so as to avoid obscuring diagnostic tissue features in subsequent imaging studies, and can be readily distinguished from biological features. The several disclosed embodiments of the biopsy site marker of the invention have a high contrast of acoustic impedance as placed in a tissue site, so as to efficiently reflect and scatter ultrasonic energy, and preferably include gas-filled internal pores. The markers may have a non-uniform surface contour to enhance the acoustic signature. The markers have a characteristic form which is recognizably artificial during medical imaging.Type: ApplicationFiled: May 2, 2014Publication date: August 28, 2014Applicant: SenoRX, Inc.Inventors: Fred H. Burbank, Paul Lubock, Michael L. Jones, Richard L. Quick, Frank R. Louw, Stephen A. DeSantis
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Patent number: 8795195Abstract: A graphical user interface is disclosed for a tissue biopsy system having a tissue cutting member adapted for cutting one or more tissue specimens from tissue at a target site within a patient. The graphical user interface includes a first GUI area representing a first region of the target site from which the tissue cutting member has separated one or more tissue specimens. The graphical user interface further includes a second GUI area, visually distinguishable from the first GUI area, representing a second region from which the tissue cutting member may separate one or more additional tissue specimens from tissue at the target site.Type: GrantFiled: November 22, 2005Date of Patent: August 5, 2014Assignee: SenoRx, Inc.Inventors: Derek Daw, Frank R. Louw, Paul Lubock, Richard L. Quick, Martin V. Shabaz
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Patent number: 8784433Abstract: An intracorporeal marker delivery device includes a delivery tube which has a distal tip, a discharge orifice and an inner bore extending to the discharge orifice. A plug is releasably secured within the inner bore. The plug may itself serve as a marker, and may be the sole marker. Markers may be positioned proximal to the plug, and may be detectable by ultrasound, X-ray, magnetic resonance imaging, and other imaging devices, and may include bioactive elements.Type: GrantFiled: April 27, 2012Date of Patent: July 22, 2014Assignee: SenoRx, Inc.Inventors: Paul Lubock, Jason H. Safabash, Martin Shabaz, John Merritt
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Patent number: 8764741Abstract: A high frequency electrosurgical power generator configured to produce electrical power at a frequency of about 1 to about 14 MHz and preferably having an essentially sinusoidal waveform with a voltage level up to 1,000 Vrms, and a current level up to 5 Amps. The output of the high frequency electrosurgical power generator is connected to an electrosurgical tool configured to receive the voltage and current produced by the electrosurgical power generator and deliver the voltage and current to an electrosurgical site. The output of the electrosurgical generator preferably is an essentially sinusoid waveform with a frequency between about 3 MHz and about 8 MHz, up to about 700 volts rms, up to about 2 amps, with a total power of up to 1,000 watts.Type: GrantFiled: August 8, 2007Date of Patent: July 1, 2014Assignee: Senorx, Inc.Inventors: James Huntington Dabney, Richard L. Quick, Conrad Sawicz, Paul Lubock, Dan Kussman
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Publication number: 20140180163Abstract: A device and method for treatment of a tissue specimen disposed in surrounding tissue includes isolating the tissue specimen from the surrounding tissue by using a separating device to sever and separate the tissue specimen from the surrounding tissue; damaging the isolated tissue specimen with a tissue specimen damaging device; and using an encapsulating device to encapsulate the isolated and damaged tissue specimen, the encapsulating device configured for operation independent from the separating device and the tissue specimen damaging device.Type: ApplicationFiled: January 27, 2014Publication date: June 26, 2014Applicant: SenoRx, Inc.Inventors: Fred H. Burbank, Paul Lubock