Abstract: A drug delivery device (1) comprising a delivery unit (2) receiving a drug cartridge (3) containing a drug to be administered to a patient in need thereof, the delivery unit comprising a subcutaneous delivery mechanism (7) including a needle (24), a needle support (8) to which the needle is mounted, and a needle actuation mechanism (9) configured to move the needle from a retracted position within a housing (5) of the delivery unit (2), to an extended delivery position where the needle projects through a base wall (14) of the housing. The needle actuation mechanism comprises a rotary actuator (10) configured to engage an engagement lever (11) coupled to the needle support (8) for translating the needle support between retracted and extended delivery positions.

Abstract: A drug delivery device comprising a delivery unit (2) including an internal reservoir (8), a subcutaneous delivery mechanism (6), a pump for pumping liquid from the internal reservoir to the subcutaneous delivery system, and a liquid filling mechanism (12) configured for injecting liquid from an external vial (16) or reservoir into the internal reservoir. The liquid filling mechanism comprises a filling port (14) and a valve mechanism (18) selectively operable to: open a first fluid path (54) extending from the filling port to the internal fluid reservoir and close a second fluid path (56) extending from the internal reservoir to the subcutaneous delivery member, or close the first fluid path and open the second fluid path.

Abstract: A subcutaneous delivery mechanism for a drug delivery device (1), comprising a needle (10), a needle holder (12) holding the needle (10), and a needle actuation mechanism (20) configured to actuate in translation the needle holder (12) to move the needle (10) from a retracted position to an extended delivery position. The needle actuation mechanism (20) comprises a first lever (30) pivotally mounted on a first support member (33) and a rotary actuator (22) rotatably mounted on a second support member (43). The first lever (30) is configured to engage the rotary actuator (22). The needle actuation mechanism (20) also comprises a second lever (40) pivotally mounted on the second support member (43) or around a circumferential outer rim (24) of the rotary actuator (22). The first and second levers (30, 40) are coupled to each other such that rotation of the first lever (30) causes rotation of the second lever (40).

Abstract: A micropump including: a stator (4); a rotor (6) slidably and rotatably mounted at least partially in the stator, the rotor comprising a first axial extension (24) having a first diameter (D1) and a second axial extension (26) having a second diameter (D2) greater than the first diameter; a first valve (V1) formed by a first valve seal (18) mounted on the stator around the first axial extension, in conjunction with a first channel (42) in the rotor that is configured to allow liquid communication across the first valve seal when the first valve is in an open position; a second valve (V2) formed by a second valve seal (20) mounted on the stator around the second axial extension, in conjunction with a second channel (44) in the rotor that is configured to allow liquid communication across the second valve seal when the second valve is in an open position; a pump chamber (8) formed between the rotor and stator and between the first valve seal and second valve seal, and a cam system comprising a cam track (22, 22

Abstract: A pump includes: a stator (4), a rotor (6) slidably and rotatably mounted at least partially in the stator, the rotor comprising a first axial extension (24) having a first diameter (D1) and a second axial extension (26) having a second diameter (D2) greater than the first diameter, a first valve (V1) formed by a first valve seal (18) mounted on the stator around the first axial extension, in conjunction with a first channel (42) in the rotor that is configured to allow liquid communication across the first valve seal when the first valve is in an open position, a second valve (V2) formed by a second valve seal (20) mounted on the stator around the second axial extension, in conjunction with a second channel (44) in the rotor that is configured to allow liquid communication across the second valve seal when the second valve is in an open position; a pump chamber (8) formed between the rotor (6) and stator (4) and between the first valve seal (18) and second valve seal (20); and a pump chamber seal (22) circum

Abstract: A pump (2) comprising a stator (4) and a rotor (6) axially and rotatably movable relative to the stator, the stator comprising a rotor shaft receiving cavity (18), an inlet (14) and an outlet (16) fluidly connected to the rotor shaft receiving cavity (18), the rotor comprising a shaft (24) received in the rotor shaft receiving cavity (18). The rotor shaft (24) comprises a cavity (39) receiving a piston portion (12) of the stator therein to form a piston chamber (42), a seal (44) mounted between the piston portion (12) and inner sidewall of the cavity (39) to sealingly close an end of the piston chamber (42).

Abstract: A pump including: a stator (4), a rotor (6) slidably and rotatably mounted at least partially in the stator, the rotor comprising a first axial extension (24) having a first diameter (D1) and a second axial extension (26) having a second diameter (D2) greater than the first diameter, a first valve (V1) formed by a first valve seal (18) mounted on the stator around the first axial extension, in conjunction with a first channel (42) in the rotor that is configured to allow liquid communication across the first valve seal when the first valve is in an open position, a second valve (V2) formed by a second valve seal (20) mounted on the stator around the second axial extension, in conjunction with a second channel (44) in the rotor that is configured to allow liquid communication across the second valve seal when the second valve is in an open position, and a pump chamber (8) formed between the rotor and stator and between the first valve seal and second valve seal.

Abstract: A delivery unit (2) of a drug delivery device (1), the delivery unit (2) comprising a subcutaneous delivery mechanism (9) having a subcutaneous delivery member (92), and a subcutaneous delivery member actuation mechanism (10) being operable to move the subcutaneous delivery member (92) between a retracted position and an extended position. The actuation mechanism (10) comprises a rotary member (102) having an engagement member (104) rotatable relative a support member (14), and an actuator (106) comprising a pivot portion (10A) and an engagement portion (10B) pivotally connected to the support member via the pivot portion. The engagement member (104) and engagement portion (10B) are configured to engage upon rotation of the rotary member to pivot the actuator between first and second positions and to thereby move the subcutaneous delivery member (92) between the corresponding retracted and extended positions. In an embodiment, the needle actuation mechanism may comprise a reuse protection.

Abstract: The invention relates to a liquid storage and delivery system including a reusable housing (8) comprising a control and drive unit, a container (2), a pump module (4) fluidically connected to the container (2), and a coupling system (6) configured for removably coupling the pump module (4) to the control and drive unit (6). The pump module comprises a pump engine (20), a pump outlet (22), and a transmission input coupling (18) coupled to the pump engine (20). The housing comprising the control and drive unit also comprises a pump drive (34) configured to engage the transmission input coupling (18) of the pump module (4) when the pump module (4) is coupled to the housing comprising the control and drive unit. The container (2) is in the form of a flexible pouch and the pump module (4) is permanently integrated with the flexible pouch and forms therewith a disposable unit.

Abstract: A delivery unit (2) of a drug delivery device (1), the delivery unit (2) comprising a subcutaneous delivery mechanism (9) having a subcutaneous delivery member (92), and a subcutaneous delivery member actuation mechanism (10) being operable to move the subcutaneous delivery member (92) between a retracted position and an extended position. The actuation mechanism (10) comprises a rotary member (102) having an engagement member (104) rotatable relative a support member (14), and an actuator (106) comprising a pivot portion (10A) and an engagement portion (10B) pivotally connected to the support member via the pivot portion. The engagement member (104) and engagement portion (10B) are configured to engage upon rotation of the rotary member to pivot the actuator between first and second positions and to thereby move the subcutaneous delivery member (92) between the corresponding retracted and extended positions. In an embodiment, the needle actuation mechanism may comprise a reuse protection.