Abstract: An analysing apparatus comprises a fluid container defining a sample chamber. A sensor having a transparent body with a nanostructured surface is coupled to the fluid container such that the nanostructured surface is exposed to the sample chamber. An excitation and detection apparatus directs a beam of incident polarised electromagnetic radiation onto the reverse face of the body at the Brewster angle, causing no or substantially no reflection of the polarised radiation from the reverse face. The beam of reflected radiation emerges from the reverse face after reflection from the nanostructured surface. The apparatus is simpler and cheaper in comparison with known alternatives that use ATR prisms to create ATR of the light to excite a planar surface.

Abstract: A flexure structure comprising the unitary combination of three modified S-shaped beams arranged in parallel and sharing common top and bottom structures. The outside beams are oriented alike in one direction while the inside or center beam is oriented in the opposite direction. The outside edge surfaces of the beams are flat and are instrumented with strain sensors connected in bridge circuits.

Abstract: High-resolution thermopile infrared sensor array having a plurality of parallel signal processing channels for the signals of a sensor array and a digital port for serially emitting the signals. Each signal processing channel comprises at least one analog to digital converter and is assigned a memory for storing the results of the analog to digital converters. Power consumption of the infrared sensor array is reduced in the case of a sensor array with at least 16 rows and at least 16 columns, in that no more than 8 or 16 pixels are connected to a signal processing channel. The number of signal processing channels corresponds to at least 4 times the number of rows. Some of the signal processing channels are disposed in the intermediate space between the pixels and others are disposed in an outer edge region of the sensor chip surrounding the sensor array along with other electronics.

Abstract: The present disclosure relates to methods and devices for amplifying a plurality of targets in a single PCR run while distinguishing between clinically relevant amplification and amplification from other sources such as from background contamination. The methods and devices further enable discrimination between gram-positive, gram-negative and fungal infections as wells as identify antimicrobial resistance genes. When applying the methods and devices of the invention, the species or genus of an infection(s), and genus of a fungal co-infection(s) or category of bacterial (gram-positive or negative) co-infection(s) are identified. Species identification of co-infections can also be achieved. Further, when applying the methods and devices of the invention, organisms which are likely to be contaminating organisms from a blood draw are identified.

Abstract: The present disclosure relates to a thin film sensor element for determining and/or monitoring temperature. For this purpose, a resistive structure is provided, which is arranged in a resistive region on a substrate. The resistive structure is so formed that a first section of the resistive structure branches at a first reference point into two branches, and that a second section of the resistive structure branches at a second reference point into two other branches. In a contact region, the four branches are connected with four intermediate conductors in four contact areas, which are insulated from one another. In this way, the thin film sensor element is a real four conductor sensor element, wherein the reference points of the four conductor circuit lie within the resistive region. The resistance thermometer with the thin film sensor element of the invention is distinguished by a high accuracy.

Abstract: A sensor and system for monitoring integrity of a waterproofing system membrane. A geomembrane integrity monitoring system includes control means 18 and a plurality of sensors 20. The sensors 20 are electrically isolated from each other and in electrical communication to the control means 18. The sensors 20 have a sheet form.

Abstract: A bus-compatible sensor element includes a converter generating a digital measurement signal, a first data input receiving an input data, a first data output for outputting an output data, a first clock input receiving a first clock signal, a slave select connection receiving an activation signal, and a 1-bit shift register. The 1-bit shift register includes a shift register data input, a shift register output, and a second clock input. The shift register output is connected to the slave select connection to activate the sensor element in response to the activation signal present at the shift register data input.

Abstract: A highly configurable controller is described that includes a number of different types of control mechanisms that emulate a wide variety of conventional control mechanisms using pressure and location sensitive sensors that generate high-density control information which may be mapped to the controls of a wide variety of devices and software.

Abstract: An improved heterostructure for an optoelectronic device is provided. The heterostructure includes an active region, an electron blocking layer, and a p-type contact layer. The p-type contact layer and electron blocking layer can be doped with a p-type dopant. The dopant concentration for the electron blocking layer can be at most ten percent the dopant concentration of the p-type contact layer. A method of designing such a heterostructure is also described.

Abstract: An apparatus for detecting a magnetic security feature of a valuable document including a transport apparatus configured to transport the valuable document through the apparatus, sensors configured as magnetic sensors and having at least two security feature sensors and at least one compensation sensor, and an evaluation unit configured to receive the signals output by the sensors, wherein the sensors are arranged and configured in a line parallel to the transport plane and transversely with respect to the direction of transport. The sensors are arranged at a distance from the transport plane such that the distance of the security feature sensors is configured to capture a security feature by means of at least one of the security feature sensors, and that the distance of the compensation sensor is configured not to capture a security feature by means of the compensation sensor.

Abstract: An apparatus, system, and method for monitoring a person suffering from a chronic medical condition predicts and assesses physiological changes which could affect the care of that subject. Examples of such chronic diseases include (but are not limited to) heart failure, chronic obstructive pulmonary disease, asthma, and diabetes. Monitoring includes measurements of respiratory movements, which can then be analyzed for evidence of changes in respiratory rate, or for events such as hypopneas, apneas and periodic breathing. Monitoring may be augmented by the measurement of nocturnal heart rate in conjunction with respiratory monitoring. Additional physiological measurements can also be taken such as subjective symptom data, blood pressure, blood oxygen levels, and various molecular markers. Embodiments for detection of respiratory patterns and heart rate are disclosed, together with exemplar implementations of decision processes based on these measurements.

Abstract: A calibration electrode for calibrating a reference system of an electrochemical sensor, such as a potentiometric sensor or an ion selective electrode. The calibration electrode has an active surface comprising redox functionalities. The redox functionalities set the pH of a reference solution proximal to the calibration electrode. A voltammetric signal is applied to the calibration electrode to produce a response that is determined by the set pH. The response of the calibration electrode to the voltammetric signal is used to calibrate/adjust a reference potential produced by a reference electrode of the reference system of the electrochemical sensor. This calibration corrects the detrimental effect of reference electrode drift.

Abstract: An aspect of the invention is directed to a system of both atmospheric and underwater sensors for measuring pressure waves from a noise source. A system of pressure sensors can be formed to determine the location of an external noise source, whether in air or underwater. The system includes at least two arrays consisting of pressure sensors, including at least one atmospheric pressure sensor and at least one underwater pressure sensor, such as a hydrophone. Each sensor may be a seven-fiber intensity modulated fiber optic pressure sensor. The system includes an analog to digital converter for digitizing the pressure data received from each sensor and a processor which processes the received signals to calculate an approximate location of the noise source based upon the pressure signals received by the sensors at different times of arrival. The system can provide this capability in remote applications due to its low power requirements.

Abstract: The invention relates to a thermopile infrared individual sensor in a housing that is filled with a gaseous medium having optics and one or more sensor chips with individual sensor cells with infrared sensor structures with reticulated membranes, the infrared-sensitive regions of which are spanned by, in each case, at least one beam over a cavity in a carrier body with good thermal conduction. The object of the invention consists of specifying a thermopile infrared sensor using monolithic Si-micromechanics technology for contactless temperature measurements, which, in the case of a sufficiently large receiver surface, outputs a high signal with a high response speed and which can operated in a gaseous medium with normal pressure or reduced pressure and which is producible in mass produced numbers without complicated technology for sealing the housing.

Abstract: The disclosure relates to a method for determining a hydrodynamic size of an object, such as a nano-sized object, said method comprising the steps of: —providing a fluid interface, —linking said object to said fluid interface thereby providing a linked object, whereby the movement of said linked object is restricted by virtue of being linked to said fluid interface, —providing and determining a hydrodynamic shear force that acts on said linked object, —tracking the movement of said linked object, and —calculating the hydrodynamic size of the object using the Einstein-Smoluchowski relation.

Abstract: A method of assembling a photodetector assembly includes depositing bumps on a read out integrated circuit (ROIC) without depositing bumps on a photodiode array (PDA). The method includes assembling the PDA and ROIC together wherein each bump electrically interconnects the ROIC with a respective contact of the PDA. A photodetector assembly includes a PDA. A ROIC is assembled to the PDA, wherein the ROIC is electrically interconnected with the PDA through a plurality of electrically conductive bumps. Each bump is confined within a respective pocket between the ROIC and a respective contact of the PDA. The disclosed methods can enable focal plane array manufacturers to achieve low-cost production of ultra-fine pitch, large format imaging arrays.

Abstract: The illustrated embodiments include a method of operating a SAW sensor to detect a sample in a fluid which includes the steps of: providing a SAW sensor with a functionalized detection lane in a handheld, portable assay and sensor system; maintaining the functionalized detection lane of the SAW sensor dry until the sample is fluidicly disposed in the detection lane; fluidicly disposing the sample in the functionalized detection lane; removing fluid the functionalized detection lane to concentrate the sample in the functionalized detection lane to increase the probability of a specific antibody-antigen interaction; washing the functionalized detection lane so that substantially only the specific antigen-antibody interaction remains in the functionalized detection lane; removing fluid from the functionalized detection lane again; and measuring concentration of the sample while the functionalized detection lane is fluid-free.

Abstract: A solution for treating a fluid, such as water, is provided. An ultraviolet transparency of a fluid can be determined before or as the fluid enters a disinfection chamber. In the disinfection chamber, the fluid can be irradiated by ultraviolet radiation to harm microorganisms that may be present in the fluid. One or more attributes of the disinfection chamber, fluid flow, and/or ultraviolet radiation can be adjusted based on the transparency to provide more efficient irradiation and/or higher disinfection rates. In addition, various attributes of the disinfection chamber, such as the position of the inlet(s) and outlet(s), the shape of the disinfection chamber, and other attributes of the disinfection chamber can be utilized to create a turbulent flow of the fluid within the disinfection chamber to promote mixing and improve uniform ultraviolet exposure.

Abstract: A thermal infrared sensor array in a wafer-level package includes at least one infrared-sensitive pixel produced using silicon micro mechanics, comprising a heat-isolating cavity in a silicon substrate surrounded by a silicon edge, and a thin membrane connected to the silicone edge by of thin beams. The cavity extends through the silicon substrate to the membrane, and there are slots between the membrane, the beams and the silicon edge. A plurality of infrared-sensitive individual pixels are arranged in lines or arrays and are designed in a CMOS stack in a dielectric layer, forming the membrane, and are arranged between at least one cover wafer which is designed in the form of a cap and has a cavity and a base wafer. The cover wafer, the silicon substrate and the base wafer are connected to one another in a vacuum-tight manner and enclosing a gas vacuum.

Abstract: There is disclosed a transdermal analyte sensor device. The device includes a sensor cartridge having a membrane permeable to a target analyte transdermally received from a subject, a reservoir containing a fluid to receive the target analyte through the membrane and an enzyme to react with the target analyte to form a byproduct, a working electrode to generate an electrical current based on a concentration of a byproduct, and a cartridge electrical contact to transmit the electrical current. The device also includes a device body having a device electrical contact to receive the electrical current from the cartridge electrical contact, a transmitter to transmit a signal based on the electrical current to a monitoring device, and a cartridge receptacle to receive the sensor cartridge and position the membrane to contact skin of the subject.