Abstract: The present invention relates to electrophoresis. More particularly, the present invention relates to utilization of electrophoresis with controlled cooling. Still more particularly, the invention relates to a method and apparatus for separating chemical components in a solution in both a batch and a continuous mode.
Abstract: The present invention involves a dual column chromatographic apparatus with column switching capability that is useful in any pressurized fluid chromatography system. The apparatus has at least a first and second chromatographic column, a detector, a fluid conveyance system having a multivalve arrangement, pressurizable fluid conduit assembly, and a controller.The columns are adapted for containing stationary phase or packing for separation of a multicomponent sample into one or more components. The multi-valve arrangement has a plurality of multi-port, multi-modal valves and can include an ingress-egress valve; a guard pre-column valve; detector isolation valve; a set of four, four-port, multi-modal valves; or a set of two four-port, multi-modal valves and one six-port, multi-modal valve or a first valve set and a second valve set. The two chromatographic columns, multi-valve arrangement, and detector are linked for pressurized fluid communication by the pressurized fluid conduit assembly.
Type:
Grant
Filed:
March 23, 1990
Date of Patent:
December 10, 1991
Assignee:
Separations Technology, Inc.
Inventors:
Frederick D. Cazer, Barry L. Scott, Garth E. Strobel
Abstract: A method and apparatus for conducting electrophoretic separations is described in which heat exchange fluid is passed through hollow fibers in the electrophoretic chamber during the separation process and the separations are conducted in the interstices of the hollow fiber. Hollow fibers made of organic polymers, inorganic materials such as glass and silica, and natural fibers may be used.
Abstract: This invention relates to a column for use in preparative HPLC so structured as to insure a reproducible packing bed uniformity regardless of the particle size of the medium used.