Abstract: A method of titration using a combination continuous flow and pulse flow portable oxygen concentration system (system) with a patient includes: a) providing the system in a continuous flow mode and titrating the patient to a predetermined blood oxygen saturation using the system at one or more predetermined conditions in the continuous flow mode; b) providing the system in a pulse flow mode and titrating the patient to the same predetermined blood oxygen saturation as step a using the system at the same one or more predetermined conditions as in step a in the pulse flow mode; c) determining an Individualized Pulse Dose Equivalent (IPDE) correlation based on data obtained from steps a and b; d) providing the system with the IPDE correlation; and e) using the IPDE correlation to operate the concentrator in a more efficient manner.

Abstract: A compressor vibration isolation mount for isolating the vibrations of a compressor from the rest of a structure includes at least one frame; and at least one gimbal coupling the compressor to the at least one frame for partial rotation about at least one primary axis of rotation.

Abstract: Disclosed are devices, systems, and methods, including an oxygen delivery device that includes an oxygen delivery module to produce at least concentrated oxygen, a gas moving device to deliver air to the oxygen delivery module, at least one motor to controllably drive the gas moving device, an energy source to power at least the at least one motor, a pressure sensor to determine a pressure level, and a purity sensor to determine oxygen purity value. The device also includes a controller to control, based on the oxygen purity value and the pressure level, at least the gas moving device's operations and the oxygen delivery module's operations to cause the pressure resulting from gas moving device to be substantially at a pre-determined pressure value and to cause the purity level of the oxygen produced by the oxygen delivery module to be substantially at a pre-determined purity value.

Abstract: Disclosed are devices, systems, and methods, including an oxygen delivery device that includes an oxygen delivery module, at least one sensor to detect patient breathing, and a controller configured to control the oxygen delivery module to cause the oxygen delivery module to deliver oxygen to the patient based on data from the at least one sensor such that in response to a determination, based on data from the at least one sensor, that no breathing is detected for a first pre-determined period of time, the controller causes the oxygen delivery module to deliver oxygen to the patient in continuous flow mode, and in response to a determination, based on additional data from the at least one sensor, that breathing is detected for a second period of time, the controller causes the oxygen delivery module to deliver oxygen to the patient in a pulse flow mode.

Abstract: Disclosed are devices, systems, and methods, including an oxygen delivery device that includes an oxygen delivery module to produce at least concentrated oxygen, and a gas moving device to deliver air to the oxygen delivery module. The gas moving device includes at least one piston rotatable inside a first chamber defined in a housing, the rotational movement of the at least one piston inside the first chamber resulting in varying pressure generated in a first portion of the first chamber, and a vane member rigidly coupled to the at least one piston, the vane member being configured to move inside a vane chamber defined in the housing, the piston and the vane rigidly coupled to the piston define the first portion of the first chamber and a second portion of the first chamber.

Abstract: Disclosed are devices, systems, and methods, including an oxygen delivery device that includes an oxygen delivery module configured to deliver a pulse including greater than 100 mL of concentrated oxygen, and a controller configured to control the oxygen delivery module to cause the oxygen delivery module to deliver the pulse including greater than the 100 mL of the concentrated oxygen within approximately first 60% of a patient's inspiratory period. Also disclosed is a device that includes an oxygen delivery module, a piezoelectric valve coupled to an output of the oxygen delivery module to receive the concentrated oxygen, a driver to electrically actuate the piezoelectric valve, and a controller to control the driver to cause controllable actuation of the piezoelectric valve by the driver to cause controllable opening of the valve to enable oxygen flow to be directed for inhalation by a patient via the piezoelectric valve.

Abstract: A method of controlling bolus delivery in a pulse flow oxygen concentration system for a patient includes providing a pulse flow oxygen concentration system that delivers concentrated oxygen gas to the patient in boluses having a pulse bolus duration, the pulse flow oxygen concentration system including an open control for controlling the pulse bolus duration of the boluses; determining one or more respiratory conditions of the patient; and adjusting the open control to adjust the pulse bolus duration of the boluses in accordance with the determined one or more respiratory conditions of the patient.

Abstract: A gas separation device for separating oxygen gas from air includes a compressor; a concentrator; a measurement mechanism; and a flow control mechanism that includes a valve assembly for providing fluid flow control, the valve assembly having a motor; a valve body; and a plunger within the valve body and reciprocally driven by the motor, wherein the valve body including a fluid inlet, a fluid outlet, and a flow chamber therebetween, the flow chamber including a flow chamber wall and a flow chamber outlet, the plunger including a flexible member reciprocating within the flow chamber outlet to provide variable flow control therethrough, the flexible member including a lip seal engageable with the flow chamber wall during reciprocation of the plunger and flexible member to provide a seal therebetween.

Abstract: A needle valve assembly for providing fluid flow control includes a motor; an internally threaded valve body; and an externally threaded plunger threadably engaged with the internally threaded valve body and rotatably and reciprocally driven by the motor, wherein the valve body including a fluid inlet, a fluid outlet, and a flow chamber therebetween, the flow chamber including a flow chamber wall and a flow chamber outlet, the plunger including a flexible needle member reciprocating within the flow chamber outlet to provide variable flow control therethrough, the flexible needle member including a lip seal engageable with the flow chamber wall during reciprocation of the plunger and flexible needle member to provide a seal therebetween.

Abstract: The present invention relates to a rotary valve assembly for a pressure swing adsorption system. The rotary valve assembly includes a first valve member and a second valve member relatively rotatable about a common center of rotation to provide valving action for selectively transferring fluids therethrough. The second valve member has a first fluid section with at least one aperture adapted for transferring a first fluid of a first pressure and composition therethrough and a second fluid section with at least one aperture adapted for transferring a second fluid of a second pressure and composition therethrough. The first valve member has a first fluid section with at least one passage for transferring the first fluid in the valve assembly and a second fluid section with at least one passage for transferring the second fluid in the valve assembly.

Abstract: The present invention is directed to a much safer and less expensive way of providing portable oxygen from a gas concentrator for patients who do not want to be tied to a stationary machine or restricted by present oxygen technology. The present invention involves a home liquid oxygen ambulatory system for supplying a portable supply of oxygen, where a portion of the gaseous oxygen output obtained from an oxygen concentrator is condensed into liquid oxygen. The system includes an oxygen concentrator which separates oxygen gas from the ambient air, a condenser in communication with the oxygen concentrator for receiving and liquefying the oxygen gas flow, a cryocooler associated with the condenser, and a first storage dewar in fluid communication with the condenser and adapted to store the oxygen liquefied by the condenser, the first storage dewar including means for transferring liquid oxygen from the first dewar to a second dewar for storing a quantity of oxygen suitable for moveable oxygen treatment.

Abstract: A portable oxygen concentrator system adapted to be readily transported by a user includes a rechargeable energy source and a concentrator powered by the energy source. The concentrator converts ambient air into concentrated oxygen gas for the user and includes a plurality of adsorption beds and a rotary valve assembly. The rotary valve assembly is relatively rotatable with respect to the plurality of adsorption beds to provide valving action for selectively transferring fluids through the plurality of adsorption beds for converting ambient air into concentrated oxygen gas for the user. The ratio of adiabatic power to oxygen flow for the concentrator is in the range of 6.2 W/LPM to 23.0 W/LPM.

Abstract: A control system for a home ambulatory liquid oxygen system having an oxygen concentrator, condenser, cryocooler, a heater and a storage dewar, includes an oxygen concentration sensor which senses the concentration of oxygen gas generated by the oxygen concentrator and generates a first signal in response thereto; a liquid level sensor which senses the liquid level in the dewar and generates a second signal in response thereto; a temperature sensor which senses the temperature in the dewar and generates a third signal in response thereto; and a microprocessor for receiving the first, second and third signals for computing the flow concentration of gaseous oxygen out of the concentrator and into the condenser, the level of liquid oxygen in the dewar, the temperature in the dewar and for controlling the transfer of liquid oxygen from the storage dewar.

Abstract: The present invention is directed to a portable oxygen concentrator system adapted to be transported by a user. The portable oxygen concentrator system includes an energy source, an air separation device powered by the energy source and adapted to convert ambient air into concentrated oxygen gas for the user, at least one sensor adapted to sense one or more conditions indicative of the oxygen gas needs of the user, and a control unit interrelated with the air separation device and the at least one sensor to control the air separation device so as to supply an amount of oxygen gas equivalent to the oxygen gas needs of the user based at least in part upon the one or more conditions sensed by the at least one sensor.

Abstract: The present invention is directed to a much safer and less expensive way of providing portable oxygen from a gas concentrator for patients who do not want to be tied to a stationary machine or restricted by present oxygen technology. In one preferred embodiment, the present invention splits off some of the excess capacity gas flow from a gas concentrator which is then stored via liquefaction. The stored gas can then be used as a portable supply. A portion of the oxygen gas flow generated by the oxygen concentrator is channeled to a condenser which receives and liquefies the oxygen gas using cryocooler. A storage dewar is used for storing the oxygen liquefied by the condenser. Liquid is then selectively transferred to a smaller portable dewar. A controller can be used for monitoring the parameters of liquefaction, including oxygen concentration, the amount of liquid oxygen in the dewar, and for controlling the parameters of liquid oxygen generation and transfer.

Abstract: The present invention is directed to a portable oxygen concentrator system adapted to be transported by a user. The portable oxygen concentrator system includes an energy source, an air separation device powered by the energy source and adapted to convert ambient air into concentrated oxygen gas for the user, at least one sensor adapted to sense one or more conditions indicative of the oxygen gas needs of the user, and a control unit interrelated with the air separation device and the at least one sensor to control the air separation device so as to supply an amount of oxygen gas equivalent to the oxygen gas needs of the user based at least in part upon the one or more conditions sensed by the at least one sensor.

Abstract: A portable oxygen concentrator system adapted to be readily transported by a user includes a rechargeable energy source and a concentrator powered by the energy source. The concentrator converts ambient air into concentrated oxygen gas for the user and includes a plurality of adsorption beds and a rotary valve assembly. The rotary valve assembly is relatively rotatable with respect to the plurality of adsorption beds to provide valving action for selectively transferring fluids through the plurality of adsorption beds for converting ambient air into concentrated oxygen gas for the user. The ratio of adiabatic power to oxygen flow for the concentrator is in the range of 6.2 W/LPM to 23.0 W/LPM.

Abstract: The present invention involves a vacuum-pressure swing adsorption process for the separation of components of a fluid mixture. The process includes (a) transferring a fluid mixture through an adsorbent bed at an elevated pressure Ph so as to produce a purified product fluid; (b) venting the adsorbent bed down to an ambient fluid pressure Pa; (c) applying a vacuum force to the adsorbent bed to bring the adsorbent bed to a reduced pressure Pl; and (d) venting the adsorbent bed up to an ambient fluid pressure Pa.

Abstract: The present invention relates to a rotary valve assembly for a pressure swing adsorption system. The rotary valve assembly includes a first valve member and a second valve member relatively rotatable about a common center of rotation to provide valving action for selectively transferring fluids therethrough. The second valve member has a first fluid section with at least one aperture adapted for transferring a first fluid of a first pressure and composition therethrough and a second fluid section with at least one aperture adapted for transferring a second fluid of a second pressure and composition therethrough. The first valve member has a first fluid section with at least one passage for transferring the first fluid in the valve assembly and a second fluid section with at least one passage for transferring the second fluid in the valve assembly.

Abstract: The present invention relates to a rotary valve assembly for a pressure swing adsorption system. The rotary valve assembly includes a first valve member and a second valve member relatively rotatable about a common center of rotation to provide valving action for selectively transferring fluids therethrough. The second valve member has a first fluid section with at least one aperture adapted for transferring a first fluid of a first pressure and composition therethrough and a second fluid section with at least one aperture adapted for transferring a second fluid of a second pressure and composition therethrough. The first valve member has a first fluid section with at least one passage for transferring the first fluid in the valve assembly and a second fluid section with at least one passage for transferring the second fluid in the valve assembly.