Abstract: Provided herein are methods of determining NAT acetylation status of a subject with a 3,4-DAP-sensitive disease, methods of selecting a dose of 3,4-DAP or a pharmaceutically acceptable salt thereof adjusted to a subject's acetylation status, methods of administering 3,4-diaminopyridine or a pharmaceutically acceptable salt thereof to a patient in need thereof, and methods of treating 3,4-DAP sensitive diseases.
Type:
Grant
Filed:
May 23, 2023
Date of Patent:
January 16, 2024
Assignee:
SERB SA
Inventors:
Marvin R. Garovoy, Peter E. Haroldsen, Donald G. Musson
Abstract: Provided herein are methods of determining NAT acetylation status of a subject with a 3,4-DAP-sensitive disease, methods of selecting a dose of 3,4-DAP or a pharmaceutically acceptable salt thereof adjusted to a subject's acetylation status, methods of administering 3,4-diaminopyridine or a pharmaceutically acceptable salt thereof to a patient in need thereof, and methods of treating 3,4-DAP sensitive diseases.
Type:
Grant
Filed:
May 23, 2023
Date of Patent:
December 19, 2023
Assignee:
SERB SA
Inventors:
Marvin R. Garovoy, Peter E. Haroldsen, Donald G. Musson
Abstract: Provided herein are methods of determining NAT acetylation status of a subject with a 3,4-DAP-sensitive disease, methods of selecting a dose of 3,4-DAP or a pharmaceutically acceptable salt thereof adjusted to a subject's acetylation status, methods of administering 3,4-diaminopyridine or a pharmaceutically acceptable salt thereof to a patient in need thereof, and methods of treating 3,4-DAP sensitive diseases.
Type:
Grant
Filed:
October 15, 2021
Date of Patent:
March 15, 2022
Assignee:
SERB SA
Inventors:
Marvin R. Garovoy, Peter E. Haroldsen, Donald G. Musson
Abstract: Provided herein are methods of determining NAT acetylation status of a subject with a 3,4-DAP-sensitive disease, methods of selecting a dose of 3,4-DAP or a pharmaceutically acceptable salt thereof adjusted to a subject's acetylation status, methods of administering 3,4-diaminopyridine or a pharmaceutically acceptable salt thereof to a patient in need thereof, and methods of treating 3,4-DAP sensitive diseases.
Type:
Grant
Filed:
October 15, 2021
Date of Patent:
March 15, 2022
Assignee:
SERB SA
Inventors:
Marvin R. Garovoy, Peter E. Haroldsen, Donald G. Musson
Abstract: Provided herein are methods of determining NAT acetylation status of a subject with a 3,4-DAP-sensitive disease, methods of selecting a dose of 3,4-DAP or a pharmaceutically acceptable salt thereof adjusted to a subject's acetylation status, methods of administering 3,4-diaminopyridine or a pharmaceutically acceptable salt thereof to a patient in need thereof, and methods of treating 3,4-DAP sensitive diseases.
Type:
Grant
Filed:
October 15, 2021
Date of Patent:
March 8, 2022
Assignee:
SERB SA
Inventors:
Marvin R. Garovoy, Peter E. Haroldsen, Donald G. Musson
Abstract: Provided herein are methods of determining NAT acetylation status of a subject with a 3,4-DAP-sensitive disease, methods of selecting a dose of 3,4-DAP or a pharmaceutically acceptable salt thereof adjusted to a subject's acetylation status, methods of administering 3,4-diaminopyridine or a pharmaceutically acceptable salt thereof to a patient in need thereof, and methods of treating 3,4-DAP sensitive diseases.
Type:
Grant
Filed:
September 1, 2020
Date of Patent:
July 13, 2021
Assignee:
SERB SA
Inventors:
Marvin R. Garovoy, Peter E. Haroldsen, Donald G. Musson
Abstract: Provided herein are methods of determining NAT acetylation status of a subject with a 3,4-DAP-sensitive disease, methods of selecting a dose of 3,4-DAP or a pharmaceutically acceptable salt thereof adjusted to a subject's acetylation status, methods of administering 3,4-diaminopyridine or a pharmaceutically acceptable salt thereof to a patient in need thereof, and methods of treating 3,4-DAP sensitive diseases.
Type:
Grant
Filed:
June 29, 2012
Date of Patent:
October 6, 2020
Assignee:
SERB SA
Inventors:
Marvin R. Garovoy, Peter E. Haroldsen, Donald G. Musson