Abstract: Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.
Type:
Application
Filed:
April 5, 2021
Publication date:
August 12, 2021
Applicant:
Seres Therapeutics, Inc,
Inventors:
Gregory MCKENZIE, Mary-Jane LOMBARDO MCKENZIE, David N. COOK, Marin VULIC, Geoffrey VON MALTZAHN, Brian GOODMAN, John Grant AUNINS, Matthew R. HENN, David Arthur BERRY, Jonathan WINKLER
Abstract: Our client, Seres Therapeutics, has asked us to file a new provisional application related to bacterial compositions and the use of such compositions for the treatment of inflammatory bowel disease.
Type:
Application
Filed:
May 24, 2019
Publication date:
July 1, 2021
Applicant:
Seres Therapeutics, Inc.
Inventors:
Asuncion MARTINEZ, Edward J. O'BRIEN, Sheri Lynn SIMMONS, David COOK, Matthew R. HENN, Christopher B. FORD, Divya BALASUBRAMANIAN, Ambar PIÑA, Liyang DIAO, Meghan CHAFEE, Marin VULIC, Madhumitha NANDAKUMAR, Sumon DATTA, Latta JAYARAMAN
Abstract: Provided are therapeutic compositions containing Ecobiotic™ populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
Type:
Application
Filed:
December 14, 2020
Publication date:
June 10, 2021
Applicant:
Seres Therapeutics, Inc,
Inventors:
Matthew R. HENN, Geoffrey von MALTZAHN, Anthony Mario D'ONOFRIO, Kevin Daniel LITCOFSKY, David Arthur BERRY, David N. COOK, Noubar B. AFEYAN, John Grant AUNINS
Abstract: Provided are therapeutic compositions containing Ecobiotic™ populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
Type:
Application
Filed:
December 14, 2020
Publication date:
June 10, 2021
Applicant:
Seres Therapeutics, Inc,
Inventors:
Matthew R. HENN, Geoffrey von MALTZAHN, Anthony Mario D'ONOFRIO, Kevin Daniel LITCOFSKY, David Arthur BERRY, David N. COOK, Noubar B. AFEYAN, John Grant AUNINS
Abstract: Provided are therapeutic compositions containing Ecobiotic™ populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
Type:
Application
Filed:
December 14, 2020
Publication date:
June 10, 2021
Applicant:
Seres Therapeutics, Inc,
Inventors:
Matthew R. HENN, Geoffrey von MALTZAHN, Anthony Mario D'ONOFRIO, Kevin Daniel LITCOFSKY, David Arthur BERRY, David N. COOK, Noubar B. AFEYAN, John Grant AUNINS
Abstract: Provided are therapeutic compositions containing Ecobiotic™ populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
Type:
Application
Filed:
December 14, 2020
Publication date:
June 10, 2021
Applicant:
Seres Therapeutics, Inc,
Inventors:
Matthew R. HENN, Geoffrey von MALTZAHN, Anthony Mario D'ONOFRIO, Kevin Daniel LITCOFSKY, David Arthur BERRY, David N. COOK, Noubar B. AFEYAN, John Grant AUNINS
Abstract: Provided herein are bacterial compositions that are useful for treating and preventing complications and side effects associated with an inflammatory bowel disease.
Type:
Application
Filed:
March 29, 2019
Publication date:
April 29, 2021
Applicant:
Seres Therapeutics, Inc.
Inventors:
Madhumitha NANDAKUMAR, Edward J. O'BRIEN, Sumon DATTA
Abstract: Provided are defined bacterial compositions for the maintenance or restoration of a healthy microbiota in the gastrointestinal tract of a mammalian subject, and methods for populating the gastrointestinal tract of a subject. Provided also are bacterial formulations for oral or gastric administration to a mammalian subject in an effective amount for prevention or treatment of a gastrointestinal disease, disorder or condition.
Type:
Grant
Filed:
February 4, 2014
Date of Patent:
April 13, 2021
Assignee:
Seres Therapeutics, Inc.
Inventors:
Noubar B. Afeyan, Mary-Jane Lombardo McKenzie, Kevin Daniel Litcofsky, David N. Cook, Matthew R. Henn, Geoffrey von Maltzahn
Abstract: Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.
Type:
Grant
Filed:
August 3, 2018
Date of Patent:
April 6, 2021
Assignee:
Seres Therapeutics, Inc.
Inventors:
Gregory McKenzie, Mary-Jane Lombardo McKenzie, David N. Cook, Marin Vulic, Geoffrey von Maltzahn, Brian Goodman, John Grant Aunins, Matthew R. Henn, David Arthur Berry, Jonathan Winkler
Abstract: Provided are therapeutic compositions containing combinations of bacteria, for the maintenance or restoration of a healthy microbiota in the gastrointestinal tract of a mammalian subject, and methods for use thereof.
Type:
Grant
Filed:
May 25, 2018
Date of Patent:
January 5, 2021
Assignee:
Seres Therapeutics, Inc.
Inventors:
Matthew R. Henn, David N. Cook, Toshiro K. Ohsumi, Mary-Jane Lombardo McKenzie, Kevin D. Litcofsky, Han Zhang, John Grant Aunins, David Arthur Berry
Abstract: Provided are therapeutic compositions containing Ecobiotic™ populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
Type:
Grant
Filed:
December 17, 2018
Date of Patent:
December 15, 2020
Assignee:
Seres Therapeutics, Inc.
Inventors:
Matthew R. Henn, Geoffrey von Maltzahn, Anthony Mario D'Onofrio, Kevin Daniel Litcofsky, David Arthur Berry, David N. Cook, Noubar B. Afeyan, John Grant Aunins
Abstract: Provided are therapeutic compositions containing microbial populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
Type:
Application
Filed:
December 21, 2018
Publication date:
November 5, 2020
Applicant:
SERES THERAPEUTICS, INC.
Inventors:
Matthew R. Henn, Kevin Daniel Litcofsky, Anthony Mario D'Onofrio, Toshiro K. Ohsumi, Mary-Jane Lombardo McKenzie, Geoffrey von Maltzahn, David N. Cook, David Arthur Berry, Noubar B. Afeyan, John Grant Aunins
Abstract: Provided are therapeutic compositions containing Ecobiotic™ populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
Type:
Application
Filed:
December 17, 2018
Publication date:
November 21, 2019
Applicant:
Seres Therapeutics, Inc.
Inventors:
Matthew R. Henn, Geoffrey von Maltzahn, Anthony Mario D'Onofrio, Kevin Daniel Litcofsky, David Arthur Berry, David N. Cook, Noubar B. Afeyan, John Grant Aunins
Abstract: Provided are therapeutic compositions containing microbial populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
Type:
Grant
Filed:
November 25, 2014
Date of Patent:
April 16, 2019
Assignee:
Seres Therapeutics, Inc.
Inventors:
Matthew R. Henn, Kevin Daniel Litcofsky, Anthony Mario D'Onofrio, Toshiro K. Ohsumi, Mary-Jane Lombardo McKenzie, Geoffrey von Maltzahn, David N. Cook, David Arthur Berry, Noubar B. Afeyan, John Grant Aunins
Abstract: Provided are therapeutic compositions containing combinations of bacteria, for the maintenance or restoration of a healthy microbiota in the gastrointestinal tract of a mammalian subject, and methods for use thereof.
Type:
Grant
Filed:
March 17, 2014
Date of Patent:
September 18, 2018
Assignee:
Seres Therapeutics, Inc.
Inventors:
Matthew R. Henn, David N. Cook, Toshiro K. Ohsumi, Mary-Jane Lombardo McKenzie, Kevin D. Litcofsky, Han Zhang, John Grant Aunins, David Berry
Abstract: Methods and compositions for populating the gastrointestinal tract of a subject are described. Methods include administering to a subject a therapeutic composition comprising a purified population of spore-forming bacteria produced by providing a fecal material and subjecting the material to a treatment step resulting in purification of spore-forming bacteria. Methods include administering an amount effective to engraft and/or augment in the gastrointestinal tract in order to treat or prevent a dysbiosis in the mammalian subject.
Type:
Grant
Filed:
February 4, 2014
Date of Patent:
September 4, 2018
Assignee:
Seres Therapeutics, Inc.
Inventors:
Geoffrey Von Maltzahn, Matthew R. Henn, David N. Cook, David Arthur Berry, Noubar B. Afeyan, Brian Goodman, Mary-Jane Lombardo McKenzie, Marin Vulic
Abstract: Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.
Type:
Grant
Filed:
December 19, 2017
Date of Patent:
September 4, 2018
Assignee:
Seres Therapeutics, Inc.
Inventors:
Gregory McKenzie, Mary-Jane Lombardo McKenzie, David N. Cook, Marin Vulic, Geoffrey von Maltzahn, Brian Goodman, John Grant Aunins, Matthew R. Henn, David Arthur Berry, Jonathan Winkler