Patents Assigned to SERGAS
  • Agent for capturing tumor cells and methods of use thereof
    Patent number: 10111935
    Abstract: The present invention relates to a composition for modulating tumor cell dissemination, in particular metastatic cancer cells. In particular, the invention relates to an agent for modulating metastatic tumor cell dissemination for use in the treatment and/or prevention of a metastatic cancer wherein the agent comprises an extracellular matrix (ECM) protein carried on a polycarbonate polyurethane matrix, and wherein the agent binds to tumor cells when implanted in a body. The invention also relates to a product, comprising an agent for modulating metastatic tumor cell dissemination, and to a method of treatment or prevention of cancer.
    Type: Grant
    Filed: April 30, 2015
    Date of Patent: October 30, 2018
    Assignees: FUNDACIÖN PEDRO BARRIÉ DE LA MAZA, CONDO DE FENOSA, SERGAS, UNIVERSITY OF SANTIAGO DE COMPOSTELA, FUNDACION RAMÓN DOMINGUEZ, BIOMERIX CORPORATION
    Inventors: Alexandre De La Fuente Gonzalez, Rafael Lopez, Miguel Abal Posada, Lawrence Patrick Lavelle, Jr.
  • Methods of capturing tumor cells
    Patent number: 10022400
    Abstract: The present invention relates to a composition for modulating tumor cell dissemination, in particular metastatic cancer cells. In particular, the invention relates to an agent for modulating metastatic tumor cell dissemination for use in the treatment and/or prevention of a metastatic cancer wherein the agent is a capture agent and/or a chemoattractant for tumor cells. The invention also relates to a product, comprising an agent for modulating metastatic tumor cell dissemination, and to a method of treatment or prevention of cancer.
    Type: Grant
    Filed: November 26, 2013
    Date of Patent: July 17, 2018
    Assignees: Fundacion Ramon Dominguez, SERGAS
    Inventors: Alexandre de la Fuente Gonzalez, Rafael Lopez, Miguel Abal Posada
  • AGENT, PRODUCT AND USE
    Publication number: 20170246258
    Abstract: The present invention relates to a composition for modulating tumor cell dissemination, in particular metastatic cancer cells. In particular, the invention relates to an agent for modulating metastatic tumor cell dissemination for use in the treatment and/or prevention of a metastatic cancer wherein the agent an extracellular matrix (ECM) protein carried on a polycarbonate polyurethane matrix. The invention also relates to a product, comprising an agent for modulating metastatic tumor cell dissemination, and to a method of treatment or prevention of cancer.
    Type: Application
    Filed: April 30, 2015
    Publication date: August 31, 2017
    Applicants: FUNDACIÓN PEDRO BARRIÉ DE LA MAZA, CONDE DE FENOSA, SERGAS, UNIVERSITY OF SANTIAGO DE COMPOSTELA, FUNDACION RAMÓN DOMINGUEZ, BIOMERIX CORPORATION
    Inventors: Alexandre DE LA FUENTE GONZALEZ, Rafael LOPEZ, Miguel Abal POSADA, Lawrence Patrick LAVELLE, Jr.
  • AGENT, PRODUCT AND USE
    Publication number: 20170049860
    Abstract: The present invention relates to a composition for modulating tumor cell dissemination, in particular metastatic cancer cells. In particular, the invention relates to an agent for modulating metastatic tumor cell dissemination for use in the treatment and/or prevention of a metastatic cancer wherein the agent an extracellular matrix (ECM) protein carried on a polycarbonate polyurethane matrix. The invention also relates to a product, comprising an agent for modulating metastatic tumor cell dissemination, and to a method of treatment or prevention of cancer.
    Type: Application
    Filed: April 30, 2015
    Publication date: February 23, 2017
    Applicants: Fundacion Pedro Barrie De La Maza,Conde De Fenosa, Sergas, University of Santiago De Compostela, Fundacion Ramon Dominguez, Biomerix Corporation
    Inventors: Alexandre DE LA FUENTE GONZALEZ, Rafael LOPEZ, Miguel Abal POSADA, Lawrence Patrick LAVELLE, JR.
  • MOLECULAR BLOCK-MATCHING METHOD FOR GEL IMAGE ANALYSIS
    Publication number: 20130108140
    Abstract: A method for analysis of 2-D gel images obtained using electrophoresis. More particularly, a molecular block-matching method for establishing the correspondence between protein spots in a diagnostic-test image and protein spots in a reference image. Individual protein spot matching is performed, thereby removing the need for alignment of the entire reference and test images and permitting automatic labeling of individual protein spots. The method for analysis of 2-D gel images is fully automated, thus making it ideally suited for protein information retrieval systems.
    Type: Application
    Filed: April 24, 2012
    Publication date: May 2, 2013
    Applicants: UNIVERSIDADE DE A CORUNA, FUNDACION CHUAC, SERGAS
    Inventors: Alejandro Celestino Pazos Sierra, Julián Alfonso Dorado de la Calle, Francisco Blanco García, Javier Pereira Loureiro, Juan Ramón Rabuñal Dopico, Cristina Ruiz Romero, Jose Antonio Seoane Fernández, Ana Maria Freire Veiga, Enrique Fernández Blanco, Alvaro Rodriguez Tajes, Carlos Fernandez Lozano, Ana Belén Porto Pazos, Cristian Robert Munteanu