Patents Assigned to Serono Laboratories, Inc.
  • Patent number: 5219729
    Abstract: A new diagnostic assay of sperm function has been found for infertility treatment and monitoring programs. The hemizona assay (HZA) measures tight binding of human spermatozoa to the human hemizona pellucida.
    Type: Grant
    Filed: February 25, 1988
    Date of Patent: June 15, 1993
    Assignee: Serono Laboratories, Inc.
    Inventor: Gary D. Hodgen
  • Patent number: 4845077
    Abstract: A method of inducing ovulation by administering exogenous human menopausal gonadotropins employs FSH as the exogenous human menopausal gonadotripin in the absence of exogenous LH, preferably in conjunction with a gonadotropin releasing factor antagonists. One particular application of the method is in vitro fertilization.
    Type: Grant
    Filed: July 9, 1987
    Date of Patent: July 4, 1989
    Assignee: Serono Laboratories, Inc.
    Inventor: Gary D. Hodgen
  • Patent number: 4725579
    Abstract: A method for the treatment of infertility is described involving recruitment of more than one oocyte by a unique and hitherto undescribed combination of goandotropins, the harvest of these oocytes prior to their spontaneous ovulation and their fertilization by exposure to sperm in vitro so that the resulting concepti can be transferred to the uteri of the donors and so overcome several forms of infertility.
    Type: Grant
    Filed: February 21, 1985
    Date of Patent: February 16, 1988
    Assignee: Serono Laboratories, Inc.
    Inventors: Howard W. Jones, Jr., Georgeanna S. Jones
  • Patent number: 4589402
    Abstract: A method of in vitro fertilization therapy, which includes means for inducing ovulation by administering an exogenous human menopausal gonadotropin preparation and human chorionic gonadotropin, harvesting the mature follicles, combining the ovum with spermatazoa in vitro and transferring the conceptus into the uterus is improved by employing FSH as the exogenous human menopausal gonadotropin in the absence of exogenous LH.
    Type: Grant
    Filed: July 26, 1984
    Date of Patent: May 20, 1986
    Assignee: SErono Laboratories, Inc.
    Inventors: Gary D. Hodgen, Howard W. Jones, Jr., Georgeanna S. Jones
  • Patent number: 4311688
    Abstract: Antibody to anti human chorionic gonadotropin and/or antibody to anti human chorionic gonadotropin-beta subunit labeled with technetium-99m, iodine-123, iodine-125 or iodine-131 are/is administered to a human after the human has been administered anti-hCG and/or anti-hCG beta. The biodistribution of the labeled composition accumulates at cancer sites, e.g. tumors that produce human chorionic gonadotropin (hCG), human chorionic gonadotripin-like material, and a compound similar to and/or identical to the beta-chain of chorionic gonadotropin, or mixtures thereof which would bind specifically to anti-hCG and/or anti-hCG-beta.
    Type: Grant
    Filed: October 29, 1979
    Date of Patent: January 19, 1982
    Assignees: Serono Laboratories Inc., University Patents Inc.
    Inventors: Scott W. Burchiel, David R. Crockford, Buck A. Rhodes
  • Patent number: 4267101
    Abstract: Human Relaxin is recovered from human fetal membranes, and preferably from the chorion-decidua membranes.
    Type: Grant
    Filed: February 1, 1980
    Date of Patent: May 12, 1981
    Assignee: Serono Laboratories Inc.
    Inventor: Mario Bigazzi
  • Patent number: 4062942
    Abstract: Partially desialylated human Chorionic Gonadotropin is used after menotropin administration to induce ovulation.
    Type: Grant
    Filed: February 17, 1976
    Date of Patent: December 13, 1977
    Assignee: Serono Laboratories, Inc.
    Inventor: Pietro Donini
  • Patent number: 4001228
    Abstract: This invention relates to certain 2-thiol-4,5-diphenyloxazole S-derivatives, to processes for their preparation and to therapeutic compositions containing them.
    Type: Grant
    Filed: July 23, 1975
    Date of Patent: January 4, 1977
    Assignee: Serono Laboratories, Inc.
    Inventor: Gabriele Mattalia