Abstract: In various aspects and embodiments, the invention provides a method of determining breast cancer status of a subject, the method comprising determining a methylation state for each of a plurality of cytosine-guanine dinucleotide (CpG) sites in a sample obtained from the subject, calculating a cancer presence differential methylation level and an invasiveness differential methylation level based on the methylation states of the plurality of CpG sites, and comparing the cancer presence differential methylation level and the invasiveness differential methylation level to a predetermined cancer status reference level and a predetermined invasiveness reference level, wherein when the cancer presence differential methylation level deviates from the predetermined cancer status reference level, the presence of breast cancer is indicated in the subject, and when the invasiveness differential methylation level deviates from the predetermined invasiveness reference level, the presence of invasive breast cancer is indica

Abstract: Existing approaches for item matching that are used for retail strategies are based on similarity matching, however, do not consider user mindset, magnitude present across quantitative AVs and segment specific customer interest on certain qualitative AVs. Embodiments of the present disclosure provide a method and system for Machine Learning (ML) based item matching by considering user mindset, magnitude present across quantitative AVs and segment specific customer interest on certain qualitative AV. The item matching approach disclosed, performs data analytics at the AV level to identify possible close matching items from the list of available partially matching as well as non-matching items. The method disclosed primarily performs Attribute (AT) enrichment by quantizing all the qualitative AVs to be analyzed. Weights are assigned to all the quantized AVs based on a Demand Transfer (DT) value provided by a Customer Decision Tree (CDT), wherein the CDT captures the user mindset.

Abstract: A connection includes a first expandable tubular member having a first screw threadform defined by a first plurality of crests, roots, and flanks, where each flank separates each crest from each root. The connection also includes a second expandable tubular member having a second screw threadform defined by a second plurality of crests, roots, and flanks, where each flank separates each crest from each root. The crests and roots are substantially axial to the tubular members and the flanks are substantially radial to the tubular members. The first expandable tubular member and the second expandable tubular member are configured to connect when the first threadform engages with the second threadform. Clearances are formed between the first plurality of flanks and the second plurality of flanks when the first and second expandable tubular members connect.

Abstract: Compliance with retail display regulations that retailers are subject to within a plurality of jurisdictions is managed. Retail display regulations may differ from jurisdiction to jurisdiction. To facilitate compliance, retail display regulations for a plurality of jurisdictions are centrally maintained. The regulations may then be used to dynamically generate retail display materials for locations across a plurality of jurisdictions with different regulatory schemes. The central storage and/or maintenance of the retail display regulations may facilitate compliance with disparate regulatory schemes that retailers are subject to based in part of retail location. Central storage of the retail display regulations may facilitate certification of compliance by regulating entities associated with the jurisdictions.

Abstract: Disclosed are examples of systems, methods and techniques related to delivering a service widget that collects data and provides a service. A service widget is provided in response to a widget delivery request received from a user browser. The delivered service widget enables the user browser to request item-related services from an enterprise. A request for the item-related services is received by an enterprise from the delivered service widget. Provision of the service is enabled upon confirmation that an authentication token fetched from the client backend system is valid for the client backend system, the services request may be delivered to an enterprise server. The enterprise, in response to an analysis of the information related to the item available for purchase, may indicate that the item available for purchase meets a purchase threshold of the enterprise and provide an evaluation result including parameters of the item-related services.

Abstract: A disadvantage of existing betting operations is the implementation of fixed odds and pari-mutuel betting on specific and dedicated systems. This results in higher acquisition and maintenance costs as compared with a single system. According to the present invention, a single system allows both fixed odds and pari-mutuel betting to be offered on a single system wherein the system effects a computer-implemented method of wagering, including: receiving, via a communications network, a wager from a customer in respect of a wagered event and a wagered product; storing the wager, in an electronic data store, and associating the wager with the wagered event, the wagered product and a customer account, wherein the computer system manages the electronic data store, having stored therein, a plurality of events, a plurality of products and a plurality of customers, all of which are independently defined.

Abstract: A sealing system connecting first and second tubular members includes a first curvilinear sealing surface on the first tubular member and a second curvilinear sealing surface on the second tubular member. Both the first and second curvilinear sealing surfaces are disposed between two sets of threading on the respective first and second tubular members. When the first and second tubular members are in a connected configuration, the first and second curvilinear sealing surfaces contact and interfere to form an annular curvilinear center seal. A relief pocket may be disposed adjacent to the first and/or second curvilinear sealing surfaces to contain excess lubricant between the first and second tubular members.

Abstract: One aspect of the present disclosure provides an imaging method including: specifying an imaging focus region on a subject to be imaged, applying radiofrequency pulses to the subject to interact with a magnetic field gradient, wherein the radiofrequency pulses successively bend magnetization phases of respective electromagnetic signals from the specified imaging focus region, resulting in magnified pixel data, and generating a magnified image of the imaging focus region based on the magnified pixel data.

Abstract: Aspects described herein may allow for the application of an artificial neural network architecture to identify intrusion in a database. Changes to components of a data table of the database may be tracked as a snapshot of the changes over a period of time. Any change in the data table may be associated with a user. Utilizing multiple snapshots, a background substitution technique may be utilized to generate a matrix of the changes to the data table over a period of time. A model having an artificial neural network architecture may utilize the matrix as an input set to identify the user as an unauthorized user accessing the database.

Abstract: A sleeve operable to at least partially contain two cylindrical articles in side-by-side or back-to-back relation, the sleeve including first and second openings or a single opening in a bottom thereof and the first and second cylindrical articles contained within the sleeve such that portions of the first and second cylindrical articles are exposed outside the sleeve.

Abstract: Ostomy tubes, particularly gastrostomy tubes, with improved retention means are provided. More specifically, retention structures, such as bolsters, for gastrostomy tubes are provided, configured to removably assemble to one end of a gastrostomy tube to facilitate replacement and removal of the tube. The retention structures provided herein may comprise one or more removably assembled retention elements. Further provided are gastrostomy tubes comprising such retention structures, and methods for percutaneous endoscopic gastrostomy utilizing same.

Abstract: A system for continuously circulating fluid in a wellbore includes a control system comprising a memory, a power source, and a user interface, along with a drill string subassembly having an inlet and an outlet, and defining a flow path from the inlet to the outlet. The conduit includes a lateral port to the flow path between the inlet and the outlet. The drill string subassembly also as a first valve that controls flow to the flow path from the lateral port and a second valve that controls flow to the flow path from the inlet. The drill string subassembly may also include a sensor that generates a fluid coupling signal responsive to a coupling between the lateral port and secondary fluid supply source, and includes a synchronous actuation member configured open the first valve and close the second valve in response to, for example, the fluid coupling signal.

Abstract: A system for verifying a user identity. The system comprises one or more memory devices storing instructions and one or more processors configured to execute the instructions. The processors are configured to receive information associated with an account of a user. The processors are further configured to generate a first profile, where the first profile being related to the user. The processors also receives an indication that the account is accessed by an accessor through an accessor device; and receive, from the accessor device, identity data comprising a plurality of data subsets associated with the accessor. The processors are configured to store the data subsets in respective clusters. The processors are further configured generate cluster analyses by analyzing the data subsets in respective clusters; and output the cluster analyses to node instances that weighs the cluster analyses outputs.

Abstract: Systems and methods are provided for determining whether an examination prompt elicits responses of a type for which the examination prompt is designed. Word types for each of a plurality of words in a plurality of responses to the examination prompt are identified. An evaluation distribution of the identified word types is determined. Predetermined distributions stored on a computer-readable medium associated with a plurality of different response types are accessed, and the evaluation distribution is compared to each of the predetermined distributions to determine which predetermined distribution the evaluation distribution is most similar. A determination is made as to whether the most similar distribution is associated with a same response type as the type for which the examination prompt is designed. An indication is made as to whether the examination prompt is deemed to elicit responses of the type for which the examination prompt is designed.

Abstract: A technique for engaged micro-interactions on digital devices is disclosed. In an embodiment, activities performed on a digital device are monitored. Further, at least one user accessing the digital device and friends associated with the user are determined based on the activities. Furthermore, a profile for the user and friends is created. Moreover, time spent and required to perform an action on content are determined based on the profile. In addition, a list of desires associated with the user and/or friends is determined based upon the activities and/or time spent and required to perform the action on the content. Also, the list of desires are ranked based on the activities to be performed by the user and friends. The user and/or friends are then engaged by providing a micro-interaction on the digital device based on the ranking of the list of desires and a time required to download online content.

Abstract: A distributed media outlet can include both a traffic and billing system, and a media delivery system that employ separate broadcast logs, or playlists. An enterprise hub can transmit broadcast instructions to the media outlet via an integrated services layer (ISL), which acts as a multidirectional gateway between the enterprise hub and the media outlet. The ISL can synchronize the separate playlists used by the traffic and billing system and the media delivery system by simultaneously injecting the broadcast instructions into both systems included in the media outlet. The media delivery system and traffic and billing system can continually re-synchronize their playlists by, at least in part, relaying information to one another via the integrated services layer.

Abstract: A system and method are disclosed that, in an embodiment, are related to goal-oriented generation of advertising spot sets. The system and method each involve: receiving spot inventory data associated with a plurality of TV stations; receiving a rule variable associated with an advertising rule; receiving a goal variable associated with a goal; applying the advertising rule to select a plurality of spots that are eligible to form one or more spot sets; forming or generating at least one of the spot sets depending, at least in part, on a proximity to the goal; and generating an output associated with the generated spot set.

Abstract: A device may receive location information that identifies a location of a user device associated with an individual. The location information may be received from the user device. The device may determine a distance between the location of the user device and each of a set of third party locations of a set of third parties using a digital map after receiving the location information. The device may provide a set of instructions to configure a user interface of an application associated with the user device to display messages of an electronic messaging account associated with the set of third parties after determining the distance between the location of the user device and each of the set of third party locations.

Abstract: Gene expression data provides a basis for more accurate identification and diagnosis of lymphoproliferative disorders. In addition, gene expression data can be used to develop more accurate predictors of survival. The present invention discloses methods for identifying, diagnosing, and predicting survival in a lymphoma or lymphoproliferative disorder on the basis of gene expression patterns. The invention discloses a novel microarray, the Lymph Dx microarray, for obtaining gene expression data from a lymphoma sample. The invention also discloses a variety of methods for utilizing lymphoma gene expression data to determine the identity of a particular lymphoma and to predict survival in a subject diagnosed with a particular lymphoma. This information will be useful in developing the therapeutic approach to be used with a particular subject.

Abstract: Disclosed herein are methods of detecting HIV-1 nucleic acids in a sample (such as from a sample containing or suspected to contain HIV-1 nucleic acid). In some examples, the methods include loop-mediated isothermal amplification (LAMP) or reverse transcription-LAMP (RT-LAMP). In some examples, the methods include contacting a sample with one or more sets of LAMP primers specific for HIV-1 (such as LAMP primers specific for an HIV-1 integrase nucleic acid or LAMP primers specific for an HIV-1 reverse transcriptase nucleic acid) under conditions sufficient to produce an amplification product and detecting the amplification product. Sets of LAMP primers for detection of HIV-1 integrase nucleic acids (such as SEQ ID NOs: 8-14 or 8-27) and HIV-1 reverse transcriptase nucleic acids (such as SEQ ID NOs: 1-7) are provided herein.