Abstract: Disclosed are methods of obtaining a cell population enriched for T cells with a phenotype, the method comprising: (a) obtaining a bulk population of T cells from a tumor sample of a patient; (b) specifically selecting T cells with a phenotype comprising markers CD3+, CD39?, and CD69? from the bulk population; and (c) separating the cells selected in (b) from cells which lack the phenotype to obtain a cell population enriched for T cells with the phenotype. Related methods of treating or preventing cancer, methods of selecting a therapy for a cancer patient, and methods for predicting the clinical response to immunotherapy in a cancer patient are also disclosed. Isolated or purified cell population obtained according to the methods and related pharmaceutical compositions are also disclosed.

Abstract: Systems, methods, and computer-readable media for communications between applications in a mobile operating system. A first application may receive a request for data from a second application. The first application may generate a first URL to the second application, a parameter of the first URL comprising an identifier of the first application. A mobile operating system may access the first URL to open the second application. The second application may validate credentials for an account and initiate a server on a port. The second application may generate a second URL to the first application, a parameter of the second URL comprising the port. The operating system may access the second URL to open the first application. The first application may establish a connection with the server using the port specified in the second URL and receive data from the second application via the connection with the server.

Abstract: A fluid end for a fracturing pump includes a plurality of segments coupled together along a discharge axis, each segment of the plurality of segments having a plurality of suction bores. The fluid end also includes respective interfaces between segment pairs formed by adjacent segments of the plurality of segments, the interfaces coupling the segment pairs together. The fluid end further includes respective access areas proximate the respective interfaces, the respective access areas configured to provide access for mechanical couplings to join the segment pairs together.

Abstract: A system for interfacing with a decisioning service from a third-party domain. A backend system may receive a request to interface with the decisioning service to generate a prequalification result for a user for a specified product, in response to the actuation of a button included in a third-party web domain rendering a product. The backend system may execute a call on a website of the decisioning service. The backend system may receive the product information from the button. The backend system may generate the website within the third-party domain, including a request for information about the user, in response to executing the call to the website. The backend system may transmit a request for generating prequalification result for the product to the decisioning service. The backend system may receive the prequalification result from the decisioning service.

Abstract: Methods and systems are described herein for improving anomaly detection in timeseries datasets. Different machine learning models may be trained to process specific types of timeseries data efficiently and accurately. Thus, selecting a proper machine learning model for identifying anomalies in a specific set of timeseries data may greatly improve accuracy and efficiency of anomaly detection. Another way to improve anomaly detection is to process a multitude of timeseries datasets for a time period (e.g., 90 days) to detect anomalies from those timeseries datasets and then correlate those detected anomalies by generating an anomaly timeseries dataset and identifying anomalies within the anomaly timeseries dataset. Yet another way to improve anomaly detection is to divide a dataset into multiple datasets based on a type of anomaly detection requested.

Abstract: In some embodiments, a profile associated with a user may indicate one or more data types and at least one profile-specific format associated with each of the data types. In response to detecting a document in a camera view, the document may be parsed to identify input fields that correspond to at least one data type of the profile. In response to identifying an input field that requires a format different from a profile-specific format, an input field rendering corresponding to the profile-specific format may be presented on an augmented reality view over the input field. In response to obtaining a user input related to the input field, the input field rendering may be updated in the augmented reality view to depict the user input in the profile-specific format, and the user input in the format required for the input field may be provided to the input field.

Abstract: This disclosure presents a process for communications in a borehole containing a fluid or drilling mud, where a conventional mud pulser can be utilized to transmit data to a transducer. The transducer, or a communicatively coupled computing system, can perform pre-processing steps to correct the received data using an average of a moving time window of the received data, and then normalize the corrected data. The corrected data can then be utilized as inputs into a machine learning mud pulse recognition network where the data can be classified and an ideal or clean pulse waveform can be overlaid the corrected data. The overlay and the corrected data can be fed into a conventional decoder or decoded by the disclosed process. The decoded data can then be communicated to another system and used as inputs, such as to a well site controller to enable adjustments to well site operation parameters.

Abstract: In an embodiment, a method includes receiving information identifying an input bot for testing. The method also includes detecting a functionality performed by the input bot. The method also includes creating a plurality of inputs for simulation of the functionality of the input bot. The method also includes executing the input bot a plurality of times using a same sample of actions. The method also includes checking for consistency of at least one of behavior and output for the same sample of actions. The method also includes executing the input bot a plurality of times using different samples of actions. The method also includes generating an execution plan for the input bot. The method also includes automatically validating the input bot, where the validation results in an automated determination of whether the input bot is defective.

Abstract: A process for combining domain restriction and remote authentication may include receiving a token from a plug-in application to conduct a transaction associated with a user of a communicating device. The process may include sending an authentication request to a remote access control sever to authenticate the user, and receiving, from the remote access control server, an authentication tracking value that the remote access control server used in generation of an authentication cryptogram. The process may also include generating, using the authentication tracking value, a domain restriction cryptogram that is used for domain restriction of the token, and sending, to the plug-in application, the domain restriction cryptogram.

Abstract: An assembly for a container to be filled with a pharmaceutical drug is provided. The assembly includes a first component and a second component. The first component has at least one electronic device fully embedded therein, a first end provided with a first engagement feature and an opposing second end. The second component has a second engagement feature configured to engage the first engagement feature of the first component.

Abstract: A tool adapter includes a body, which is elongated along a first axis. The body includes at least a first side surface that is opposite to the second side surface, as well as a first end surface that is opposite to the second end surface. The body includes a first input drive connector, which is located at a middle section of the body and which is accessible from the first side surface. The first input drive connector is structured to mate with a first drive part of a torque wrench such that a longitudinal axis of the torque wrench is parallel to the first axis when the torque wrench is connected to the adapter. The body includes a first output drive connector that is located at a middle region of the first end surface. The first output drive connector is structured to mate with a first connector part of a tool head such that a longitudinal axis of the tool head is parallel to the first axis when the tool head is connected to the adapter. The first input drive connector is defined to be a first size.

Abstract: A computer-implemented method, a computing system, and a computer program product for generating new items compatible with given items may use data associated with a plurality of images and random noise data associated with a random noise image to train an adversarial network including a series of generator networks and a series of discriminator networks corresponding to the series of generator networks by modifying, using a loss function of the adversarial network that depends on a compatibility of the images, one or more parameters of the series of generator networks. The series of generator networks may generate a generated image associated with a generated item different than the given items.

Abstract: A device may receive, from a payment processor server device, a transaction card number and a network address of a client device, wherein the transaction card number and the client device are associated with a customer attempting to conduct an online transaction with a merchant via a merchant server device. The device may process the transaction card number and the network address, with a machine learning model, to determine whether to approve or deny the online transaction. The device may selectively provide, to the client device and the merchant server device, data indicating that the online transaction is approved when the machine learning model determines to approve the online transaction, or provide, to the client device and the merchant server device, data indicating that the online transaction is denied when the machine learning model determines to deny the online transaction.

Abstract: Systems and methods for using accelerations derived from a motion pattern for multi-factor authentication, the method including receiving, filtering, and determining an identifying pattern from acceleration data representative of the user and using the identifying pattern for secured access authentication.

Abstract: Logging downhole exposes components of logging tools, for example, antennas to abrasive and erosive operating conditions. A protective sleeve may disposed about an antenna assembly to protect the antenna assembly for the downhole operating conditions. To permit transmission and receipt of signals by and too the antenna assembly, slots are formed or disposed in the protective sleeve. A non-conductive composite insert is formed in the slots to protect the internal components of the protective sleeve, for example, the antenna assembly, from the operation conditions. A non-conductive composite inner liner is formed in an annulus of the protective sleeve and adheres to the protective sleeve and the non-conductive composite insert. The non-conductive component insert and inner liner allow signals to be transmitted and received by the antenna assembly so that logging operations can be completed without undue delay and the expense of repairing or replacing worn or damaged components.

Abstract: Embodiments of the present invention use a limited-use public/private key pair to encrypt and decrypt messages sent through an intermediary. The messages may contain sensitive information and may be transmitted between entities over one or more networks. In some embodiments, the entities and/or the networks may be untrusted. Nevertheless, the content of the messages may remain protected by virtue of the limited-use key pair infrastructure.

Abstract: An apparatus for measuring mechanical properties of a rock formation. The apparatus includes force application fixtures configured to apply opposing compressive forces to a disc-shaped sample of a core plug specimen from the rock formation. Each of the force application fixtures include an applicant portion having an end cap. The end cap has a shaped surface that is configured to conform with a portion of a non-planar side of the disc-shaped sample such that substantially an entire volume of the disc-shaped sample experiences a compressive stress when the opposing compressive forces are applied to the portions of the non-planar side. A system and method for measuring mechanical properties of a rock formation are also disclosed.

Abstract: Multiple on-line coupons are automatically tested on items of interest to a customer, without requiring the customer to perform any action or to look for such coupons in various sources. Such testing can be automatically initiated and performed on items within the customer's shopping cart. Alternatively or additionally, testing can be automatically initiated and performed while the customer is browsing a page for an item on an e-commerce website, before the customer has even placed items in his or her shopping cart. The best coupon or coupons are then presented to the customer, or automatically applied to provide the customer with the appropriate discounts.

Abstract: Disclosed herein are systems and methods that may generate so-called “honey credentials” that are transmitted to a “phishing” website, and are then stored into a honey credential database. The honey credentials appear to be valid credentials, but whenever a bad actor attempts to access an enterprise using the honey credentials, security appliances the enterprise may update the records of the honey credential database to include one or more unique identifiers for each bad actor device that attempts to access the enterprise network using the honey credentials. A server may automatically query the honey credential database to identify other accounts that have been accessed by devices that used the honey credentials to access the enterprise. The server may then flag the accounts and restrict their functionality.