Patents Assigned to Seton Hall University
  • Publication number: 20210277279
    Abstract: Photoactive polymer coatings and methods of making the same are disclosed herein. In some embodiments, a polymer coating having a porous structure extending throughout the polymer coating, wherein the porous structure is present at an exposed surface of the polymer coating creating a roughened surface, wherein the polymer of the polymer coating is a siloxane based polymer; and a modified support particle disposed within the polymer coating, wherein the modified support particle includes a substituted phthalocyanine and a support particle. In some embodiments, the substituted phthalocyanine is a halogenated phthalocyanine.
    Type: Application
    Filed: May 24, 2021
    Publication date: September 9, 2021
    Applicant: Seton Hall University
    Inventors: James E. Hanson, Abdul Azeez, Sergiu M. Gorun
  • Patent number: 11015032
    Abstract: Photoactive polymer coatings and methods of making the same are disclosed herein. In some embodiments, a polymer coating comprises a polymer matrix having a porous structure extending throughout the polymer matrix, wherein the porous structure is present at an exposed surface of the polymer coating creating a roughened surface, and a modified support particle disposed within the polymer matrix, wherein the modified support particle includes a substituted phthalocyanine and a support particle. In some embodiments, the substituted phthalocyanine is a halogenated phthalocyanine.
    Type: Grant
    Filed: February 28, 2019
    Date of Patent: May 25, 2021
    Assignee: Seton Hall University
    Inventors: James E. Hanson, Abdul Azeez, Sergiu M. Gorun
  • Patent number: 10942142
    Abstract: Methods and apparatus for detecting an analyte using fluorinated phthalocyanines is disclosed herein. A method for detecting an analyte includes illuminating an analyte solution which contacts an electrode comprising a conductive material having a photosensitizer coupled thereto to generate a reactive oxygen species, wherein the photosensitizer is a fluorinated pthalocyanine having a metal or a non-metal center, oxidizing an analyte present in the analyte solution with the reactive oxygen species to form an oxidized analyte, and detecting a current resulting from the reduction of the oxidized analyte at the electrode.
    Type: Grant
    Filed: July 13, 2018
    Date of Patent: March 9, 2021
    Assignees: Seton Hall University
    Inventors: Karolien De Wael, Sergiu M. Gorun, Stanislav Trashin, Erik N. Carrión
  • Publication number: 20190270858
    Abstract: Photoactive polymer coatings and methods of making the same are disclosed herein. In some embodiments, a polymer coating comprises a polymer matrix having a porous structure extending throughout the polymer matrix, wherein the porous structure is present at an exposed surface of the polymer coating creating a roughened surface, and a modified support particle disposed within the polymer matrix, wherein the modified support particle includes a substituted phthalocyanine and a support particle. In some embodiments, the substituted phthalocyanine is a halogenated phthalocyanine.
    Type: Application
    Filed: February 28, 2019
    Publication date: September 5, 2019
    Applicant: Seton Hall University
    Inventors: James E. Hanson, Abdul Azeez, Sergiu M. Gorun
  • Publication number: 20190017955
    Abstract: Methods and apparatus for detecting an analyte using fluorinated phthalocyanines is disclosed herein. A method for detecting an analyte includes illuminating an analyte solution which contacts an electrode comprising a conductive material having a photosensitizer coupled thereto to generate a reactive oxygen species, wherein the photosensitizer is a fluorinated pthalocyanine having a metal or a non-metal center, oxidizing an analyte present in the analyte solution with the reactive oxygen species to form an oxidized analyte, and detecting a current resulting from the reduction of the oxidized analyte at the electrode.
    Type: Application
    Filed: July 13, 2018
    Publication date: January 17, 2019
    Applicants: Seton Hall University, AXES Research Group, Department of Chemistry, University of Antwerp,
    Inventors: Karolien De Wael, Sergiu M. Gorun, Stanislav Trashin, Erik N. Carrión
  • Patent number: 9956549
    Abstract: A new class of organic-inorganic hybrid composite materials, composites of a fluoroalkyl fluorophthalocyanine and a solid-state support containing an imidazole group. The new class of composite materials can be used as a heterogeneous catalyst for the heterogeneous oxidation organic molecules in aqueous and some organic solvents systems is claimed.
    Type: Grant
    Filed: February 26, 2016
    Date of Patent: May 1, 2018
    Assignee: Seton Hall University
    Inventors: Hemantbhai Patel, Sergiu M. Gorun
  • Patent number: 9950276
    Abstract: Disclosed are methods of extracting water from a composition of an organic liquid and water, using a polyol which causes a phase separation.
    Type: Grant
    Filed: December 22, 2016
    Date of Patent: April 24, 2018
    Assignee: Seton Hall University
    Inventors: John R. Sowa, Wyatt R. Murphy, Jr., Mithilesh Desphande
  • Patent number: 9731284
    Abstract: A process for use of composite catalysts for oxidation of amines during synthesis of energetic compounds. This method overcomes the safety concerns associated with dangerous reaction conditions for these energetic materials. The process requires exposing phthalocyanine conjugated to an inorganic substrate to the precursor reactant and activating the composite material to light and oxygen to covert amine groups into oxidized nitrogen species.
    Type: Grant
    Filed: February 24, 2016
    Date of Patent: August 15, 2017
    Assignees: The United States of America as Represented by the Secretary of the Army, Seton Hall University
    Inventors: Peggy A. Sanchez, Kimberly Griswold, Sergiu M. Gorun, Hemantbhai H. Patel
  • Publication number: 20170095754
    Abstract: Disclosed are methods of extracting water from a composition of an organic liquid and water, using a polyol which causes a phase separation.
    Type: Application
    Filed: December 22, 2016
    Publication date: April 6, 2017
    Applicant: Seton Hall University
    Inventors: John R. Sowa, Wyatt R. Murphy, JR., Mithilesh Desphande
  • Patent number: 9572898
    Abstract: Functionalized fluorine containing phthalocyanine molecules, methods of making, and methods of use in diagnostic applications and disease treatment are disclosed herein. In some embodiments, the fluorine containing phthalocyanine molecules are functionalized with a reactive functional group or at least one cancer-targeting ligand (CTL). The CTL can facilitate more efficient binding and/or internalization to a cancer cell than to a healthy cell. The CTL can inhibit expression of oncoprotein in some embodiments. The pthalocyanine moiety can be used in diagnostic applications, such as fluorescence labeling of a cancer cell, and/or treatment applications, such as catalyzing formation of a reactive oxygen species (ROS) which can contribute to cell death of a cancer cell.
    Type: Grant
    Filed: September 9, 2014
    Date of Patent: February 21, 2017
    Assignee: Seton Hall University
    Inventors: David Sabatino, Sergiu M. Gorun, Emily Borland, Hemantbhai Patel, Pradeepkumar Patel, Erik Nathaniel Carrión
  • Patent number: 9545583
    Abstract: Disclosed are methods of extracting water from a composition of an organic liquid and water, using a polyol.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: January 17, 2017
    Assignee: Seton Hall University
    Inventors: John R. Sowa, Jr., Wyatt R. Murphy, Jr., Mithilesh Deshpande
  • Publication number: 20140263050
    Abstract: Disclosed are methods of extracting water from a composition of an organic liquid and water, using a polyol.
    Type: Application
    Filed: March 13, 2014
    Publication date: September 18, 2014
    Applicant: SETON HALL UNIVERSITY
    Inventors: John R. Sowa, JR., Wyatt R. Murphy, JR., Mithilesh Deshpande
  • Patent number: 8222218
    Abstract: Disclosed are cyclopropanated carbohydrate compounds of formulas I and II: Also disclosed are methods of treating or preventing a central nervous system ailment by administering to an organism in need thereof an effective amount of a cyclopropanated carbohydrate compound of formula I or II and pharmaceutical compositions containing a cyclopropanated carbohydrate compound of formula I or II.
    Type: Grant
    Filed: March 27, 2009
    Date of Patent: July 17, 2012
    Assignee: Seton Hall University
    Inventors: Cecilia H. Marzabadi, Ian Jamie Talisman
  • Patent number: 6136746
    Abstract: A supported catalyst comprising a support, an anchoring agent such as an isopoly-oxymetal anion or oxometal salt thereof, and a metal complex which is useful in a wide variety on organic reactions, especially the hydrogenation of substituted .alpha.,.beta. unsaturated acids and esters, is provided. Various methods of preparing the supported catalyst of the present invention is also disclosed.
    Type: Grant
    Filed: June 11, 1998
    Date of Patent: October 24, 2000
    Assignee: Seton Hall University
    Inventors: Setrak K. Tanielyan, Robert L. Augustine
  • Patent number: 6025295
    Abstract: A supported catalyst comprising a support, an anchoring agent such as a heteropoly acid or anion, and a metal complex which is useful in a wide variety on organic reactions, especially the hydrogenation of substituted .alpha., .beta. unsaturated acids and esters, is provided. Various methods of preparing the supported catalyst of the present invention is also disclosed.
    Type: Grant
    Filed: December 18, 1997
    Date of Patent: February 15, 2000
    Assignee: Seton Hall University
    Inventors: Setrak K. Tanielyan, Robert L. Augustine
  • Patent number: 6005148
    Abstract: A supported catalyst comprising a support, an anchoring agent such as a heteropoly acid or anion, and a metal complex which is useful in a wide variety on organic reactions, especially the hydrogenation of substituted .alpha.,.beta. unsaturated acids and esters, is provided. Various methods of preparing the supported catalyst of the present invention is also disclosed.
    Type: Grant
    Filed: November 17, 1998
    Date of Patent: December 21, 1999
    Assignee: Seton Hall University
    Inventors: Setrak K. Tanielyan, Robert L. Augustine