Abstract: There is provided a stable vaccine for providing protection against disease having viral proteins transgenically expressed in plant cells. Also provided is a stable vaccine which provides protection against disease containing viral protein and coding sequences cloned into an E. coli expression system. A method of vaccination by transgenically expressing viral proteins capable of providing protection against disease into plant cells and administering the plant cells to an animal in need of vaccination is also provided. Also provided is a method of vaccination by cloning viral protein and coding sequences capable of providing protection against disease into an E. coli expression system and administering the E. coli into the animal in need of vaccination.
Type:
Grant
Filed:
January 4, 2000
Date of Patent:
March 4, 2003
Assignees:
Shafit
Inventors:
Yehuda Stram, Arie Rogel, Ilan Sela, Orit Edelbaum, Yehoshua Shachar, Yehuda Zanberg, Tanya Gontmakher, Eli Khayat