Patents Assigned to SHANDONG DANHONG PHARMACEUTICAL CO., LTD.
  • Patent number: 11897830
    Abstract: An amorphous form of dezocine analogue hydrochloride is represented by formula (II). An X-ray powder diffraction spectrum of the amorphous form is shown in FIG. 1.
    Type: Grant
    Filed: May 6, 2022
    Date of Patent: February 13, 2024
    Assignee: SHANDONG DANHONG PHARMACEUTICAL CO., LTD.
    Inventors: Yang Zhang, Wentao Wu, Zhixiang Li
  • Patent number: 11339119
    Abstract: The present invention relates to a crystal form and an amorphous form of dezocine analogue hydrochloride, and in particularly, to a crystal form of a compound represented by formula (I) and an amorphous form of a compound represented by formula (II). An X-ray powder diffraction spectrum of the crystal form comprises characteristic peaks at 2? values of 13.1°±0.2°, 16.8±0.2°, and 18.5±0.2°, and an X-ray powder diffraction spectrum of the amorphous form is shown in FIG. 1.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: May 24, 2022
    Assignee: SHANDONG DANHONG PHARMACEUTICAL CO., LTD.
    Inventors: Yang Zhang, Wentao Wu, Zhixiang Li
  • Patent number: 10858322
    Abstract: Disclosed are a method for preparing an imidazole derivative and crystal form A and crystal form B thereof, and also disclosed is a method for preparing a compound of formula (I) and an intermediate thereof.
    Type: Grant
    Filed: March 20, 2020
    Date of Patent: December 8, 2020
    Assignee: SHANDONG DANHONG PHARMACEUTICAL CO., LTD.
    Inventors: Weihua Shi, Feng Xu, Zheng Wang, Weidong Li, Linghui Wu, Hongwei Li, Minggao Zeng, Kunmin Lai, Zhigan Jiang, Haiying He
  • Patent number: 10744109
    Abstract: Disclosed are a sustained release suspension containing dezocine analogue ester and a preparation method therefor. According to the present invention, an injectable oily auxiliary material which may pharmaceutically serve as a sustained-release depot and an excipient are selected, and micronization technology is used jointly with high pressure homogenization technology and an anti-solvent technique to prepare an injectable long-acting suspension. The main components of the suspension are a compound represented by formula (I), the injectable oil, and the like.
    Type: Grant
    Filed: August 7, 2018
    Date of Patent: August 18, 2020
    Assignee: SHANDONG DANHONG PHARMACEUTICAL CO., LTD.
    Inventors: Yang Zhang, Bing Deng, Jiahu Wu, Wentao Wu, Zhixiang Li
  • Publication number: 20200223802
    Abstract: Disclosed are a method for preparing an imidazole derivative and crystal form A and crystal form B thereof, and also disclosed is a method for preparing a compound of formula (I) and an intermediate thereof.
    Type: Application
    Filed: March 20, 2020
    Publication date: July 16, 2020
    Applicant: SHANDONG DANHONG PHARMACEUTICAL CO., LTD.
    Inventors: Weihua SHI, Feng XU, Zheng WANG, Weidong LI, Linghui WU, Hongwei LI, Minggao ZENG, Kunmin LAI, Zhigan JIANG, Haiying HE
  • Patent number: 10633347
    Abstract: Disclosed are a method for preparing an imidazole derivative and crystal form A and crystal form B thereof, and also disclosed is a method for preparing a compound of formula (I) and an intermediate thereof.
    Type: Grant
    Filed: January 8, 2019
    Date of Patent: April 28, 2020
    Assignee: SHANDONG DANHONG PHARMACEUTICAL CO., LTD.
    Inventors: Weihua Shi, Feng Xu, Zheng Wang, Weidong Li, Linghui Wu, Hongwei Li, Minggao Zeng, Kunmin Lai, Zhigan Jiang, Haiying He
  • Patent number: 10414718
    Abstract: Disclosed in the present disclosure is a Dezocine analog, and particularly disclosed are compounds represented by formula (I), (II) and (III), a pharmaceutically acceptable salt or tautomer thereof.
    Type: Grant
    Filed: January 4, 2017
    Date of Patent: September 17, 2019
    Assignee: Shandong Danhong Pharmaceutical Co., Ltd.
    Inventors: Yang Zhang, Wentao Wu, Zhixiang Li, Guangwen Yang, Yongbo Fang, Tao Zhang, Wei Gu, Shuhui Chen, Fei Wang, Jian Li
  • Publication number: 20190218189
    Abstract: Disclosed are a method for preparing an imidazole derivative and crystal form A and crystal form B thereof, and also disclosed is a method for preparing a compound of formula (I) and an intermediate thereof.
    Type: Application
    Filed: January 8, 2019
    Publication date: July 18, 2019
    Applicant: SHANDONG DANHONG PHARMACEUTICAL CO., LTD.
    Inventors: Weihua SHI, Feng XU, Zheng WANG, Weidong LI, Linghui WU, Hongwei LI, Minggao ZENG, Kunmin LAI, Zhigan JIANG, Haiying HE
  • Patent number: 10227309
    Abstract: Disclosed are a method for preparing an imidazole derivative and crystal form A and crystal form B thereof, and also disclosed is a method for preparing a compound of formula (I) and an intermediate thereof.
    Type: Grant
    Filed: June 7, 2016
    Date of Patent: March 12, 2019
    Assignee: SHANDONG DANHONG PHARMACEUTICAL CO., LTD.
    Inventors: Weihua Shi, Feng Xu, Zheng Wang, Weidong Li, Linghui Wu, Hongwei Li, Minggao Zeng, Kunmin Lai, Zhigan Jiang, Haiying He
  • Patent number: 10030029
    Abstract: Disclosed are an antiviral compound and a use thereof in the preparation of a medicament for the treatment of virus infections. Specifically, the present invention relates an imidazole derivative for treating respiratory syncytial virus infection.
    Type: Grant
    Filed: September 19, 2017
    Date of Patent: July 24, 2018
    Assignee: Shandong Danhong Pharmaceutical Co., Ltd.
    Inventors: Haiying He, Weihua Shi, Zhigan Jiang, Lixia Han, Jikui Sun, Jian Li, Shuhui Chen
  • Publication number: 20180141915
    Abstract: Disclosed are a method for preparing an imidazole derivative and crystal form A and crystal form B thereof, and also disclosed is a method for preparing a compound of formula (I) and an intermediate thereof.
    Type: Application
    Filed: June 7, 2016
    Publication date: May 24, 2018
    Applicant: SHANDONG DANHONG PHARMACEUTICAL CO., LTD.
    Inventors: Weihua SHI, Feng XU, Zheng WANG, Weidong LI, Linghui WU, Hongwei LI, Minggao ZENG, Kunmin LAI, Zhigan JIANG, Haiying HE
  • Publication number: 20180009820
    Abstract: Disclosed are an antiviral compound and a use thereof in the preparation of a medicament for the treatment of virus infections. Specifically, the present invention relates an imidazole derivative for treating respiratory syncytial virus infection.
    Type: Application
    Filed: September 19, 2017
    Publication date: January 11, 2018
    Applicant: Shandong Danhong Pharmaceutical Co., Ltd.
    Inventors: Haiying He, Weihua Shi, Zhigan Jiang, Lixia Han, Jikui Sun, Jian Li, Shuhui Chen
  • Patent number: 9850251
    Abstract: Disclosed are an antiviral compound and a use thereof in the preparation of a medicament for the treatment of virus infections. Specifically, the present invention relates an imidazole derivative for treating respiratory syncytial virus infection.
    Type: Grant
    Filed: November 11, 2014
    Date of Patent: December 26, 2017
    Assignee: SHANDONG DANHONG PHARMACEUTICAL CO., LTD.
    Inventors: Haiying He, Weihua Shi, Zhigan Jiang, Lixia Han, Jikui Sun, Jian Li, Shuhui Chen