Patents Assigned to SHANGHAI ALLIST PHARMACEUTICAL AND MEDICAL TECH CO
  • Crystalline forms of mesylate salt of pyridinyl amino pyrimidine derivative, preparation methods therefor, and applications thereof
    Patent number: 10550101
    Abstract: Forms I and II of the mesylate salt of the compound of formula (I), a preparation methods thereof, a pharmaceutical composition containing the crystal forms, and the use of the crystal forms in treating diseases mediated by activating and resistance mutations of EGFR, in particular cancer, in mammal, in particular in human.
    Type: Grant
    Filed: March 1, 2017
    Date of Patent: February 4, 2020
    Assignee: SHANGHAI ALLIST PHARMACEUTICAL AND MEDICAL TECH CO
    Inventors: Huibing Luo, Qiang Zhang
  • Salt of pyridinyl amino pyrimidine derivative, preparation method therefor, and application thereof
    Patent number: 10472349
    Abstract: A mesylate salt of the compound of formula (I), the preparation method thereof, a pharmaceutical composition containing said salt and the use of said salt in treating diseases mediated by activating and resistance mutations of EGFR, in particular cancers, in mammal, in particular human. The mesylate salt of the compound of formula (I) has a high bioavailability in animal, and can remarkably inhibit the growth of transplanted tumors in animal and show a good safety.
    Type: Grant
    Filed: March 1, 2017
    Date of Patent: November 12, 2019
    Assignee: SHANGHAI ALLIST PHARMACEUTICAL AND MEDICAL TECH CO
    Inventors: Huibing Luo, Huayong Zhou