Patents Assigned to Shanghai Aryl Pharmtec Co., Ltd.
  • PIPERAZINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20230373972
    Abstract: The present disclosure relates to a piperazine derivative, a preparation method therefor, and use thereof in medicine. Specifically, the present invention relates to a piperazine derivative represented by general formula (I), a preparation method therefor, and a pharmaceutically acceptable salt or prodrug thereof, and use thereof as a therapeutic agent, in particular, as an inhibitor of coagulation factor XIa (FXIa), wherein the definition of each substituent in general formula (I) is the same as that in the description.
    Type: Application
    Filed: September 16, 2021
    Publication date: November 23, 2023
    Applicants: Zhejiang Hisun Pharmaceutical Co., Ltd., Shanghai Aryl Pharmtec Co., Ltd.
    Inventors: Haibo QIU, Yutao MA, Ahuan CHEN, Yabo ZHU, Binhao ZHANG, Yongping LU, Cheng YE, Taishan HU, Wenjian QIAN, Lei CHEN