Patents Assigned to Shanghai Bio Road Gene Development, Ltd.
  • Patent number: 7273724
    Abstract: The present invention discloses a novel polypeptide—human actin-binding protein 54 and a polynucleotide encoding the same, as well as a method of producing the polypeptide by DNA recombinant technology. The present invention also discloses methods of using the polypeptide in treatment of various diseases, such as malignant tumor, blood disease, HIV infection, immunological diseases and various inflammation. The present invention also discloses an antagonist against the polypeptide and the therapeutic use of the same. The present invention also discloses the use of such polynucleotide encoding human actin-binding protein 54.
    Type: Grant
    Filed: November 20, 2000
    Date of Patent: September 25, 2007
    Assignee: Shanghai Bio Road Gene Development, Ltd.
    Inventors: Yumin Mao, Yi Xie
  • Patent number: 6994996
    Abstract: The invention discloses a novle human vacuolar H+-ATPase C subunit 42 and a polynucleotide encoding it. The invention also concerns a process of producing the polypeptide by recombinant DNA techniques. Methods are also disclosed for treating many diseases, e.g. malignant tumors, hemopathies, HIV infections, immune diseases and inflammations utilizing the ploypeptide. The invention discloses antagonists of the polypeptide and therapeutics comprising the same. The invention also discloses the uses of the polynucleotide, which encodes the human vacuolar H+-ATPase C subunit 42.
    Type: Grant
    Filed: October 27, 2000
    Date of Patent: February 7, 2006
    Assignee: Shanghai Bio Road Gene Development, Ltd.
    Inventors: Yumin Mao, Yi Xie
  • Patent number: 6984509
    Abstract: The present invention discloses a novel polypeptide, a steroid dehydrogenase 34, the polynucleotide encoding the polypeptide and the method for producing the polypetide by DNA recombinant technology. The invention also discloses the uses of the polypeptide in methods for tresting various diseases, such as steroid hormone dysbolismus disease, such as sex dysgenopathy, some endocrine and metabolic syndrome, viarous tumors of human reproductive system, bile acid dysbolismus, etc. The invention also discloses the agonists against the polypeptide and the therapeutic action thereof. The invention also discloses the uses of the polynucleotide encoding the novel steroid dehydrogenase 34.
    Type: Grant
    Filed: October 16, 2000
    Date of Patent: January 10, 2006
    Assignee: Shanghai Bio Road Gene Development, Ltd.
    Inventors: Yumin Mao, Yi Xie
  • Patent number: 6919431
    Abstract: The present invention discloses a novel polypeptide-Human SNARE protein 25 and polynucleotide encoding the same, as well as a method of producing the polypeptide by DNA recombinant technology. The present invention also discloses methods of using the polypeptide in treatment of various diseases, such as malignant tumor, blood disease, HIV infection, immunological disease and various inflammations. The present invention also discloses an antagonist against the polypeptide and the therapeutic use of the same. The present invention also discloses the use of such polynucleotide encoding Human SNARE protein 25.
    Type: Grant
    Filed: November 20, 2000
    Date of Patent: July 19, 2005
    Assignee: Shanghai Bio Road Gene Development, Ltd.
    Inventors: Yumin Mao, Yi Xie
  • Patent number: 6919427
    Abstract: The invention discloses a new kind of RNA binding protein 33 and polynucleotide encoding the polypeptide and a process for producing the polypeptide by recombinant methods. It also discloses the method of applying the polypeptide for the treatment of various kinds of diseases, such as cancer, hemopathology, HIV infection, immune diseases and inflammation. The antibody and antagonist of the polypeptide and the therapeutic use of the same is also disclosed. In addition, it refers to the use of polynucleotide encoding said RNA binding protein 33.
    Type: Grant
    Filed: October 16, 2000
    Date of Patent: July 19, 2005
    Assignee: Shanghai Bio Road Gene Development, Ltd.
    Inventors: Yumin Mao, Yi Xie
  • Patent number: 6919430
    Abstract: The present invention discloses a novel polypeptide-human galectin 15 and a polynucleotide encoding the same, as well as a method of producing the polypeptide by DNA recombinant technology. The present invention also discloses methods of using the polypeptide in treatment of various diseases, such as malignant tumor, blood disease, HIV infection, immunological disease and various inflammations. The present invention also discloses an antagonist against the polypeptide and the therapeutic use of the same.
    Type: Grant
    Filed: October 27, 2000
    Date of Patent: July 19, 2005
    Assignee: Shanghai Bio Road Gene Development, Ltd.
    Inventors: Yumin Mao, Yi Xie
  • Patent number: 6908765
    Abstract: The present invention discloses a novel polypeptide-human SR splicing factor 52 and polynucleotide encoding the same, as well as a method of producing the polypeptide by DNA recombinant technology. The present invention also discloses methods of using the polypeptide in treatment of various disease, such as malignant tumor, blood disease, HIV infection, immunological disease and various inflammation. The present invention also discloses an antagonist againts the polypeptide and the therapeutic use of the same. The present invention also discloses the use of such polynucleotide encoding Human SR splicing factor 52.
    Type: Grant
    Filed: November 20, 2000
    Date of Patent: June 21, 2005
    Assignee: Shanghai Bio Road Gene Development, Ltd.
    Inventors: Yumin Mao, Yi Xie
  • Patent number: 6811987
    Abstract: The present invention discloses a novel polypeptide, a human binding protein 42, the polynucleotide encoding the polypeptide and the method for producing the polypeptide by DNA recombinant technology. The invention also discloses the uses of the polypeptide in methods for treating various diseases, such as malignant tumour, hemopathy. HIV infection, immunological disease, and various inflammation, etc. The invention also discloses the agonists against the polypeptide and the therapeutic action thereof. The invention also discloses the uses of the polynucleotide encoding the novel human calcium binding protein 42.
    Type: Grant
    Filed: May 23, 2002
    Date of Patent: November 2, 2004
    Assignee: Shanghai Bio Road Gene Development, Ltd.
    Inventors: Yumin Mao, Yi Xie