Abstract: The present invention relates to a crystalline form of 1-(?-d-glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl]benzene. Specifically, it discloses a novel crystalline form of 1-(?-d-glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl]benzene and the preparation method as well as use thereof. The novel crystalline form of 1-(?-d-glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl]benzene provided in the present invention has the advantages such as stable physical and chemical properties, high purity, excellent reproducibility and industrial production suitability.
Abstract: A method to prepare Docetaxel trihydrate using the mixture of acetone and water, which provides the product with good stability, less experiment time, less exposal to light, and avoids purity decreasing. The process is simple and easy to operate.
Type:
Grant
Filed:
April 13, 2004
Date of Patent:
February 19, 2008
Assignees:
Shanghai Desano Chemical Pharmaceutical Co., Ltd., Shanghai Desano Pharmaceuticals Science & Technology Development Co., Ltd.
Abstract: A method to prepare Docetaxel trihydrate using the mixture of acetone and water, which provides the product with good stability, less experiment time, less exposal to light, and avoids purity decreasing. The process is simple and easy to operate.