Patents Assigned to Shanghai Desano Pharmaceutical Holding Co., Ltd.
  • Process for stereoselective synthesis of lamivudine
    Patent number: 8304540
    Abstract: The present invention discloses a process for stereoselective synthesis of Lamivudine comprising the following steps: (a) performing a glycosylation reaction between the compound of formula (I) and cytosine or protected cytosine, and separating the reaction product by recrystallization to obtain the intermediate of formula (II); and (b) deprotecting the intermediate of formula (II) to obtain Lamivudine.
    Type: Grant
    Filed: November 17, 2009
    Date of Patent: November 6, 2012
    Assignee: Shanghai Desano Pharmaceutical Holding Co., Ltd.
    Inventors: Jinliang Li, Feng Lv
  • PROCESS FOR STEREOSELECTIVE SYNTHESIS OF LAMIVUDINE
    Publication number: 20110118465
    Abstract: The present invention discloses a process for stereoselective synthesis of Lamivudine comprising the following steps: (a) performing a glycosylation-reaction between the compound of formula (I) and cytosine or protected cytosine, and separating the reaction product by recrystallization to obtain the intermediate of formula (II); and (b) deprotecting the intermediate of formula (II) to obtain Lamivudine.
    Type: Application
    Filed: November 17, 2009
    Publication date: May 19, 2011
    Applicant: Shanghai Desano Pharmaceutical Holding Co., Ltd.
    Inventors: Jinliang LI, Feng LV
  • PROCESS FOR STEREOSELECTIVE SYNTHESIS OF LAMIVUDINE
    Publication number: 20100249409
    Abstract: The present invention discloses a process for stereoselective synthesis of Lamivudine comprising the following steps: (a) performing a glycosylation-reaction between the compound of formula (I) and cytosine or protected cytosine, and separating the reaction product by recrystallization to obtain the intermediate of formula (II); and (b) deprotecting the intermediate of formula (II) to obtain Lamivudine.
    Type: Application
    Filed: November 17, 2009
    Publication date: September 30, 2010
    Applicant: Shanghai Desano Pharmaceutical Holding Co., Ltd.
    Inventors: Jinliang LI, Feng LV