Abstract: The invention relates to compositions and methods for treating or preventing disease or disorders caused by or associated with certain bacterial infection, especially Escherichia coli (E. coli) or Helicobacter pylori (H. pylori) infection. One exemplary compound of the present invention has the following formula I:
wherein n is 0 or 1, and R is selected from the group consisting of C1-10 alkyl, C6-10 aryl and
and wherein when n is 0, R is not C6-10 aryl.
Type:
Grant
Filed:
October 10, 2001
Date of Patent:
May 11, 2004
Assignees:
Shanghai East Best Biopharmaceutical, Nanjing University