Patents Assigned to SHANGHAI FOCHON PHARMACEUTICAL CO., LTD.
  • Sulfoximine, sulfonimidamide, sulfondiimine and diimidosulfonamide compounds as inhibitors of indoleamine 2,3-dioxygenase
    Patent number: 11168078
    Abstract: Provided are certain IDO inhibitors or pharmaceutically acceptable salts thereof which can inhibit enzymatic activity of indoleamine 2,3-dioxygenase (IDO) and may be useful for the treatment of diseases and disorders mediated by IDO. In addition, pharmaceutical compositions thereof and methods of use thereof are also provided.
    Type: Grant
    Filed: November 28, 2017
    Date of Patent: November 9, 2021
    Assignees: Shanghai Fochon Pharmaceutical Co., Ltd., Fochon Pharmaceuticals, Ltd.
    Inventors: Zhifang Chen, Rui Tan, Qihong Liu, Lijun Yang, Zhifu Li, Haohan Tan, Hongbin Liu, Xingdong Zhao, Min Lin, Jing Sun, Weibo Wang
  • MACROCYCLIC COMPOUNDS AS TRK KINASES INHIBITORS
    Publication number: 20210139506
    Abstract: Provided are certain TRK inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: March 27, 2019
    Publication date: May 13, 2021
    Applicants: Fochon Pharmaceuticals, Ltd., Shanghai Fochon Pharmaceutical Co., LTD.
    Inventors: Huajie ZHANG, Qihong LIU, Chengxi HE, Weipeng ZHANG, Rui TAN, Bin LIU, Hong FU, Haohan TAN, Lijun YANG, Hongbin LIU, Yunling WANG, Yuwei GAO, Zongyao ZOU, Yanxin LIU, Shu LIN, Tongshuang LI, Xingdong ZHAO, Weibo WANG
  • Indolizine derivatives, composition and methods of use
    Patent number: 10894038
    Abstract: Provided are certain URAT1 inhibitors, pharmaceutical compositions thereof, and methods of use therefor.
    Type: Grant
    Filed: December 26, 2016
    Date of Patent: January 19, 2021
    Assignees: SHANGHAI FOCHON PHARMACEUTICAL CO. LTD., FOCHON PHARMACEUTICALS, LTD.
    Inventors: Tongshuang Li, Xingdong Zhao, Chuiliang Yu, Haohan Tan, Xianlong Wang, Rui Tan, Bin Liu, Weipeng Zhang, Huajie Zhang, Qihong Liu, Zuwen Zhou, Zhifu Li, Yue Rong, Jing Sun, Weibo Wang
  • Certain protein kinase inhibitors
    Patent number: 10835535
    Abstract: Certain CDK4/6 inhibitors and pharmaceutically acceptable salts thereof are described. In particular, these compounds can inhibit kinase activity of CDK4/6 and may be useful for the treatment of hyper-proliferative diseases like cancer and inflammation. In addition, the pharmaceutical compositions thereof and methods of use thereof are also described.
    Type: Grant
    Filed: May 5, 2017
    Date of Patent: November 17, 2020
    Assignees: Shanghai Fochon Pharmaceutical Co., Ltd., Fochon Pharmaceuticals, Ltd.
    Inventors: Xingdong Zhao, Tongshuang Li, Zhifang Chen, Rui Tan, Ling Chen, Xianlong Wang, Lijun Yang, Zuwen Zhou, Yanxin Liu, Min Lin, Jing Sun, Weibo Wang
  • Substituted pyrrolo[2,3-d]pyridazin-4-ones and pyrazolo[3,4-d]pyridazin-4-ones as protein kinase inhibitors
    Patent number: 10800785
    Abstract: Provided are certain compounds or pharmaceutically acceptable salts thereof which can inhibit kinase activity of Bruton's tyrosine kinase (BTK) and may be useful for the treatment of diseases like cancer, immunological disease and inflammation.
    Type: Grant
    Filed: June 20, 2017
    Date of Patent: October 13, 2020
    Assignees: Shanghai Fochon Pharmaceutical Co., Ltd., Fochon Pharmaceuticals, Ltd.
    Inventors: Xingdong Zhao, Weipeng Zhang, Zhifang Chen, Ling Chen, Xianlong Wang, Zhifu Li, Rui Tan, Lijun Yang, Haohan Tan, Bin Liu, Kai Ran, Zongyao Zou, Min Lin, Jing Sun, Weibo Wang
  • COMPOUNDS AS BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS
    Publication number: 20190345156
    Abstract: Bcl-2 inhibitors, pharmaceutical compositions thereof, and methods of use thereof are provided. In particular, Bcl-2 inhibitors of formula (I) are provided, wherein the variable groups are as defined in the specification. The Bc1-2 inhibitors can be used to treat cell proliferative disorders.
    Type: Application
    Filed: January 5, 2018
    Publication date: November 14, 2019
    Applicants: Shanghai Fochon Pharmaceutical Co., Ltd., Fochon Pharmaceuticals, Ltd.
    Inventors: Xingdong ZHAO, Zuwen ZHOU, Chengxi HE, Zhifu LI, Yue RONG, Rui TAN, Huajie ZHANG, Hongbin LIU, Weipeng ZHANG, Haohan TAN, Zhifang CHEN, Lihua JIANG, Yanxin LIU, Min LIN, Jing SUN, Weibo WANG
  • Certain protein kinase inhibitor
    Patent number: 10450316
    Abstract: Provided are certain CDK4/6 inhibitors with the structure of formula (I), pharmaceutical compositions thereof, and methods of use therefor. The compounds are of the class of pyrimidin-2 amine derivatives, useful for the treatment of hyper-proliferative diseases.
    Type: Grant
    Filed: April 28, 2016
    Date of Patent: October 22, 2019
    Assignees: CHONGQING FOCHON PHARMACEUTICAL CO., LTD., SHANGHAI FOCHON PHARMACEUTICAL CO., LTD.
    Inventors: Xingdong Zhao, Tongshuang Li, Haohan Tan, Zhifang Chen, Ling Chen, Qihong Liu, Yue Rong, Lijun Yang, Xianlong Wang, Rui Tan, Zuwen Zhou, Bin Liu, Min Lin, Lihua Jiang, Yanxin Liu, Li Linghu, Jing Sun, Weibo Wang
  • Certain protein kinase inhibitors
    Patent number: 10328060
    Abstract: Provided are certain PI3K inhibitors, pharmaceutical compositions thereof, and methods of use therefor.
    Type: Grant
    Filed: November 1, 2015
    Date of Patent: June 25, 2019
    Assignees: SHANGHAI FOCHON PHARMACEUTICAL CO., LTD., SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES, CHONGQING FOCHON PHARMACEUTICAL CO., LTD.
    Inventors: Xingdong Zhao, Jian Ding, Linghua Meng, Meiyu Geng, Tongshuang Li, Zuwen Zhou, Ling Chen, Qihong Liu, Xianlong Wang, Lijun Yang, Yue Rong, Rui Tan, Chuiliang Yu, Lihua Jiang, Yanxin Liu, Li Linghu, Jing Sun, Weibo Wang
  • SUBSTITUTED PYRROLO [2, 3-D] PYRIDAZIN-4-ONES AND PYRAZOLO [3, 4-D] PYRIDAZIN-4-ONES AS PROTEIN KINASE INHIBITORS
    Publication number: 20190161489
    Abstract: Provided are certain compounds or pharmaceutically acceptable salts thereof which can inhibit kinase activity of Bruton's tyrosine kinase (BTK) and may be useful for the treatment of diseases like cancer, immunological disease and inflammation.
    Type: Application
    Filed: June 20, 2017
    Publication date: May 30, 2019
    Applicants: Shanghai Fochon Pharmaceutical Co., Ltd., Fochon Pharmaceuticals, Ltd.
    Inventors: Xingdong ZHAO, Weipeng ZHANG, Zhifang CHEN, Ling CHEN, Xianlong WANG, Zhifu LI, Rui TAN, Lijun YANG, Haohan TAN, Bin LIU, Kai RAN, Zongyao ZOU, Min LIN, Jing SUN, Weibo WANG
  • Certain protein kinase inhibitors
    Patent number: 10087195
    Abstract: Provided are compound of formula (I) as certain CDK4/6 inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Grant
    Filed: May 27, 2015
    Date of Patent: October 2, 2018
    Assignees: SHANGHAI FOCHON PHARMACEUTICAL CO., LTD., CHONGQING FOCHON PHARMACEUTICAL CO., LTD.
    Inventors: Weibo Wang, Xingdong Zhao, Tongshuang Li, Qiang Tian, Huajie Zhang, Haohan Tan, Xianlong Wang, Qihong Liu, Zhifu Li, Weipeng Zhang, Zhifang Chen, Lihua Jiang, Yanxin Liu, Li Linghu, Min Lin, Jing Sun
  • Quinazoline derivatives, compositions thereof, and use as pharmaceuticals
    Patent number: 10053449
    Abstract: Disclosed herein are protein kinase inhibitors, more particularly novel quinazoline derivatives and pharmaceutical compositions thereof, and method of use thereof.
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: August 21, 2018
    Assignee: Shanghai Fochon Pharmaceutical Co., Ltd.
    Inventors: Weibo Wang, Xingdong Zhao, Tongshuang Li, Qiang Tian, Ling Chen, Zuwen Zhou, Zhifu Li, Xianlong Wang, Yue Rong, Lihua Jiang, Yanxin Liu, Jing Sun, Fanxin Zeng
  • Certain protein kinase inhibitors
    Patent number: 10022374
    Abstract: Disclosed herein are protein kinase inhibitors, more particularly pyridazine derivatives and pharmaceutical compositions thereof, and method of use thereof.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: July 17, 2018
    Assignee: Shanghai Fochon Pharmaceutical Co., Ltd.
    Inventors: Weibo Wang, Xingdong Zhao, Quan Yuan, Hailong Shi, Qiang Tian, Qihong Liu, Zuwen Zhou, Xianlong Wang, Zhifang Chen, Ling Chen, Haohan Tan, Bo Fang, Lihua Jiang, Yanxin Liu, Jing Sun, Fanxin Zeng, Tongshuang Li
  • CERTAIN PROTEIN KINASE INHIBITORS
    Publication number: 20180036293
    Abstract: Provided are certain PI3K inhibitors, pharmaceutical compositions thereof, and methods of use therefor.
    Type: Application
    Filed: November 1, 2015
    Publication date: February 8, 2018
    Applicants: Shanghai Fochon Pharmaceutical Co., Ltd., Shanghai Institute of Materia Medica Chinese Academy of Sciences, ChongQing Fochon Pharmaceutical Co., Ltd.
    Inventors: Xingdong ZHAO, Jian DING, Linghua MENG, Meiyu GENG, Tongshuang LI, Zuwen ZHOU, Ling CHEN, Qihong LIU, Xianlong WANG, Lijun YANG, Yue RONG, Rui TAN, Chuiliang YU, Lihua JIANG, Yanxin LIU, Li LINGHU, Jing SUN, Weibo WANG
  • Quinazoline derivatives, compositions thereof, and use as pharmaceuticals
    Patent number: 9714235
    Abstract: Disclosed herein are protein kinase inhibitors, more particularly novel quinazoline derivatives and pharmaceutical compositions thereof, and method of use thereof.
    Type: Grant
    Filed: July 17, 2014
    Date of Patent: July 25, 2017
    Assignee: Shanghai Fochon Pharmaceutical Co., Ltd.
    Inventors: Weibo Wang, Xingdong Zhao, Tongshuang Li, Qiang Tian, Ling Chen, Zuwen Zhou, Zhifu Li, Xianlong Wang, Yue Rong, Lihua Jiang, Yanxin Liu, Jing Sun, Fanxin Zeng
  • Certain protein kinase inhibitors
    Patent number: 9567342
    Abstract: Disclosed herein are protein kinase inhibitors, more particularly novel pyrimidine derivatives and pharmaceutical compositions thereof, and method of use thereof.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: February 14, 2017
    Assignees: SHANGHAI FOCHON PHARMACEUTICAL CO., LTD., SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES
    Inventors: Weibo Wang, Meiyu Geng, Jian Ding, Xingdong Zhao, Jing Ai, Qiang Tian, Xia Peng, Weipeng Zhang, Hongbin Liu, Haohan Tan, Ling Chen
  • Certain protein kinase inhibitors
    Patent number: 9556171
    Abstract: Disclosed herein are protein kinase inhibitors, more particularly pyridazine derivatives and pharmaceutical compositions thereof, and method of use thereof.
    Type: Grant
    Filed: April 18, 2014
    Date of Patent: January 31, 2017
    Assignee: Shanghai Fochon Pharmaceutical Co., Ltd.
    Inventors: Weibo Wang, Xingdong Zhao, Quan Yuan, Hailong Shi, Qiang Tian, Qihong Liu, Zuwen Zhou, Xianlong Wang, Zhifang Chen, Ling Chen, Haohan Tan, Bo Fang, Lihua Jiang, Yanxin Liu, Jing Sun, Fanxin Zeng, Tongshuang Li
  • QUINAZOLINE DERIVATIVES, COMPOSITIONS THEREOF, AND USE AS PHARMACEUTICALS
    Publication number: 20160168129
    Abstract: Disclosed herein are protein kinase inhibitors, more particularly novel quinazoline derivatives and pharmaceutical compositions thereof, and method of use thereof.
    Type: Application
    Filed: July 17, 2014
    Publication date: June 16, 2016
    Applicant: Shanghai Fochon Pharmaceutical Co Ltd
    Inventors: Weibo Wang, Xingdong Zhao, Tongshuang Li, Qiang Tian, Ling Chen, Zuwen Zhou, Zhifu Li, Xianlong Wang, Yue Rong, Lihua Jiang, Yanxin Liu, Jing Sun
  • Certain protein kinase inhibitors
    Patent number: 9206166
    Abstract: Disclosed herein are protein kinase inhibitors, more particularly novel pyrimidine derivatives and pharmaceutical compositions thereof, and method of use thereof.
    Type: Grant
    Filed: November 5, 2013
    Date of Patent: December 8, 2015
    Assignees: Shanghai Institute of Materia Medica Academy of Sciences, Shanghai Fochon Pharmaceutical Co., LTD
    Inventors: Weibo Wang, Meiyu Geng, Jian Ding, Xingdong Zhao, Jing Ai, Qiang Tian, Xia Peng, Weipeng Zhang, Hongbin Liu, Haohan Tan, Ling Chen
  • CERTAIN PROTEIN KINASE INHIBITORS
    Publication number: 20140128387
    Abstract: Disclosed herein are protein kinase inhibitors, more particularly novel pyrimidine derivatives and pharmaceutical compositions thereof, and method of use thereof.
    Type: Application
    Filed: November 5, 2013
    Publication date: May 8, 2014
    Applicants: SHANGHAI iNSTITUTE OF MATERIA MEDICA ACADEMY OF SCIENCES, SHANGHAI FOCHON PHARMACEUTICAL CO., LTD.
    Inventors: Weibo WANG, Meiyu Geng, Jian Ding, Xingdong Zhao, Jing Ai, Qiang Tian, Xia Peng, Weipeng Zhang, Hongbin Liu, Haohan Tan, Ling Chen