Abstract: The present invention relates to the field of medicinal chemistry, and in particular relates to 4-(five-membered heterocyclic pyrimidine/pyridine substituted) amino-1H-3-pyrazolecarboxamide derivatives, the preparation method thereof, pharmaceutical compositions containing these compounds and the medicinal use thereof, especially as protein kinase inhibitors for anti-tumor use.
Type:
Grant
Filed:
January 7, 2014
Date of Patent:
January 24, 2017
Assignee:
SHANGHAI FOSUN PHARMACEUTICAL DEVELOPMENT CO., LTD.
Inventors:
Tao Lu, Yue Wang, Yadong Chen, Yi Lu, Zhanwei Wang, Qiaomei Jin, Taotao Yang, Guowu Lin, Qinglong Guo, Li Zhao