Patents Assigned to Shanghai Genomics, Inc
  • USE OF PYRIDONE DERIVATIVES IN THE PREVENTION OR TREATMENT OF TISSUE OR ORGAN TOXICITY INDUCED BY CYTOTOXIC AGENTS AND RADIATION
    Publication number: 20140249347
    Abstract: The present invention is directed to a novel use of pyridone derivatives such as pirfenidone for the prevention and treatment of damages to tissues or organs induced by various cytotoxic agents, such as chemotherapeutic agents, biologics, immunosuppressants and radiation. Such prophylactic and/or therapeutic effects of the pyridone derivatives make it possible to increase therapeutic dosages of the cytotoxic agent, thereby enhancing the therapeutic efficacy of the cytotoxic agent and radiation therapy.
    Type: Application
    Filed: May 12, 2014
    Publication date: September 4, 2014
    Applicant: Shanghai Genomics, Inc.
    Inventor: Jun Wu
  • Use of pyridone derivatives in the prevention or treatment of tissue or organ toxicity induced by cytotoxic agents and radiation
    Patent number: 8765726
    Abstract: The present invention is directed to a novel use of pyridone derivatives such as pirfenidone for the prevention and treatment of damages to tissues or organs induced by various cytotoxic agents, such as chemotherapeutic agents, biologics, immunosuppressants and radiation. Such prophylactic and/or therapeutic effects of the pyridone derivatives make it possible to increase therapeutic dosages of the cytotoxic agent, thereby enhancing the therapeutic efficacy of the cytotoxic agent and radiation therapy.
    Type: Grant
    Filed: December 17, 2007
    Date of Patent: July 1, 2014
    Assignee: Shanghai Genomics, Inc.
    Inventor: Jun Wu
  • Kinase inhibitors and their use as pharmaceutical agents
    Patent number: 8309550
    Abstract: Described herein are compounds that are inhibitors of one or more protein kinases. Also described are pharmaceutical compositions and medicaments that include the compounds described herein. Also described herein are methods of using such protein kinase inhibitors, alone and in combination with other compounds, for conditions or diseases mediated or dependent upon protein kinases.
    Type: Grant
    Filed: April 27, 2011
    Date of Patent: November 13, 2012
    Assignee: Shanghai Genomics, Inc.
    Inventors: Ying Luo, Fang Shu, Shudong Wang
  • Derivatives of pryidone and use thereof
    Patent number: 8084465
    Abstract: The present invention provides N-substituted-2(1H) pyridones or the pharmaceutical acceptable salts thereof, and the pharmaceutical preparations containing the compounds. The compounds of the present invention can be used to treat various fibrotic diseases effectively, e.g., hepatic fibrosis.
    Type: Grant
    Filed: September 17, 2010
    Date of Patent: December 27, 2011
    Assignee: Shanghai Genomics, Inc.
    Inventor: Xianghui Yi
  • KINASE INHIBITORS AND THEIR USE AS PHARMACEUTICAL AGENTS
    Publication number: 20110263541
    Abstract: Described herein are compounds that are inhibitors of one or more protein kinases. Also described are pharmaceutical compositions and medicaments that include the compounds described herein. Also described herein are methods of using such protein kinase inhibitors, alone and in combination with other compounds, for conditions or diseases mediated or dependent upon protein kinases.
    Type: Application
    Filed: April 27, 2011
    Publication date: October 27, 2011
    Applicant: SHANGHAI GENOMICS, INC
    Inventors: Ying LUO, Fang SHU, Shudong WANG
  • Derivatives of pyridone and the use of them
    Patent number: 7825133
    Abstract: The present invention provides N-substituted-2(1H) pyridones or the pharmaceutical acceptable salts thereof, and the pharmaceutical preparations containing the compounds. The compounds of the present invention can be used to treat various fibrotic diseases effectively, e.g., hepatic fibrosis.
    Type: Grant
    Filed: November 14, 2003
    Date of Patent: November 2, 2010
    Assignee: Shanghai Genomics, Inc.
    Inventor: Xianghui Yi
  • Tumor tag and the use thereof
    Patent number: 7485621
    Abstract: The invention provides a new tumor tag, RL5 protein, the polynucleotide encoding RL5 protein, and the method of producing RL5 protein by recombinant technology. The invention also discloses the use of RL5 protein and the polynucleotides encoding RL5 protein, e.g., in diagnosing and treating tumor, as well as the pharmaceutical composition containing RL5 protein or the antibody against it.
    Type: Grant
    Filed: September 9, 2002
    Date of Patent: February 3, 2009
    Assignee: Shanghai Genomics, Inc.
    Inventors: Jun Wu, Ying Luo
  • Tumor marker and its use
    Patent number: 7462704
    Abstract: The invention provides a new kind of tumor marker RL9/RL10 protein, the polynucleotide encoding the polypeptide, and the method of producing RL9/RL10 protein by recombinant technology. The invention also discloses the use of RL9/RL10 protein and the polynucleotides encoding RL9/RL10 protein, e.g., in diagnosing and treating tumor, as well as the pharmaceutical composition containing RL9/RL10 protein or the antibody against it.
    Type: Grant
    Filed: February 27, 2003
    Date of Patent: December 9, 2008
    Assignee: Shanghai Genomics, Inc
    Inventors: Jun Wu, Ying Luo
  • Tumor tag and the use thereof
    Publication number: 20070275419
    Abstract: The invention provides a new tumor tag, RL5 protein, the polynucleotide encoding RL5 protein, and the method of producing RL5 protein by recombinant technology. The invention also discloses the use of RL5 protein and the polynucleotides encoding RL5 protein, e.g., in diagnosing and treating tumor, as well as the pharmaceutical composition containing RL5 protein or the antibody against it.
    Type: Application
    Filed: September 9, 2002
    Publication date: November 29, 2007
    Applicant: Shanghai Genomics, Inc.
    Inventors: Jun Wu, Ying Luo