Patents Assigned to SHANGHAI GRIT BIOTECHNOLOGY CO., LTD.
  • MODIFIED TUMOR INFILTRATING LYMPHOCYTE AND USE THEREOF
    Publication number: 20240360410
    Abstract: Provided are a modified tumor infiltrating lymphocyte (TIL) and a use thereof. Also provided is a method for culturing the TIL, comprising reducing the expression and/or decreasing the activity of NF-?B pathway inhibitory molecules of the TIL. Further provided is a method for preventing and/or treating tumors by using the TIL.
    Type: Application
    Filed: August 2, 2022
    Publication date: October 31, 2024
    Applicants: SUZHOU GRIT BIOTECHNOLOGY CO., LTD., ZHUHAI TUOYU BIOTECHNOLOGY CO., LTD., SHANGHAI GRIT BIOTECHNOLOGY CO., LTD., SHENZHEN GRIT BIOTECHNOLOGY CO., LTD.
    Inventors: Yarong LIU, Jingwei SUN, Yao SHENG
  • Method for culturing tumor infiltrating lymphocytes
    Patent number: 12110506
    Abstract: A method for culturing tumor infiltrating lymphocytes (TIL), the method comprising co-culturing the expanded TIL with feeder cells after contacting the TIL with a T cell co-stimulatory molecule and/or a T cell growth factor for a period of time. In addition, further provided is a method for preventing and/or treating tumors by means of using the tumor infiltrating lymphocytes of the present application.
    Type: Grant
    Filed: May 18, 2023
    Date of Patent: October 8, 2024
    Assignees: SUZHOU GRIT BIOTECHNOLOGY CO., LTD., SHANGHAI GRIT BIOTECHNOLOGY CO., LTD., ZHUHAI TUOYU BIOTECHNOLOGY CO., LTD., SHENZHEN GRIT BIOTECHNOLOGY CO., LTD.
    Inventors: Yarong Liu, Peipei Zhao
  • MODIFIED TUMOR-INFILTRATING LYMPHOCYTE AND USE THEREOF
    Publication number: 20240197873
    Abstract: Provided are modified tumor-infiltrating lymphocyte and the use thereof, in particular provided is a method for culturing the tumor-infiltrating lymphocyte (TIL), which comprises increasing the expression and/or enhancing the activity of at least one cytokine of the TIL. Also provided is a method for preventing and/or treating tumors by using the tumor-infiltrating lymphocyte.
    Type: Application
    Filed: April 22, 2022
    Publication date: June 20, 2024
    Applicants: SUZHOU GRIT BIOTECHNOLOGY CO., LTD., ZHUHAI TUOYU BIOTECHNOLOGY CO., LTD., SHANGHAI GRIT BIOTECHNOLOGY CO., LTD., ZHUHAI GRIT BIOTECHNOLOGY CO., LTD.
    Inventors: Yarong LIU, Jingwei SUN, Jiahui JIN