Patents Assigned to SHANGHAI JINGXIN BIOLOGY & PHARMACEUTICAL CO., LTD
  • Salt of cyclohexane derivative
    Patent number: 11584731
    Abstract: The present invention provides a maleate, phosphate, sulfate, hydrochloride of a cyclohexane derivative, N?-[trans-4-[2-[7-(benzo[b]thiophene)-7-piperazinyl]ethyl]cyclohexyl]-N,N-dimethylurea, as shown in Formula I and crystal forms thereof. The crystal forms have low hygroscopicity and good stability and are convenient for long-term storage and transportation; or the crystal forms have a long half-life in vivo, high bioavailability and small individual difference, and thus have obvious clinical application advantages.
    Type: Grant
    Filed: August 13, 2019
    Date of Patent: February 21, 2023
    Assignees: Shanghai Jingxin Biology & Pharmaceutical Co., Ltd, Zhejiang Jingxin Pharmaceutical Co., Ltd.
    Inventors: Yue Huang, Fei Zheng, Xiaoyun Fu, Chunlan Tang, Dan Zhu
  • SALT OF CYCLOHEXANE DERIVATIVE
    Publication number: 20210309631
    Abstract: The present invention provides a maleate, phosphate, sulfate, hydrochloride of a cyclohexane derivative, N?-[trans-4-[2-[7-(benzo[b]thiophene)-7-piperazinyl]ethyl]cyclohexyl]-N,N-dimethylurea, as shown in Formula I and crystal forms thereof. The crystal forms have low hygroscopicity and good stability and are convenient for long-term storage and transportation; or the crystal forms have a long half-life in vivo, high bioavailability and small individual difference, and thus have obvious clinical application advantages.
    Type: Application
    Filed: August 13, 2019
    Publication date: October 7, 2021
    Applicants: SHANGHAI JINGXIN BIOLOGY & PHARMACEUTICAL CO., LTD, ZHEJIANG JINGXIN PHARMACEUTICAL CO., LTD.
    Inventors: Yue HUANG, Fei ZHENG, Xiaoyun FU, Chunlan TANG, Dan ZHU