Abstract: A universal door lock-driving assembly is installed in an exterior space of a door panel. The door panel is furnished with at least one of an embedded lock cartridge, an embedded vertical-extending lock bar assembly and an exposed vertical-extending lock bar assembly. The universal door lock-driving assembly includes a base set, an action unit, a driving member and a slidable unit. The slidable unit can assemble a first assembling member and a second assembling member. The first assembling member can apply a penetration slot on the base set to generate interaction with the embedded lock cartridge or the embedded vertical-extending lock bar assembly. The second assembling member can interact with an exposed lock bar. Thus, the universal door lock-driving assembly can be used to unlock at least the lock cartridge and the lock bar assembly.