Patents Assigned to SHANGHAI RIGHTHAND PHARMTECH, CO., LTD.
  • Agomelatine sulfuric acid complex, and preparation method and application thereof
    Patent number: 9409857
    Abstract: The present invention relates to an Agomelatine sulfuric acid complex in formula (I) and the preparation method thereof (HX=H2SO4, RSO3H (R?CH3, Ph, 4-CH3Ph)). The solubility of the Agomelatine sulfuric acid complex obtained by the method of the present invention is significantly improved compared with Agomelatine, has good stability and higher purity, and is suitable for application in finished-product medicinal preparations. The preparation process is quite simple, and a product with high purity can be obtained without special operations.
    Type: Grant
    Filed: May 14, 2013
    Date of Patent: August 9, 2016
    Assignee: SHANGHAI RIGHTHAND PHARMTECH, CO., LTD.
    Inventors: Haiping Wang, Cheng Chi, Zhengming Chi, Jin Wang, Guanyu Xu