Patents Assigned to Shanghai Ruizhikang Medical Technology Co., Ltd.
  • Publication number: 20240066177
    Abstract: The present disclosure provides a hydrophilic fiber membrane with a sustained-release drug, and belongs to the field of biological materials. The present disclosure provides a hydrophilic fiber membrane with a sustained-release drug, including a fiber with a core-shell structure, where a core of the fiber includes curcumin and a first spinnable polymer, and a shell of the fiber includes polyethylene glycol and a second spinnable polymer; and in the shell, the polyethylene glycol and the second spinnable polymer have a mass ratio of not greater than 1:12. In the present disclosure, the fiber membrane has a core-shell structure, the curcumin is provided in the core, and the shell prevents a rapid release of the curcumin in an early stage, thereby delaying a release rate of the curcumin to prevent the drug from forming a burst release in the early stage and causing toxic reactions.
    Type: Application
    Filed: November 11, 2022
    Publication date: February 29, 2024
    Applicant: SHANGHAI RUIZHIKANG MEDICAL TECHNOLOGY CO., LTD.
    Inventors: Xiaohong CHEN, Yubo LIU, Honglei ZHOU, Wei LI, Fengcang MA, Shaoli FU, Guosen SHAO, Haochen WU
  • Publication number: 20240066182
    Abstract: The present disclosure provides a fiber membrane and a preparation method and use thereof, and belongs to the field of biological materials. The fiber membrane includes a fiber with a core-shell structure, where a core of the fiber includes simvastatin and a first spinnable polymer, and a shell of the fiber includes hydroxyapatite and a second spinnable polymer. In the fiber, a release of the simvastatin mainly depends on a rate of water invasion. After water invades the fiber, the simvastatin in the fiber leaves the fiber with the diffusion of water. In the present disclosure, a barrier function of the shell prevents moisture from entering the core. Therefore, the simvastatin in the core cannot leave the fiber with the diffusion of water molecules in an early stage, and a release rate of drugs is slowed down in the early stage, thereby controlling sustained release of the drugs.
    Type: Application
    Filed: November 10, 2022
    Publication date: February 29, 2024
    Applicant: SHANGHAI RUIZHIKANG MEDICAL TECHNOLOGY CO., LTD.
    Inventors: Xiaohong CHEN, Yubo LIU, Honglei ZHOU, Wei LI, Fengcang MA, Shaoli FU, Guosen SHAO, Haochen WU
  • Patent number: 11661643
    Abstract: The present disclosure discloses use of a copper-chromium alloy in a medical biopsy puncture needle. The copper-chromium alloy used as a material for a needle core and/or needle tube of the puncture needle. The copper-chromium alloy includes the following components by mass: 10?Cr?20, 0.04?Zr?0.1, and the balance of Cu. According to the present disclosure, a copper alloy with designed components is obtained by combining a diamagnetic material Cu with paramagnetic Cr and Zr, and compared with existing medical stainless steel and titanium alloy, the copper alloy has greatly reduced magnetic susceptibility, and specifically, the artifact area and volume are also significantly reduced. In addition, the blank of use of the copper alloy in medical biopsy paracentesis is filled.
    Type: Grant
    Filed: July 7, 2022
    Date of Patent: May 30, 2023
    Assignee: Shanghai Ruizhikang Medical Technology Co., Ltd.
    Inventors: Xiaohong Chen, Honglei Zhou, Shaoli Fu, Fengcang Ma, Guosen Shao, Haochen Wu
  • Publication number: 20230040731
    Abstract: The present disclosure discloses use of a copper-chromium alloy in a medical biopsy puncture needle. The copper-chromium alloy used as a material for a needle core and/or needle tube of the puncture needle. The copper-chromium alloy includes the following components by mass: 10?Cr?20, 0.04?Zr?0.1, and the balance of Cu. According to the present disclosure, a copper alloy with designed components is obtained by combining a diamagnetic material Cu with paramagnetic Cr and Zr, and compared with existing medical stainless steel and titanium alloy, the copper alloy has greatly reduced magnetic susceptibility, and specifically, the artifact area and volume are also significantly reduced. In addition, the blank of use of the copper alloy in medical biopsy paracentesis is filled.
    Type: Application
    Filed: July 7, 2022
    Publication date: February 9, 2023
    Applicant: Shanghai Ruizhikang Medical Technology Co., Ltd.
    Inventors: Xiaohong CHEN, Honglei ZHOU, Shaoli FU, Fengcang MA, Guosen SHAO, Haochen WU